战争舆情演化建模研究

在分析媒体传播效果、人际传播效果为影响战争舆情演化主体(个体)立场演变的主因基础上,采用自底向上的基于Agent的建模理论与方法对战争舆情演化复杂系统进行建模研究,详细描述了媒体Agent影响力以及个体Agent立场演化致因两类模型,给出了个体Agent立场演化依据以及规则,初步实现了某地区战争舆情演化模型原型系统,并进行了仿真实验与分析。结果表明,模型的建立为量化研究舆情演化问题提供了一种思路。     

一个基于沟通函数的谣言传播仿真模型

人际谣言传播过程中人与人之间的沟通以及个体的记忆是谣言传播的主要因素。引入了个体对瑶言态度的不确定性、谣言的重要性和模糊性等参数建立了个体间的沟通函数,以此力基础实现了一介基于有限记忆的人际谣言传播的Agent仿真模型。仿真结果表明：谣言内容的重要性和模糊性、人际间的信任程度以及个体传播谣言的倾向概率以及个体基于有限记忆的态度选择是形成谣言及传播的重要因素。此结果能够与社会学、传播学对谣言形成与传播的研究结果相印证,反映了模型的合理性和有效性。     

带钢连续退火温度场数值模拟及其再结晶规律研究

利用有限元软件建立几何模型和有限元模型,对42CrMo带钢高温连续退火温度场进行数值模拟,通过稳态条件下带钢温度及再结晶软化率随时间变化规律的计算,研究非稳态条件下再结晶软化率随时间变化的关系。     

Cinobufacini-induced HeLa cell apoptosis enhanced by curcumin

When used in combination with certain chemotherapies, curcumin has been shown to increase apoptosis in several cancer cell lines. Here, we report the combined effects of curcumin and cinobufacini on human cervical carcinoma cells. The aim of this study was to examine whether curcumin could enhance apoptosis induced by cinobufacini. 3-(4,5-Dimethylthiazol-2-y1)-2,5- diphenytetrazolium bromide (MTT) assays revealed that the growth and proliferation of HeLa cells could be inhibited by 75% after a combined treatment of 25 μg/mL cinobufacini and 8 μg/mL curcumin. The combined treatment is 3 times more effective than treatment with 25 μg/mL cinobufacini alone. Annexin V-FITC/PI staining, morphological changes and immunofluorescence verified a significant enhancement in cinobufacini-induced apoptosis when cells were also exposed to curcumin. The data showed that the proportion of early apoptotic cells significantly increased from 15.43% in cells treated only with 25 μg/mL cinobufacini to 49.2% in cells treated with 25 μg/mL cinobufacini and 8 μg/mL curcumin. Moreover, compared with treatment of only 25 μg/mL cinobufacini, ROS production increased 1.7-fold, the intracellular free Ca 2+ concentration increased 1.5-fold, and the mitochon- drial membrane potential decreased by 20% in the combined treatment. Simultaneously, the atomic force microscopy (AFM) re- sults suggest that cells treated with a combination of cinobufacini and curcumin varied significantly in shape and ultrastructure. Collapsed cells with leaking cytoplasm, blebbing pores and emerging apoptotic bodies were prevalent. The nanoparticle size increased from 70 nm when the cells were treated with 25 μg/mL cinobufacini to 190 nm when the cells were treated with 25 μg/mL cinobufacini and 8 μg/mL curcumin. The size increase resulted in the cell membrane becoming considerably rough. These results can improve our understanding of combination treatments. Specifically, the combination of cinobufacini and curcumin may potentially find use as a novel cervical carcinoma treatment. Additionally, AFM is a powerful tool that can be used to explore cellular morphologies and ultrastructures.     

