Research at channel level on the effect of LaCl3 on Radish (Raphanus satirus L.) vacuolar membrane

We recorded slow vacuolar (SV-type) channel currents of Radish vacuoles successfully for the first time by using the whole-vacuolar patch-clamp recording mode. SV- type currents would increase and threshold potentials of activation would shift towards more negative values with the increase of concentrations of cytosolic Ca²⁺. When 2.5 mmol/ L LaCl₃ and 4 mmol/L EGTA were added to bath solutions, SV-type currents were suppressed remarkably. Then adding LaCl₃ with different concentrations to pipette solutions, we found that LaCl₃ with higher concentrations (＞4 ´ 10^-7 mol/L) had a strong inhibitory effect on SV-type currents, while LaCl₃ with lower concentrations (≤4 ´ 10^-7 mol/L) promoted channel currents. This promoting effect provides an important basis at channel level for researching further the effects of rare earth on physiological activities of plants and the production-increase effects of rare earth fertilizers on crops.     

大同市公共图书馆现状及发展对策

阐述了大同市的市、区(县)两级公共图书馆的现状，从经济发展、政府投入等方面分析了大同市公共图书馆事业发展存在的问题及其原因，并提出了今后的发展方向。     

丝素蛋白在组织工程中的应用

丝素蛋白作为一种具有优良生物相容性的天然高分子材料在生物医用领域有着广泛的应用，着重阐述了丝素蛋白在组织工程领域中应用研究的最新进展。     

低氧对复合培养的肺微血管内皮细胞生长的作用

研究低氧对复合培养的肺微血管内皮细胞（LMVEC）生长的作用。用低氧气体（3％O2）处理复合培养的LMVEC细胞;流式细胞仪检测细胞的周期。在常氧或低氧条件下,LMVEC复合培养组G1期和S期细胞增多,G2／M期细胞显减少（P＜0.01,分别与单独培养组比较）;低氧单独培养组G1期细胞显减少,G2／M期细胞增多（P＜0.01,与常氧单独培养组比较）;低氧复合培养组G1期和DNA合成期（S期）细胞增多,G2／M期细胞减少（P＜0.01,与常氧复合培养组比较）。可见,低氧能促进单独或复合培养的LMVEC的增殖,复合培养的LMVEC比单独培养组增殖降低。     

Association analyses identify multiple new lung cancer susceptibility loci and their interactions with smoking in the Chinese population

To find additional susceptibility loci for lung cancer, we tested promising associations from our previous genome-wide association study (GWAS) of lung cancer in the Chinese population in an extended validation sample size of 7,436 individuals with lung cancer (cases) and 7,483 controls. We found genome-wide significant (P < 5.0 × 10(-8)) evidence for three additional lung cancer susceptibility loci at 10p14 (rs1663689, close to GATA3, P = 2.84 × 10(-10)), 5q32 (rs2895680 in PPP2R2B-STK32A-DPYSL3, P = 6.60 × 10(-9)) and 20q13.2 (rs4809957 in CYP24A1, P = 1.20 × 10(-8)). We also found consistent associations for rs247008 at 5q31.1 (IL3-CSF2-P4HA2, P = 7.68 × 10(-8)) and rs9439519 at 1p36.32 (AJAP1-NPHP4, P = 3.65 × 10(-6)). Four of these loci showed evidence for interactions with smoking dose (P = 1.72 × 10(-10), P = 5.07 × 10(-3), P = 6.77 × 10(-3) and P = 4.49 × 10(-2) for rs2895680, rs4809957, rs247008 and rs9439519, respectively). These results advance our understanding of lung cancer susceptibility and highlight potential pathways that integrate genetic variants and smoking in the development of lung cancer.     

六味地黄颗粒流动性的测定及评价

目的：测定六味地黄颗粒的休止角,评价润滑剂及其用量对颗粒流动性的影响。方法：采用注入法测定休止角。结果：六味地黄颗粒中加入滑石粉后测得平均休止角为50.582±4.929,用量为40.3%时的休止角为45.74±0.735 0;加入硬脂酸镁后测得平均休止角为49.24±1.718,用量为0.045%时的休止角为47.94±0.369 6;加入1.61%滑石粉∶硬脂酸镁（5∶1）的休止角为49.95±1.786。结论：六味地黄颗粒中可以用0.045%硬脂酸镁作为润滑剂,用1.61%的滑石粉∶硬脂酸镁（5∶1）则更好。     

桩基断桩成因分析及处理--G312线徐-界段K2319+487永登庄浪河大桥

结合G312线徐-界段兰州永登庄浪河大桥钻孔灌注桩基础施工,对钻孔灌注桩基础断桩的成因进行了详细的分析,简明扼要的论述了断桩的处理措施、方案和理论计算方法.     

64QAM信号的相位透明LEE氏纠错编码

首先介绍了 L EE氏码对相位透明的多进制线性纠错码的性质 ,然后将它克服解调载波恢复相位模糊的应用从 PSK推广到 6 4QAM系统 ,并给出性能比较分析结果。     

4，4′—联噻唑衍生物配合物的合成、表征及抗菌性研究

用自行制备的2,2′－二（对氯苯甲酰肼基）－4,4′－联噻唑（L3）和2,2′-二（邻氯苯甲酰肼基）－4,4′－联噻唑（L4）帮配体,合成了它们的Ni(Ⅱ）配合物。配合物的组成和结构已由元素分析、红外光谱和核磁共振谱所表征,并对它们进行了抗菌活性研究。     

一种等值线图绘制算法及其并行实现

提出了一种基于二次等参单元的等值线图绘制的并行算法,该算法根据有限元法将整个区域分割成多个互相连接的二次等参单元,通过并行生成每个等参单元的等值线,进而生成整个区域内的等值线,结果表明,在保证精度的情况下,提高了计算效率。