全文获取类型
收费全文 | 3578篇 |
免费 | 18篇 |
国内免费 | 14篇 |
专业分类
系统科学 | 82篇 |
丛书文集 | 24篇 |
教育与普及 | 7篇 |
理论与方法论 | 10篇 |
现状及发展 | 1634篇 |
研究方法 | 212篇 |
综合类 | 1584篇 |
自然研究 | 57篇 |
出版年
2012年 | 67篇 |
2011年 | 120篇 |
2010年 | 30篇 |
2009年 | 29篇 |
2008年 | 91篇 |
2007年 | 84篇 |
2006年 | 92篇 |
2005年 | 84篇 |
2004年 | 114篇 |
2003年 | 74篇 |
2002年 | 80篇 |
2001年 | 109篇 |
2000年 | 114篇 |
1999年 | 71篇 |
1992年 | 83篇 |
1991年 | 47篇 |
1990年 | 43篇 |
1989年 | 37篇 |
1988年 | 26篇 |
1987年 | 40篇 |
1986年 | 46篇 |
1985年 | 51篇 |
1984年 | 58篇 |
1983年 | 31篇 |
1982年 | 34篇 |
1981年 | 26篇 |
1980年 | 48篇 |
1979年 | 98篇 |
1978年 | 63篇 |
1977年 | 80篇 |
1976年 | 53篇 |
1975年 | 53篇 |
1974年 | 103篇 |
1973年 | 86篇 |
1972年 | 75篇 |
1971年 | 83篇 |
1970年 | 118篇 |
1969年 | 104篇 |
1968年 | 113篇 |
1967年 | 97篇 |
1966年 | 106篇 |
1965年 | 74篇 |
1964年 | 31篇 |
1959年 | 28篇 |
1958年 | 49篇 |
1957年 | 39篇 |
1956年 | 44篇 |
1955年 | 31篇 |
1954年 | 25篇 |
1948年 | 32篇 |
排序方式: 共有3610条查询结果,搜索用时 0 毫秒
991.
A pigment-binding protein essential for regulation of photosynthetic light harvesting 总被引:58,自引:0,他引:58
Photosynthetic light harvesting in plants is regulated in response to changes in incident light intensity. Absorption of light that exceeds a plant's capacity for fixation of CO2 results in thermal dissipation of excitation energy in the pigment antenna of photosystem II by a poorly understood mechanism. This regulatory process, termed nonphotochemical quenching, maintains the balance between dissipation and utilization of light energy to minimize generation of oxidizing molecules, thereby protecting the plant against photo-oxidative damage. To identify specific proteins that are involved in nonphotochemical quenching, we have isolated mutants of Arabidopsis thaliana that cannot dissipate excess absorbed light energy. Here we show that the gene encoding PsbS, an intrinsic chlorophyll-binding protein of photosystem II, is necessary for nonphotochemical quenching but not for efficient light harvesting and photosynthesis. These results indicate that PsbS may be the site for nonphotochemical quenching, a finding that has implications for the functional evolution of pigment-binding proteins. 相似文献
992.
Identification of the Nogo inhibitor of axon regeneration as a Reticulon protein 总被引:105,自引:0,他引:105
Adult mammalian axon regeneration is generally successful in the peripheral nervous system (PNS) but is dismally poor in the central nervous system (CNS). However, many classes of CNS axons can extend for long distances in peripheral nerve grafts. A comparison of myelin from the CNS and the PNS has revealed that CNS white matter is selectively inhibitory for axonal outgrowth. Several components of CNS white matter, NI35, NI250(Nogo) and MAG, that have inhibitory activity for axon extension have been described. The IN-1 antibody, which recognizes NI35 and NI250(Nogo), allows moderate degrees of axonal regeneration and functional recovery after spinal cord injury. Here we identify Nogo as a member of the Reticulon family, Reticulon 4-A. Nogo is expressed by oligodendrocytes but not by Schwann cells, and associates primarily with the endoplasmic reticulum. A 66-residue lumenal/extracellular domain inhibits axonal extension and collapses dorsal root ganglion growth cones. In contrast to Nogo, Reticulon 1 and 3 are not expressed by oligodendrocytes, and the 66-residue lumenal/extracellular domains from Reticulon 1, 2 and 3 do not inhibit axonal regeneration. These data provide a molecular basis to assess the contribution of Nogo to the failure of axonal regeneration in the adult CNS. 相似文献
993.
