直流偏场和面内场共同作用下第Ⅰ类哑铃畴的条泡转变

实验研究了直流偏场和面内场共同作用第Ⅰ类哑铃畴(IDs)的条泡转变现象.实验表明:1)存在3个特征直流偏场,即:条泡转变后的磁畴均为软泡的磁场以及条泡转变后的磁畴中依次出现普通硬磁泡和第Ⅰ类哑铃畴的磁场;2)IDs的最小条泡转变面内场和最大条泡转变面内场均随直流偏场的增加而减小.     

热处理对环境半导体材料β-FeSi2形成的影响

作者对采用非质量分离离子束注入沉积法(IBD)在Si(100)上制备的β-FeSi2薄膜进行了研究,通过X射线衍射(XRD)和扫描电镜(SEM)以及原子力显微镜(AFM)分析表明:当退火温度在600℃和700℃附近时有利于β-FeSi2的形成。     

Loewner矩阵Moore-Penrose逆的快速算法

给出了求以秩为n的m×n阶Loewner矩阵Moore-Penrose逆的快速算法,该算法的计算复杂度为O(mn) O(n2)。     

基于LOGISTIC模型的城市扩展时空模拟——以深圳龙岗区为例

龙岗区是深圳市面积最大的市辖区,在深圳城市扩展中占有重要地位．在综述国内外采用LOGISTIC模型进行土地利用时空模拟的基础上,改进原始模型,将动态交通数据和空间滤波引入模拟流程．以龙岗区为例,基于改进模型尝试对中小尺度的单个城区进行城市扩展的时空模拟．结果显示,模型在中小尺度城市扩展模拟方面具有较好效果．     

条形不耦合平面布药技术在硐室爆破中的应用

为了研究条形药包硐室爆破在复杂环境下的应用问题,首先分析了条形药包的作用机理,根据已有硐室爆破平面药包布设的半理论丰经验公式,建立了条形药包平面布设数学模型。并通过工程实例将条形药包布设理论运用于平面布药实践,缩短了平面布设条形药包的设计周期。研究表明,在山体爆破中采用条形不耦合平面布药技术能显著提高有效松动率,降低大块率,减少二次爆破量。同时也减小了爆破振动对周边环境的破坏影响。     

药物分子对接网格研究与进展

药物分子对接所涉及的搜索空间非常巨大,需要耗费大量的时间,并且对计算环境也有较高的要求．将网格技术应用于药物分子对接中,能有效解决上述问题．通过应用改进的遗传算法多种群竞争机制的对接演化模型GADock,以信息熵控制设计空间的收缩,增强了进化的有效性,显著地提高了对接效率、利用网格数据传输和网格任务调度等网格技术对分子对接过程进行了优化,有效利用了网格节点资源,并降低了药物分子的对接时间．实例测试表明了药物分子对接与网格技术相结合的合理性及有效性．     

刚架拱桥拱索加固体系的受力特性

对某钢筋混凝土刚架拱桥提出了采用拱索体系的加固方法,用空间有限元对其受力特性进行了分析,并与试验测试值进行了比较.研究结果表明,对于用钢缆索斜拉法加固刚架拱桥的新结构,其空间受力效应明显;对处于软土地基上的桥的动力特征分析,必须考虑桥台与地基土壤之问的弹性抗力作用;原拱桥的面外刚度比面内刚度大,反映原拱桥具有足够的横向刚度.     

A mixed-model approach for genome-wide association studies of correlated traits in structured populations

Genome-wide association studies (GWAS) are a standard approach for studying the genetics of natural variation. A major concern in GWAS is the need to account for the complicated dependence structure of the data, both between loci as well as between individuals. Mixed models have emerged as a general and flexible approach for correcting for population structure in GWAS. Here, we extend this linear mixed-model approach to carry out GWAS of correlated phenotypes, deriving a fully parameterized multi-trait mixed model (MTMM) that considers both the within-trait and between-trait variance components simultaneously for multiple traits. We apply this to data from a human cohort for correlated blood lipid traits from the Northern Finland Birth Cohort 1966 and show greatly increased power to detect pleiotropic loci that affect more than one blood lipid trait. We also apply this approach to an Arabidopsis thaliana data set for flowering measurements in two different locations, identifying loci whose effect depends on the environment.     

An efficient multi-locus mixed-model approach for genome-wide association studies in structured populations

Population structure causes genome-wide linkage disequilibrium between unlinked loci, leading to statistical confounding in genome-wide association studies. Mixed models have been shown to handle the confounding effects of a diffuse background of large numbers of loci of small effect well, but they do not always account for loci of larger effect. Here we propose a multi-locus mixed model as a general method for mapping complex traits in structured populations. Simulations suggest that our method outperforms existing methods in terms of power as well as false discovery rate. We apply our method to human and Arabidopsis thaliana data, identifying new associations and evidence for allelic heterogeneity. We also show how a priori knowledge from an A. thaliana linkage mapping study can be integrated into our method using a Bayesian approach. Our implementation is computationally efficient, making the analysis of large data sets (n > 10,000) practicable.     

Research on secure buyer-seller watermarking protocol

A new buyer-seller watermarking protocol is proposed by applying a double encryption method and a novel mechanism of embedding a buyer＇s watermark. The protocol can effectively prevent against collusion attacks and the man in the middle attack if the third party is not trusted. Also, based on the proposed scheme for the first-hand transaction, a new buyer-reseller watermarking protocol and a formal multi-party watermarking protocol are also proposed. The proposed buyer-resell watermarking protocol only needs the original seller to provide transfer certificate and encryption-decryption service to support the second-hand transaction, and the multi-party watermarking protocol with distributed certificate authorities can overcome the difficulty in the combination of multicast mechanism with multiple unique watermarks and allow a seller to multicast the watermarked digital contents and key transaction information to n buyers. Furthermore, the idea of zero knowledge proof is also applied into the proposed scheme to allow the seller to take an effective control on the task performed by the third party.