孟塞尔标号向CIE色座标的转化

本文提出了一种从孟塞尔标号(H、V、C)向CIE色座标(x、y、Y)转化的新方法,该方法利用了牛顿插值公式及二元函数插值法。为了准确迅速地在计算机上实现这种转换,给出了转换程序。     

Bi系超导体工艺研究

本文叙述了Ｂｉ系高温超导体的工艺对其性能的影响，以及对样品进行电击穿实验等。结果表明，高温烧结，液氮淬火，低温退火，缓慢降温有利于生成高温超导体相；超导样品是由一些颗粒连接而成，其击穿电压和零电阻温度成反比。     

人类永恒的主题——中西方爱情小说掠影

爱情是人类作品永恒的主题,并非西方所特有;中西爱情小说同样存在高雅与粗俗两类,我们不能是中非西或是西非中,更不应把“改革开放”与“引进黄祸”挂起钩来。     

一类新的准谐振变换器

用一种新的恒频周期谐振开关代替脉宽调制开关变换器中的开关单元可得到一类新的准谐振变换器：恒频工作的周期准谐振变换器。该类变换器工作过程简单，分析设计容易，负载特性良好，并且克服了传统ＱＲＣ可控范围极有限的缺点。与调频工作周期准谐振变换器相比，新的ＣＦ－ＣＱＲＣ因恒频工作而具有更好的控制性能，使优化设计成为可能。     

铝在冰晶石-氧化铝熔液中溶解机理的量子化学研究

利用EHMO(扩充许克尔分子轨道)函数计算离子数达50个的原子(离子)模型,采用Hoffmann的ICON程序以非迭代方式计算。设计了一系列简单原子簇模型以计算其分子轨道波函数和其他数据,从而考查铝原子和Al~+在不同离子环境中的微观行为。认为Al在Na_3AlF_6-Al_2O_3熔液中溶解反应主要是铝与Al~(3+)和Na~+离子以某种程度的共价键结合,形成[Al_nNa_m]~(x+)一类的原子簇离子。m,n及x的数值有待进一步确定。     

水—醇混合溶剂中[Co(N_3)(NH_3)_5]~(2+)与[Fe(H_2O)_6]~(2+)间电子转移反应机理

本文研究了水—醇(如甲醇、乙醇和正丙醇等)混合溶剂中[Co(N_3)(NH_3)_5]~(2+)与 Fe(Ⅱ)间电子转移反应。其表观速度常数 k_(app)随甲醇、乙醇和正丙醇的摩尔分数X 醇增大(即随混合溶剂介电常数的减小)和酸浓度的增大而增大。反应速度与酸浓度的依存关系,可用[Co(N_3)(NH_3)_5]~(2+)的配体 N_3~-的质子化作用和由此而产生的特殊酸催化作用阐明.[Co(N_3)(NH_3)_5]~(2+)还原反应的表观速度常数 k_(app)可表示为:k_(app)=k_HK_H[H_3O~+]由特殊酸催化而使[Co(N_3)(NH_3)_5]~(2+)被还原反应加速,可认为电子转移是反应的速控步骤。     

隔水管非线性振动的线性化分析

本文在规则波浪与海流联合作用下对海洋钻井隔水管进行了动力分析,对非线性拖曳力采用改进的线性化方法,推导了有限元线性振动方程。求解这些方程几乎象静力方程一样,只需要少数几次迭代就可求得响应最大值。同时给出一些规则波浪与海流联合作用下的算例,并对由本文方法和由非线性时间域动力分析方法分别求得的两种结果进行了比较。比较表明,两种计算结果吻合。本文的线性化方法及把动力方程变换为静力方程的方法,能节约计算机时。隔水管是海洋工程中较典型的构件,该分析方法便于实际应用。     

双曲Riemann曲面上有界调和函数的共轭空间

本文证明了l是HX(R)上的有界线性泛函的充分必要条件是存在h∈L~1(v)使另外还有|l|=|h|_1.其中HX=HB、HBD; v对应地表示R的关于Wiener和Royden边界的调和测度。     

A new immunomodulating compound (AS-101) with potential therapeutic application

There has been interest in the potential of synthetic compounds to modify immune responses by imitation of cytokine action. Direct administration of interleukin 2 (IL-2) in conjunction with adoptive transfer of lymphokine activated killer cells has been used in the treatment of cancer, but there are toxic effects resulting from the high doses of IL-2 required. We have developed a new synthetic compound, ammonium tri-chloro(dioxoethylene-O,O'-)tellurate (AS-101), which has immunomodulating properties and minimal toxicity. The effects of AS-101 on the activation and function of immunocompetent cells have been assessed. We have found that AS-101 induces proliferation and IL-2 production by human lymphocytes in vitro, and enhances the production of IL-2 and colony-stimulating factor by mouse spleen cells. Splenocytes of BALB/c mice injected with AS-101 increased production of IL-2 and CSF in vitro in the presence of mitogen. Mononuclear cells of normal donors acquired responsiveness to recombinant IL-2 and bound monoclonal antibody to IL-2 receptor after incubation with AS-101. Splenocytes of mice treated in vivo with AS-101 expressed high levels of IL-2 receptor. The stimulation of lymphocytes by AS-101 apparently involves an increase in intracellular free calcium. AS-101 administered systemically to mice mediated antitumour effects which could be attributable to its immunomodulatory properties. In addition, AS-101 could directly enhance the ratio of OKT4 to OKT8-positive cells in cultured mononuclear cells from AIDS (acquired immune deficiency syndrome) patients. These results indicate that AS-101 is potentially useful in the treatment of clinical conditions involving immunosuppression.     

HIV-1 superinfection despite broad CD8+ T-cell responses containing replication of the primary virus

Early treatment of acute HIV-1 infection followed by treatment interruptions has shown promise for enhancing immune control of infection. A subsequent loss of control, however, allows the correlates of protective immunity to be assessed. Here we show that sudden breakthrough of plasma viraemia occurred after prolonged immune containment in an individual infected with HIV-1 at a time when 25 distinct CD8+ T-cell epitopes in the viral proteins Gag, RT, Integrase, Env, Nef, Vpr, Vif and Rev were being targeted. Sequencing of the virus in plasma and cells showed that superinfection with a second clade-B virus was coincident with the loss of immune control. This sudden increase in viraemia was associated with a decline in half of the CD8+ T-cell responses. The declining CD8+ T-cell responses were coupled with sequence changes relative to the initial virus that resulted in impaired recognition. Our data show that HIV-1 superinfection can occur in the setting of a strong and broadly directed virus-specific CD8+ T-cell response. The lack of cross-protective immunity for closely related HIV-1 strains, despite persistent recognition of multiple CD8 epitopes, has important implications for public health and vaccine development.