阿魏菇对荷瘤小鼠机体免疫功能的影响研究

从免疫学角度探讨了阿魏菇(Pleurotus Ferulae)抑制肿瘤的作用机理.实验中采用在小鼠体内建立S180移植肿瘤模型的方法,其中两组注射环磷酰胺造成免疫抑制模型.用1 g/kg的阿魏菇对小鼠连续灌胃10天后测定其抑瘤率,同时观察阿魏菇对小鼠免疫器官的影响;鸡红细胞半体内法观察阿魏菇对小鼠腹腔巨噬细胞吞噬功能的影响;MTT法测定阿魏菇对外周血NK细胞影响;溶血素法测定阿魏菇对小鼠血清中抗体水平的影响.研究结果表明阿魏菇对S180肉瘤有明显的抑制作用,抑瘤率可达64.97%,同时,阿魏菇可明显促进荷瘤小鼠腹腔巨噬细胞的吞噬功能、外周血NK细胞的免疫活性,提高体液免疫功能,增加脾指数,并且可显著增强环磷酰胺模型小鼠的免疫功能.即阿魏菇可通过促进小鼠机体免疫功能抑制S180肿瘤的增殖.     

距离矢量路由算法的改进方案

距离矢量路由算法是一种典型的动态路由选择算法,此算法容易理解和实现,在实际网络中应用广泛。文章分析了该算法存在的路由环和无穷计算等缺陷,并给出了相应的解决方案.     

分散介质及分散剂对丙烯酰胺分散聚合的影响研究

以醇/水混合溶剂为分散介质,聚乙烯吡咯烷酮（PVP）为分散稳定剂,采用分散聚合法制备聚丙烯酰胺（PAM）。讨论了醇的种类、醇水比及PVP的用量对丙烯酰胺（AM）分散聚合的影响。结果表明：醇水比（体积比）为50：50时,制备的PAM较稳定,单体转化率高;PVP添加量为单体含量的15％时,能制得较高分子量的PAM。     

纹理表达在图像压缩中的应用

本文针对静止纹理图像展开研究,详细阐述了基于高斯马尔科夫随机场参数和基于样图这两种纹理分析合成技术的原理及其实现,综合二维自相关纹理统计分析方法形成了一套针对不同类型的纹理图像自适应地选择表达合成方法的方案.实验表明,所提方案能够压缩图像数据量,是对新一代图像编码的一种探索.     

广义长方形Sierpinski地毯的Hausdorff测度

利用Sierpinski地毯的自相似结构。得到Hausdorff测度的上界,通过在Sierpinski地毯上定义一个质量分布,利用质量分布原理得到测度的下界,从而得到了所定义的长方形Sierpinski地毯的Hausdorff测度的准确值。     

The complete genome of an individual by massively parallel DNA sequencing

The association of genetic variation with disease and drug response, and improvements in nucleic acid technologies, have given great optimism for the impact of 'genomic medicine'. However, the formidable size of the diploid human genome, approximately 6 gigabases, has prevented the routine application of sequencing methods to deciphering complete individual human genomes. To realize the full potential of genomics for human health, this limitation must be overcome. Here we report the DNA sequence of a diploid genome of a single individual, James D. Watson, sequenced to 7.4-fold redundancy in two months using massively parallel sequencing in picolitre-size reaction vessels. This sequence was completed in two months at approximately one-hundredth of the cost of traditional capillary electrophoresis methods. Comparison of the sequence to the reference genome led to the identification of 3.3 million single nucleotide polymorphisms, of which 10,654 cause amino-acid substitution within the coding sequence. In addition, we accurately identified small-scale (2-40,000 base pair (bp)) insertion and deletion polymorphism as well as copy number variation resulting in the large-scale gain and loss of chromosomal segments ranging from 26,000 to 1.5 million base pairs. Overall, these results agree well with recent results of sequencing of a single individual by traditional methods. However, in addition to being faster and significantly less expensive, this sequencing technology avoids the arbitrary loss of genomic sequences inherent in random shotgun sequencing by bacterial cloning because it amplifies DNA in a cell-free system. As a result, we further demonstrate the acquisition of novel human sequence, including novel genes not previously identified by traditional genomic sequencing. This is the first genome sequenced by next-generation technologies. Therefore it is a pilot for the future challenges of 'personalized genome sequencing'.     

Item-level Forecasting for E-commerce Demand with High-dimensional Data Using a Two-stage Feature Selection Algorithm

With the rapid development of information technology and fast growth of Internet users,e-commerce nowadays is facing complex business environment and accumulati...     

Small-Space Microphone Array Fractional Delay Algorithm Based on FIR Filter for Cochlear Implant

Directional speech enhancement of signals from microphone arrays is an effective way to improve speech recognition for cochlear implant users.The strict implant size limitation results in a short distance between microphones.The fractional delay problem due to the short distance between microphones is solved by a maximal flat (Maxflat) finite impulse response (FIR) filter,using the Maxflat error criteria at a low frequency containing most of the speech information and energy.The fractional Maxflat FIR filter approximates the ideal digital fractional filter at the magnitude response,phase response,and phase delay characteristics,and is also very low order.The results demonstrate that the Maxflat FIR filter accurately and effectively solves the fractional digital delay and is very suitable for real-time speech processing in practical cochlear implant products.     

论师范生教师专业技能一体化的层级训练框架的建构

基础教育课程改革的深化、高等院校师范生"整合连贯型"教师教育培养模式的逐步构建,对师范生的教师专业技能提出了更高的要求.在建构师范生教师专业技能一体化的层级训练框架中,其框架呈现状态为:课堂观察→教学设计的文案形式→教学设计的讲台运作形式→教学测评手段.探寻师范生教师技能训练的可行性有效性的操作方法,培养既能承担小学教育,又能承担中学教育的高素质新型基础教育师资.     

GF(3)上一类几乎平衡的6阶分圆序列

具有良好自相关性的伪随机序列在信息安全等领域中有着广泛的应用.在GF(3)上构造一类周期为p的几乎平衡6阶分圆序列,利用6阶分圆数计算出该序列的自相关值,并进一步给出满足适当条件的素数p,使得这类序列的自相关值为3值.