全文获取类型
收费全文 | 43085篇 |
免费 | 131篇 |
国内免费 | 151篇 |
专业分类
系统科学 | 328篇 |
丛书文集 | 868篇 |
教育与普及 | 79篇 |
理论与方法论 | 142篇 |
现状及发展 | 19129篇 |
研究方法 | 1640篇 |
综合类 | 20428篇 |
自然研究 | 753篇 |
出版年
2013年 | 299篇 |
2012年 | 575篇 |
2011年 | 1326篇 |
2010年 | 240篇 |
2008年 | 680篇 |
2007年 | 819篇 |
2006年 | 776篇 |
2005年 | 810篇 |
2004年 | 860篇 |
2003年 | 763篇 |
2002年 | 738篇 |
2001年 | 1259篇 |
2000年 | 1214篇 |
1999年 | 790篇 |
1992年 | 793篇 |
1991年 | 624篇 |
1990年 | 671篇 |
1989年 | 614篇 |
1988年 | 616篇 |
1987年 | 643篇 |
1986年 | 648篇 |
1985年 | 876篇 |
1984年 | 633篇 |
1983年 | 530篇 |
1982年 | 462篇 |
1981年 | 498篇 |
1980年 | 625篇 |
1979年 | 1373篇 |
1978年 | 1068篇 |
1977年 | 1026篇 |
1976年 | 858篇 |
1975年 | 914篇 |
1974年 | 1256篇 |
1973年 | 1068篇 |
1972年 | 1146篇 |
1971年 | 1304篇 |
1970年 | 1773篇 |
1969年 | 1384篇 |
1968年 | 1197篇 |
1967年 | 1240篇 |
1966年 | 1146篇 |
1965年 | 862篇 |
1964年 | 263篇 |
1959年 | 487篇 |
1958年 | 846篇 |
1957年 | 604篇 |
1956年 | 492篇 |
1955年 | 449篇 |
1954年 | 496篇 |
1948年 | 333篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
281.
282.
283.
Immune response (Ir) genes are linked to the species histocompatibility complex and define as yet uncharacterised phenotypic products which control the immune response to thymus dependent antigens. Antibody formation and antigen induced T lymphocyte proliferation are two examples of immune phenomena which, in vivo and in vitro, operate under Ir gene influence. To clarify their mechanism of action and cellular location, we have examined the contribution of antigen structure (amino acid sequence and conformation to Ir gene control of antigen recognition by T lymphocytes) as well as to the critical role played by the antigen presenting macrophage in expression of that control. We report that immune response gene control of antigen recognition operates at least in part at the level of the macrophage. 相似文献
284.
285.
S. Y. Dike Meera Kamath J. R. Merchant 《Cellular and molecular life sciences : CMLS》1977,33(8):985-985
Summary A one-step synthesis of hexahydrocannabinoid analogs (HHC) is described making use of the condensation of phenolic ketones and aldehydes with citronellal in the presence of pyridine.Grateful thanks are accorded to Drs L. Chopard and S. Selvavinayakam for spectral measurements and Dr I. Fleming for useful discussion.R. Mechoulam and Y. Gaoni, Recent advances in the chemistry of Hashish, in: Progress in the Chemistry of Organic natural products, vol. 25, p. 175. Ed. L. Zechmeister. Springer Verlag, Wien 1967; R. Mechoulam, Marijuana Chemistry and Pharmacology, metabolism and clinical effects. Academic Press, New York 1973; R. Mechoulam, N. K. McCallum and S. Burstein, Chem. Rev.76, 75 (1976). 相似文献
286.
287.
L. Minale C. Pizza R. Riccio F. Zollo 《Cellular and molecular life sciences : CMLS》1983,39(6):569-571
Summary On the basis of comparative spectral data, the structures of 3 novel steroidal glycosides from the Mediterranean starfishHacelia attenuata have been elucidated as3, 4 and5. These are further examples of a novel group of 24-O-glycosidated steroids recently encountered in the same species and in the Pacific speciesProtoreaster nodosus.Part 9. L. Minale, C. Pizza, R. Riccio and F. Zollo, Experientia39 (1983) 567. This contribution is part of the Progetto Finalizzato Chimica fine e secondaria del C.N.R., Roma.Acknowledgments. We thank Prof. K. Nakanishi, Columbia University, New York, for FD-mass spectral analyses, the Centro Interfacoltà di Metodologie Chimico-Fisiche for 270 MHz NMR facilities, and Miss R. Aquino for part of the experimental work. 相似文献
288.
M. B. Castillo M. D. Gonzalez G. Burton C. P. Lantos A. Roldán 《Cellular and molecular life sciences : CMLS》1983,39(6):617-618
Summary A dissociation between inhibition of RNA synthesis and cell lysis was observed when thymocytes of adrenalectomized rats were incubated with high concentrations of pregn-4-ene-11-ol-3, 20-dione and pregna-1,4-diene-11-ol-3,20-dione. In contrast, no dissociation of these effects was found with the typical glucocorticoids cortisol and corticosterone, nor with their 1,4-diene analogs under the same conditions.Acknowledgments. This work was supported by grants from the Consejo Nacional de Investigaciones Científicas y Técnicas de la República Argentina to the Instituto de Biologia y Medicina Experimental and the Programa de Regulación Hormonal y Metabólica as well as by financial help from the Secretaría de Ciencia y Tecnología. 相似文献
289.
The ocean as a supplier of food and energy 总被引:1,自引:0,他引:1
Howard A. Wilcox 《Cellular and molecular life sciences : CMLS》1982,38(1):31-35
Summary This paper presents the concept of raising seaweeds and other valuable organisms with the aid of huge structures (ocean farms) emplaced in the surface waters of the open oceans. Potential advantages from and difficulties to be expected in realizing the associated technologies are briefly set forth. Much of the published literature pertaining to the concept is referenced and summarized. Wave-powered upwelling of cool, nutrient-rich waters through vertical pipes extending to depths of 100–300 m is indicated as desirable. Technologies are outlined for using the harvested seaweeds to create foods and other valuable products such as animal feeds, fertilizers, fibers, plastics, synthetic natural gas (methane), and alcohol and gasoline fuels. Results from site selection studies and economic analyses are given. It appears that dynamically positioned farms orbiting with the surface current patterns typically found on the ocean will be most cost-effective. The general conclusion is stated that open ocean farming will become economically more feasible as the cheaper fossil fuels and food producing lands of the earth become increasingly consumed in the course of the next century. 相似文献
290.
Å. Wiberg R. Adolfsson B. Eckert B. Winblad 《Cellular and molecular life sciences : CMLS》1982,38(1):71-73
Summary The activities of monoamine oxidases A and B towards 5-hydroxytryptamine and -phenethylamine, respectively, were compared in the left and right caudatus, hippocampus, parietal cortex, cerebellum and frontal cortex 6 months after gamma-irradiation (single dose of 23 Gy) of either the right hemisphere or of the whole rabbit brain (in which case, a dose of 16 Gy). No difference in monoamine oxidase A or B activities were found in any of the brain regions.Acknowledgment. This study was supported by grants from the Swedish Medical Research Council (12x–5664 and 04x–4145), Hansson's, Lion's, Mångberg's and Sundblad's funds. 相似文献