Alteration of the specificity ofPst I restriction endonuclease

The influence of factors on the substrate-specificity ofPst I restriction endonuclease has been studied with the method of electrophoresis. The results show that, the specificity ofPst I almost can not be influenced by the single alteration of the concentration of Tris·HCl, Mg²⁺ or Na⁺ in the reaction system, but it can be altered by the reduction of any two of them. The specificity can not be altered by the single alteration of pH or the replacement of Mg²⁺ with Mn²⁺. The addition of glycerol or dimethylsulphoxide (DM-SO) to the reaction system results in the relaxation of the substrate-specificity ofPst I, but dimethyl-methylformide, glycol and ethyl alcohol can not bring about the alteration ofPst I specificity. Through the method of cloning and sequencing, the nucleotides of No. 1 and 6 in the recognition sequence ofPst I have changed (1C→A or 6G→T). Used with the enzyme analysis of an artificially synthetic DNA segment containing a special sequence, the nucleotides of No. 1 and 6 have both changed (1C→A and 6G→T). The recognition sequence ofPst I is speculated to be changed from CTGCA→G to TGCA→. Foundation item: Supported by the Research Fund for the Doctoral Program of Higher Education. Biography: Zou Guo-lin (1947-), male, professor. research direction, biochemistry.     

Excel集成PHEES绘制水盐体系相图及模拟K2SO4生产工艺

利用Excel 97的VBA编程调用PHEES的单点固液相平衡计算模块,通过网格法绘制出Na+-K+-Cl--SO42--H2O的25℃和100℃下的相图和等水线图.并设计无机盐工艺模拟程序,模拟了K2SO4生产的一种两段法工艺.     

基于有限元数值模拟的直流电阻率激电找矿探测技术

为提高直流电阻率激电探测成果地质解释准确性,促进直流电阻率激电在找矿勘查中的应用,采用有限元数值模拟对直流电阻率激电探测中低阻高极化体、直立板状体、低阻盖层、高阻盖层、地表不均匀体、地形起伏及实测数据反演解释几个主要方面进行了对比分析。研究结果表明,对于实际勘查中的反演解释结果,根据异常特征构建地质体模型并进行有限元数值模拟,能快速判别探测目标体异常属性、区分虚假异常,提高定量解释水平及找矿勘查效率。研究结果为直流电阻率激电找矿探测定量解释提供了参考。     

多智能体涌现生成的群体行为仿真

众多实验表明,以建模仿真的方法研究复杂的群体行为是一条可行有效的途径.针对如何使所构建的群体行为模型在仿真过程中,既能表现自主、智能的个体行为,又能表现灵活、适应的整体行为,提出了一种基于智能体的综合建模方法,重点从信息获取、决策判断、运动控制三个方面对智能体模型的设计与实现进行了论述,并以实验结果证明了多智能体在交互.协调作用下涌现生成可视化群体行为仿真的科学性及合理性.     

海南岛农业干旱综合监测研究

采用遥感信息与地面气象观测数据相结合的方法进行农业干旱监测研究.选择适合高植被覆盖区旱情监测的标准化植被供水指数及适合热带气候区旱情监测的综合降水距平指数作为参数,通过与同步实测土壤含水量的数据融合构建农业干旱综合指数模型.用检验样点的实测数据对模型进行精度验证与实用性评价,检验结果显示均方根误差RMSE为4.65％,相对均方根误差RMSE,为19.28％,说明该模型具有较高的精度,可以用来监测海南岛的农业干旱.利用模型对海南岛2004年10月至2005年1月旱情进行监测与分析.结果表明海南岛旱情西部重于东部、北部重于南部、四周平原重于中部山区.2004年10月上旬起旱情持续加重,12月上旬达到旱情高峰,12月中旬旱情略有缓解,但直至监测末期2005年1月下旬旱情依然严重.旱情随着海拔、坡度减小而加重的趋势明显;平地旱情比坡地重,旱情随坡向的分异不是很明显.     

基于决策空间划分模型的多目标进化算法

为有效利用决定空间中的信息、提高收敛速度与准确度,提出了基于决策空间划分模型的多目标进化算法.该算法将决策空间划分成多个子决策空间并在每个子决策空间内映射出一个超球体,运用某一多目标进化算法完成超球体内个体的1轮次进化,基于粒子群优化算法的粒子移动机制实现超球体间的信息共享、引导超球体质心向最优解集方向移动.对8个测试问题的实验结果表明:基于决策空间划分模型的多目标进化算法在收敛精度和收敛稳定性方面比FastPGA,MOCell,NSGA-Ⅱ和SPEA2算法表现出更好的性能.