现代商业室内环境中柱的利用与柱式设计

对现代商业室内环境艺术中柱的合理利用及柱的造型设计进行了探讨,并利用大量中外设计实例具体阐述了现代商业室内环境设计中柱的处理及柱式设计的原则与方法。     

全彩色LED显示屏真彩色显示技术研究

该文研究了在全彩色ＬＥＤ显示系统中应用基色转换技术实现图像的真彩色显示。由于彩色ＬＥＤ显示屏所选用的三基色与电视系统三基色在光谱特性上有着较大差别,同一颜色在２个不同的色度系统中,其三刺激值必然不同。为了真实地再现视频图像信息,ＲＧＢ信号在送给彩色ＬＥＤ显示屏之前必须进行基色变换处理。文中叙述了基色转换的方法,并针对实际系统给出其彩色校正矩阵及其硬件实现。实验结果表明,通过校正处理能有效地减小颜色再现色差,提高图像的视觉质量。     

系统参数重要性评价方法

系统参数的重要性评价十分重要,本文首先讨论了通过计算特征参数的离差来分析系统参数重要性的Ｋ-Ｗ检验方法,研究了利用信息论中不确定性概念来计算熵与分类的关系的方法,以及通过计算系统参数的之间的依赖性和不可分辨性与识别系统的关系来衡量系统参数重要性的粗集理论分析方法,最后,我们给出分析属性重要性的例子,分析和比较他们之间的关系。     

SQL注入攻击原理及其防范技术研究

对SQL注入攻击的特点、实现原理、检测方法以及防范方法进行了阐述和总结,并且建立了SQL注入攻击自动防范模型.经过测试证明,该模型具有计算时间复杂度低、安全性和通用性等特点,能够很好地进行主动防范,具备较高的实用价值.     

基于CPN的智能合约交易顺序依赖漏洞的验证

智能合约的形式化验证工作主要集中在编程语言层面的漏洞研究,而交易顺序依赖作为区块链层面的漏洞更不易被检测。基于着色Petri网对智能合约中潜在的交易顺序依赖漏洞进行形式化验证。以Decode悬赏合约为对象,分析合约中潜在的漏洞,自顶向下地对合约本身及其执行环境建立着色Petri网模型,并引入攻击者模型来考虑合约遭受攻击的情况。通过运行模型以验证合约存在交易顺序依赖漏洞,最后基于Remix平台在以太坊网络中证实结论的正确性。     

锥阀稳态液动力及阀芯表面压力分布数值模拟

基于Fluent流场仿真软件,对锥阀外流和内流情况下阀芯所受稳态液动力及阀芯表面压力分布进行了数值模拟和分析。结果表明,稳态液动力随着阀口压差的增大而增加;当阀口压差大于2.5MPa时,阀芯表面出现负压,阀口处发生气蚀;当阀口开度为1mm时,稳态液动力最大;在其他条件相同的情况下,锥阀内流时的液动力小于锥阀外流时的液动力。     

Genome-wide association studies of 14 agronomic traits in rice landraces

Uncovering the genetic basis of agronomic traits in crop landraces that have adapted to various agro-climatic conditions is important to world food security. Here we have identified ～ 3.6 million SNPs by sequencing 517 rice landraces and constructed a high-density haplotype map of the rice genome using a novel data-imputation method. We performed genome-wide association studies (GWAS) for 14 agronomic traits in the population of Oryza sativa indica subspecies. The loci identified through GWAS explained ～ 36% of the phenotypic variance, on average. The peak signals at six loci were tied closely to previously identified genes. This study provides a fundamental resource for rice genetics research and breeding, and demonstrates that an approach integrating second-generation genome sequencing and GWAS can be used as a powerful complementary strategy to classical biparental cross-mapping for dissecting complex traits in rice.     

Exome sequencing of liver fluke-associated cholangiocarcinoma

Opisthorchis viverrini-related cholangiocarcinoma (CCA), a fatal bile duct cancer, is a major public health concern in areas endemic for this parasite. We report here whole-exome sequencing of eight O. viverrini-related tumors and matched normal tissue. We identified and validated 206 somatic mutations in 187 genes using Sanger sequencing and selected 15 genes for mutation prevalence screening in an additional 46 individuals with CCA (cases). In addition to the known cancer-related genes TP53 (mutated in 44.4% of cases), KRAS (16.7%) and SMAD4 (16.7%), we identified somatic mutations in 10 newly implicated genes in 14.8-3.7% of cases. These included inactivating mutations in MLL3 (in 14.8% of cases), ROBO2 (9.3%), RNF43 (9.3%) and PEG3 (5.6%), and activating mutations in the GNAS oncogene (9.3%). These genes have functions that can be broadly grouped into three biological classes: (i) deactivation of histone modifiers, (ii) activation of G protein signaling and (iii) loss of genome stability. This study provides insight into the mutational landscape contributing to O. viverrini-related CCA.     

Genome-wide association study of flowering time and grain yield traits in a worldwide collection of rice germplasm

A high-density haplotype map recently enabled a genome-wide association study (GWAS) in a population of indica subspecies of Chinese rice landraces. Here we extend this methodology to a larger and more diverse sample of 950 worldwide rice varieties, including the Oryza sativa indica and Oryza sativa japonica subspecies, to perform an additional GWAS. We identified a total of 32 new loci associated with flowering time and with ten grain-related traits, indicating that the larger sample increased the power to detect trait-associated variants using GWAS. To characterize various alleles and complex genetic variation, we developed an analytical framework for haplotype-based de novo assembly of the low-coverage sequencing data in rice. We identified candidate genes for 18 associated loci through detailed annotation. This study shows that the integrated approach of sequence-based GWAS and functional genome annotation has the potential to match complex traits to their causal polymorphisms in rice.     

考虑专家信息的威布尔型产品定时截尾可靠性验收试验方案设计

可靠性验收试验是检验产品是否达到可靠性要求而进行的试验。试验方案的确定需要保证使用方风险和生产方风险可控。当前GJB899A中定时截尾试验方案往往需要较长的试验时间,短时试验方案又存在两类风险较大的问题,实际应用颇受诟病。根本原因在于GJB899A的试验方案确定只考虑了系统试验数据,而忽视了其多源信息。因此,本文针对复杂系统验收试验前存在多种形式专家信息,考虑系统寿命服从威布尔分布的情况,结合专家信息来计算产品在给定试验方案下的两类风险,进一步推导得到试验时间较短、风险可控的试验方案。文章最后给出了案例分析,通过对比,验证了所提方法的有效性。