三溴苯酚系列阻燃剂的合成及其在环氧树脂中的阻燃效果

报道了三溴苯酚系列中三种阻燃剂:2、4、6-三溴苯酚缩水甘油醚、2、4、6-三溴苯酚亚磷酸酯和2、4、6-三溴苯酚磷酸酯的合成方法及其对E-44型环氧树脂的阻燃效果,研究结果表明:上述三种阻燃剂采用本文介绍的合成方法所得产品的产率和纯度都很高,对环氧树脂表现出良好的阻燃效果。同时,还得出在分子结构中同时含有溴、磷两种阻燃元素的2、4、6-三溴苯酚磷酸酯比相应的溴化物和磷化物的混合物阻燃协同效应要好的结论。     

液晶化合物的质谱研究：Ⅰ.手性苯基吡啶,苯基嘧啶类液晶

对手性苯基吡啶、苯基嘧啶类液晶共十九个化合物进行了电子轰击质谱和化学电离质谱测定，讨论了它们的质谱特征和裂解机理。     

圈流磨负荷微机控制系统

本文对圈流磨负荷采用了三环串级调节的控制方式,有效地解决了在磨机生产中因物料易磨性的变化引起工况不稳定的问题,使磨机能始终稳定地运行在高效状态。     

关节水平的“共驱动”研究

本文以主动肌和拮抗肌的协同作用机理为依据,从表面肌电(EMG)信号的频率参数和肌肉平均传导速度两个方面,对近年来提出的正常人体神经肌肉系统控制的新理论——“共驱动”概念,在关节水平上进行了探讨和研究,实验结果表明:膝关节的主动肌和拮抗肌在持续恒力收缩下,其表面EMG信号功率谱的归一化中值频率随着时间的增加而同时下降;两路EMG信号的归一化中值频率之间的互相关系数随着收缩力的减小而减小,肘关节的肱二头肌不论是作为主动肌还是拮抗肌,在持续恒力收缩下,由表面EMG信号估计得到的肌肉的平均传导速度均随着收缩时间的增加而下降;肱二头肌作为拮抗肌时,平均传导速度明显高于其作为主动肌时的平均传导速度。     

Subtractive proteomic mapping of the endothelial surface in lung and solid tumours for tissue-specific therapy

The molecular complexity of tissues and the inaccessibility of most cells within a tissue limit the discovery of key targets for tissue-specific delivery of therapeutic and imaging agents in vivo. Here, we describe a hypothesis-driven, systems biology approach to identifying a small subset of proteins induced at the tissue-blood interface that are inherently accessible to antibodies injected intravenously. We use subcellular fractionation, subtractive proteomics and bioinformatics to identify endothelial cell surface proteins exhibiting restricted tissue distribution and apparent tissue modulation. Expression profiling and gamma-scintigraphic imaging with antibodies establishes two of these proteins, aminopeptidase-P and annexin A1, as selective in vivo targets for antibodies in lungs and solid tumours, respectively. Radio-immunotherapy to annexin A1 destroys tumours and increases animal survival. This analytical strategy can map tissue- and disease-specific expression of endothelial cell surface proteins to uncover novel accessible targets useful for imaging and therapy.     

Mutations in SEC63 cause autosomal dominant polycystic liver disease

Mutations in PRKCSH, encoding the beta-subunit of glucosidase II, an N-linked glycan-processing enzyme in the endoplasmic reticulum (ER), cause autosomal dominant polycystic liver disease. We found that mutations in SEC63, encoding a component of the protein translocation machinery in the ER, also cause this disease. These findings are suggestive of a role for cotranslational protein-processing pathways in maintaining epithelial luminal structure and implicate noncilial ER proteins in human polycystic disease.     

Decision cost feature weighting and its application in intrusion detection

This paper introduces the cost sensitive feature weighting strategy and its application in intrusion detection. Cost factors and cost matrix are proposed to demonstrate the misclassification cost for IDS. How to get the whole minimal risk. is mainly discussed in this paper in detail. From experiments, it shows that although decision cost based weight learning exists somewhat attack miselassifieation, it can achieve relatively low misclassification costs on the basis of keeping relatively high rate of recognition precision.     

Assessment of rice fields by GIS／GPS-supported classification of MODIS data

The new Moderate-Resolution Imaging Spectroradiometer (MODIS) satellite image offers a large choice of opportunities for operational applications. The 1-km Advanced Very High Resolution Radiometer (AVHRR) image is not suitable for retrieval of field level parameter and Landsat data are not frequent enough for monitoring changes in crop parameters during the critical crop growth periods.A methodology to map areas of paddy fields using MODIS,geographic information system (GIS) and global position system (GPS) is introduced in this paper. Training samples are selected and located with the help of GPS to provide maximal accuracy.A concept of assessing areas of potential cultivation of rice is suggested by means of GIS integration. By integration of MODIS with GIS and GPS technologies the actual areas of rice fields in 2002 have been mapped. The classification accuracy was 95.7% percent compared with the statistical data of the Agricultural Bureau of Zhejiang Province.     

Production of bacterial blight resistant lines from somatic hybridization between Oryza sativa L. and Oryza meyeriana L

Novel bacterial blight (BB) resistance gene(s) for rice was (were) introduced into a cultivated japonica rice variety Oryza sativa (cv. 8411), via somatic hybridization using the wild rice Oryza meyeriana as the donor of the resistance gene(s). Twenty-nine progenies of somatically hybridized plants were obtained. Seven somatically hybridized plants and their parents were used for AFLP (amplified fragment length polymorphism) analysis using 8 primer pairs. Results confirmed that these plants were somatic hybrids containing the characteristic bands of both parents. The morphology of the regenerated rice showed characters of both O.sativa and O.meyeriana. Two somatic hybrids showed highest BB resistance and the other 8 plants showed moderate resistance. The new germplasms with highest resistance have been used in the rice breeding program for the improvement of bacterial blight resistance.