Genotoxic effects of dithane M-45 on the bone marrow cells of mice in vivo

Genotoxic effects of dithane M-45 were studied on the bone marrow cells of male albino mice (Lacca strain) in vivo. Different doses (30 mg, 40 mg and 300 mg/kg b.wt) of dithane M-45 were injected intraperitoneally and their effects were investigated after time intervals of 1, 2, 5 and 10 days. The chromosomal aberrations observed in the bone marrow cells of male mice after treatment with dithane M-45 were fragments, rings, dicentric chromosomes, terminal chromatid deletions, chromatid gaps and breaks. In addition to these chromosomal aberrations, physiological effects such as uneven stretching of chromatin material, end-to-end chromosomal associations, exchange configurations, clumping, stickiness and centromeric associations were also observed.     

Oberflächenspannung und Schallgeschwindigkeit

Summary The preceding empirical relation was found between the surface tension of liquids, the specific weight of liquids, and the velocity of sound:=6.3 · 10^{–4 3/2}. In place of the vèocity of sound can be used, with suitable changes in the equation, the compressibility or, in the case of solid substances, the elasticity of the material in question. The range of validity of this relation is so large that it is possible by means of it to calculate the surface tension of solid substances and of gases.