扁平疣种植术、左旋咪唑、潘生丁治疗扁平疣疗效观察

目的：观察扁平疣种植术、口服左旋咪唑、潘生丁治疗扁平疣的短期疗效。方法：85例扁平疣患分为治疗组、对照组，二组患均口服左旋咪唑、潘生丁片；治疗组同时取癌体种植于上臂三角肌。结果：治疗组4d开始出现疗效，总有效率86％，对照组13d开始出现疗效，总有效率48．5％，两组疗效有显差异(P＜0．01)。结论：左旋咪唑、潘生丁具有抗病毒，提高或恢复机体细胞免疫功能，调节抗体产生，同时采用扁平疣种植术，应用自体免疫疗法，通过植入疣体的抗原刺激机体产生抗体，使疣组织在短期内吸收、消失而达到短期治愈的目的。     

循环载荷下缺口板弹塑性应变分布测定

用电测法测定了带有中心圆孔矩形铝合金（ＬＹ－１２－ＣＺ）板在循环载荷作用下横截面的弹塑性应变分布，同时测定了循环载荷下孔边应力──应变回线，弹塑性应变集中系数Ｋε和应力集中系数Ｋσ，并和四种近似公式的计算结果进行了比较。发现在循环加载情况下用电测法绘制载荷──应变回线，并根据回线出现畸变的现象，可以灵敏的检测裂纹的萌生和早期扩展。     

纯位相编码识别方法

本文提出一种纯位相编码识别方法。在光学相关器中使用一种特殊的纯位相编码滤波器,将二值化后的输出响应序列作为目标的识别代码,可以增加光学相关系统的识别能力.     

活性污泥宏基因组Fosmid文库的构建

大插入片段宏基因组文库的构建是开发大片段目的基因及分析其结构与功能的基础.文中分别采用十六烷基三甲基溴化铵(CTAB)法、试剂盒及琼脂糖包埋法提取活性污泥宏基因组DNA,其中琼脂糖包埋法获得的DNA片段大于23kbp,利用此DNA成功构建了以pCC1FOS为载体的Fosmid文库,该文库含有5280个克隆,平均插入片段长度为35～40 kbp,共包含约200 Mbp的宏基因组DNA.从此文库中随机挑选200个克隆,利用活性筛选方法快速筛选到了1个含有淀粉酶的阳性克隆,表明活性污泥Fosmid文库可用于功能基因的活性筛选,具有开发新基因的潜力.     

知识经济时代与信息技术

本文论述了知识经济的由来及主要特征及知识经济时代信息技术的重要性。     

Effect of monoclonal antibody to bull sperm sp18 on murine fertilization and embryos development

Western blot analysis revealed that one IgG1 monoclonal antibody (mAb) to sp18 family membrane proteins (Mr. 14, 16 and 18 ku) of bovine sperm reacted faintly with protein bands of 14, 18, 22, 30 and 60 ku (reducing) in samples of mouse sperm. The mAb also reacted to protein of egg lysozyme. Using a laser confocal microscope, indirect immunofluorescence (IIP) showed that the sp18 antigens were present in the posterior head of murine sperm. In murine in vitro fertilization (IVF) and embryo development trails, a total of 426 oocytes from C57BL/6 and F1 hybrid strain (CD1 × C57BL/6 cross) of 12 female mice were used in 3 independent trails. After preincubating capacitated sperm with 182 μg/mL of sp18 mAb in the modified TYH IVF medium for 15-20 min, cumulus-oocyte-complexes were introduced. The fertilization rate in sp18 mAb groups was 77.1 %, which was not significantly (P > 0.05) different from the nonspecific mouse IgG (79.2%) and non-IgG (80.3 %) control groups. Fertilized oocytes had been continuously cultured in modifed CZB medium. 100%, 100% and 97.9% of 1-cell embryos developed to 2-cell stage in sp18 mAb, nonspecific mouse IgG and non-IgG group 30 h after the start of fertilization, respectively. In the nonspecific mouse IgG and non-IgG groups, 64.1 % and 64.3% of embryos developed to the 4-cell stage, respectively, but all developing eggs in sp18 mAb groups arrested development in vitro at 2-cell stage. After zonae of 2-cell blocked embryos were enzy-matically removed with 0.5% pronase, detection of sp18 antigens by IIF indicated that the fluorescence scattered on two embryonic cells. For embryos fertilized in vivo and co-cultured with 182 μg/mL sp18 mAb, the numbers of 1-cell embryos reaching the 2-cell and 4-cell stage were 95. 2% and 70. 5%, which were not significantly (P>0.05) different from the control group (92.9% and 77.9%). These results indicate that the sp18 antigens on posterior head of mouse sperm were incorporated into the egg plasma membrane during fertilization, and played an active role in development of murine preimplanta-tion embryo.     