The LIM homeobox gene Lhx9 is essential for mouse gonad formation 总被引:14,自引:0,他引:14
Birk OS Casiano DE Wassif CA Cogliati T Zhao L Zhao Y Grinberg A Huang S Kreidberg JA Parker KL Porter FD Westphal H 《Nature》2000,403(6772):909-913
994.
995.
Functional diversity governs ecosystem response to nutrient enrichment 总被引:10,自引:0,他引:10
The relationship between species diversity and ecosystem functioning is a central topic in ecology today. Classical approaches to studying ecosystem responses to nutrient enrichment have considered linear food chains. To what extent ecosystem structure, that is, the network of species interactions, affects such responses is currently unknown. This severely limits our ability to predict which species or functional groups will benefit or suffer from nutrient enrichment and to understand the underlying mechanisms. Here our approach takes ecosystem complexity into account by considering functional diversity at each trophic level. We conducted a mesocosm experiment to test the effects of nutrient enrichment in a lake ecosystem. We developed a model of intermediate complexity, which separates trophic levels into functional groups according to size and diet. This model successfully predicted the experimental results, whereas linear food-chain models did not. Our model shows the importance of functional diversity and indirect interactions in the response of ecosystems to perturbations, and indicates that new approaches are needed for the management of freshwater ecosystems subject to eutrophication. 相似文献
996.
Pervasive density-dependent recruitment enhances seedling diversity in a tropical forest 总被引:2,自引:0,他引:2
Negative density-dependent recruitment of seedlings, that is, seeds of a given species are less likely to become established seedlings if the density of that species is high, has been proposed to be an important mechanism contributing to the extraordinary diversity of tropical tree communities because it can potentially prevent any particular species from usurping all available space, either in close proximity to seed sources or at relatively larger spatial scales. However, density-dependent recruitment does not necessarily enhance community diversity. Furthermore, although density-dependent effects have been found at some life stages in some species, no study has shown that density-dependent recruitment affects community diversity. Here we report the results of observations in a lowland, moist forest in the Republic of Panamá in which the species identities of 386,027 seeds that arrived at 200 seed traps were compared with the species identities of 13,068 seedlings that recruited into adjacent plots over a 4-year period. Across the 200 sites, recruit seedling diversity was significantly higher than seed diversity. Part of this difference was explained by interspecies differences in average recruitment success. Even after accounting for these differences, however, negative density-dependent recruitment contributes significantly to the increase in diversity from seeds to seedling recruits. 相似文献
997.
1 Introduction1 Bioinformatics is a rapidly expanding field involving a significant contribution from the data mining community. Many different problems are grouped into the general category of bioinformatics, including protein secondary structure prediction, drug discovery, DNA microarray analysis, gene prediction and genome analysis [17]. In this paper, we focus on two particular problems in which data mining can contribute: drug discovery and protein secondary structure prediction. Both … 相似文献
998.
Dimeric tRNA precursors in yeast 总被引:23,自引:0,他引:23
999.
1000.
Zusammenfassung «Mounting behaviour» bei Ratten wird nicht nur durch die Kombination Testosteron plus Parachlorphenylalanin hervorgerufen. Auch durch die Gabe von Testosteron in Kombination mit den Substanzen Mesorgydin, WA 335-BS und Methysergid, die unter anderem antiserotonergen Effekt haben, wird «mounting behaviour» bei männlichen Ratten ausgelöst. Aufgrund dieser Ergebnisse und zitierten Beobachtungen ist eine ursächliche Bedeutung zwischen dem Anti-Serotonin-Effekt und der Aktivierung des «mounting behaviour» bei männlichen Ratten anzunehmen. Die spezifische Wirkung der Substanz PCPA allein kann für dieses Verhalten nicht verantwortlich gemacht werden. 相似文献