库车前陆盆地构造特征及缩短量研究--以BC95-230剖面为例

库车坳陷是一种新型的前陆盆地,其构造样式以类型Ⅱ三角带为特征。复杂构造区的层面在二维平面内可看作为一条曲线,从而可运用分形几何学方法由分数维来定量描述。运用平衡剖面技术和分形方法,以ＢＣ９５－２３０ 剖面为例,进行了缩短量和剖面应变计算。分析结果表明,Ｎ１ 底界曲面的分维值为１．０４９１,缩短量达３５．２６７ ｋｍ ,表现出５０．０５％ 的应变。由于受层间滑动等多种地质因素的影响,平衡剖面技术计算结果存在较大误差。因此,要正确平衡地质剖面,必须对小尺度范围的应变进行分析     

基于地理信息系统与斜坡单元的峨边县地质灾害易发性评价

斜坡单元依据山脊线和山谷线划分的单元,能够体现研究区的真实地质环境条件,作为评价单元在地质灾害易发性评价中具有重要意义。采用地理信息系统(geographic information system, GIS),运用水文分析工具提取峨边县斜坡单元,选取归一化植被指数、坡度、高程、地形起伏度、地层岩性、距水系的距离、距断层距离、距道路的距离8个因子,使用逻辑回归模型(logistic regression, LR),制得地质灾害易发性概率图,将其划分为非易发区、低易发区、中易发区、高易发区和极高易发区。结果表明：ROC(receiver operating characteristic curve)曲线的线下面积(area under curve, AUC)精度检验值为0.917,极高易发区和高易发区内地质灾害点数占总灾害点数的81.3%,说明对峨边县进行基于斜坡单元使用逻辑回归进行地质灾害的易发性评价具有可行性和较高精度。     

A 457-year reconstruction of precipitation in the southeastern Qinghai-Tibet Plateau, China using tree-ring records

This paper presents a 457-year reconstruction of precipitation in the southeastern Qinghai-Tibet Plateau using tree-ring records.Tree-ring samples were collected from the Hengduan Mountains in the southeastern part of the Qinghai-Tibet Plateau,China.A nearly 500-year chronology was developed using tree-ring width records.Correlation analysis shows moisture is the main factor limiting tree growth in this region.Ring-widths were significantly positively correlated with the Palmer Drought Severity Index(PDSI) and precipitation in many months.The highest correlation coefficient was found between the annual growth of trees and precipitation from the previous September to the current June(0.738).Based on this relationship,we reconstructed the precipitation history from 1509 to 2006.The reconstruction explains 54.4%(Radj2=53.5%,N=49,F=56.12) of the actual precipitation variation during the calibration period(1958-2006).During the reliable period of the reconstruction(1549-2006),some low-frequency climate signals are included,indicating this region has been getting wetter in the last 20 years.The reconstruction documents six apparently dry and five pluvial periods and the 17th century dry period lasted longer than any other.When compared with other recent studies,this study and these earlier reconstructions show a similar trend in the variation of drought and pluvial.Further spatial correlation analysis confirms that the reconstructed precipitation adequately represents the rainfall history of the entire Hengduan Mountain area.The Multi-taper method,a type of spectral analysis,reveals that precipitation in this area had significant(P<0.01) spectral peaks at 3-5 a,60 a and 79-85 a.     

在物化之后寻找人——卢卡奇《历史与阶级意识》解读

青年卢卡奇创造性地提出了物化的概念,这与马克思的异化劳动十分相像。不过,卢卡奇的物化主要是对资本主义的负面批评,而马克思的异化劳动则看到了辩证性的一面。卢卡奇认为克服物化的方法是总体性,而总体性的执行者是无产阶级,但这种思想却有使无产阶级物化的危险。今天,克服物化仍是这个社会的主要问题,我们还是应该回到马克思关于实践的前提下,以更加丰富和多元的姿态来理解总体性,从而寻找人本身。