一种新型实用热轧工艺参数模型的开发

介绍了一套自主开发的热轧工艺参数模型. 该模型内耦合了不同钢种的变形抗力曲线,这些变形抗力方程中耦合了钢的化学成分、温度、应变、应变速率及奥氏体晶粒尺寸等因素. 根据输入的工艺参数用西姆斯方程计算每道次的应变速率及应变量,并得到相应道次的变形抗力、热轧轧制力、力矩及功率等参数. 模型可根据实测的结果自学习,并修正相应的结果. 与攀钢热轧厂的实测结果相比,模型的输出结果吻合较好,预测误差在10%以内.     

残肢与接受腔的三维有限元动态分析

以小腿残肢为研究对象，建立了残肢与接受腔三维有限元模型．根据行走过程中残肢与接受腔的动态边界条件，对残肢在一个步态周期内的5个典型步态时相进行了动态受力分析．结果表明，残肢的受力主要分布在髌韧带、胫骨内突、胫骨前脊、胫骨远端、腓骨头及腓骨远端．有限元动态分析较精确地分析了残肢在行走中的受力情况，克服了静态分析不能模拟残肢随步态变化的受力情况的局限性，为假肢接受腔的优化提供了科学的设计依据．     

基于正交试验的迷宫流道灌水器参数化设计研究

采用正交试验设计方法，取三角形迷宫流道灌水器的关键参数为因素，利用光固化快速成形技术制作出各参数组合的灌水器与外管一体化结构原型，并进行了灌水器水力性能的试验研究．流量和流态指数的极差和方差分析结果均显示出流道转角对流态指数的影响最显著，而流道单元数对灌水器流量的影响最大，这一结果有助于解决流道经优化后带来的流量增大问题．应用多元线性回归法拟合出灌水器流量系数和流态指数与参数的关系式，进而得到了流量与压力的回归方程．验证试验结果表明，回归方程能较好地预测迷宫流道灌水器流量与压力的关系，从而实现了灌水器参数化的结构设计．     

Influence factor of diesel soot formation in diesel engine combustion predicted by multistep soot model with highlight in soot surface activity

As more strict regulations on soot emission with increasing emphasis on the emitted soot particle size have been imposed, diesel engine partially premixed combustion had been proven to achieve ultra-low NOx and soot emissions with high thermal efficiency simulta- neously, by synergy control of mixing and chemical parameters. It calls for further study in the effect of com- bustion boundaries on soot formation. In this study, soot formation characteristic was investigated by CFD code coupled with reduced n-heptane model and improved multistep soot model. History of acetylene, which is taken as the main species of PAH formation and soot surface growth, plays more important roles on soot prediction. The revised parameter of fraction of active sites αCH was introduced as the indicator of soot surface activity in diesel soot formation. The effects of combustion boundaries on soot surface activity and soot surface growth were explored in this study. When the mixture was quite homogeneous, lowered combustion temperature was the main factor for reduced soot formation due to the lowered specific surface growth rate RCH, in spite of ec/4 increasing slightly due to the slowed decay rate of surface activity. As the inhomo- geneity of the mixture was increased, more unburned hydrocarbons were produced, promoting the formation of acetylene and soot surface activity. It was the dominated reason for higher soot surface growth rate, resulted wors- ened engine-out soot. In addition, residual of CO in later combustion phase impeded the re-oxidation of soot.     

HBeAg induces the expression of macrophage miR-155 to accelerate liver injury via promoting production of inflammatory cytokines

Activation of Kupffer cells (KCs) induced that inflammatory cytokine production plays a central role in the pathogenesis of HBV infection. The previous studies from our and other laboratory demonstrated miRNAs can regulate TLR-inducing inflammatory responses to macrophage. However, the involvement of miRNAs in HBV-associated antigen-induced macrophage activation is still not thoroughly understood. Here, we evaluated the effects and mechanisms of miR-155 in HBV-associated antigen-induced macrophage activation. First, co-culture assay of HepG2 or HepG2.2.15 cells and RAW264.7 macrophages showed that HepG2.2.15 cells could significantly promote macrophages to produce inflammatory cytokines. Furthermore, we, respectively, stimulated RAW264.7 macrophages, mouse primary peritoneal macrophages, or healthy human peripheral blood monocytes with HBV-associated antigens, including HBcAg, HBeAg, and HBsAg, and found that only HBeAg could steadily enhance the production of inflammatory cytokines in these cells. Subsequently, miRNAs sequencing presented the up- or down-regulated expression of multiple miRNAs in HBeAg-stimulated RAW264.7 cells. In addition, we verified the expression of miR-155 and its precursors BIC gene with q-PCR in the system of co-culture or HBeAg-stimulated macrophages. Meanwhile, the increased miR-155 expression was positively correlation with serum ALT, AST, and HBeAg levels in AHB patients. Although MAPK, PI3K, and NF-κB signal pathways were all activated during HBeAg treatment, only PI3K and NF-κB pathways were involved in miR-155 expression induced by HBeAg stimulation. Consistently, miR-155 over-expression inhibited production of inflammatory cytokines, which could be reversed by knocking down miR-155. Moreover, we demonstrated that miR-155 regulated HBeAg-induced cytokine production by targeting BCL-6, SHIP-1, and SOCS-1. In conclusion, our data revealed that HBeAg augments the expression of miR-155 in macrophages via PI3K and NF-κB signal pathway and the increased miR-155 promotes HBeAg-induced inflammatory cytokine production by inhibiting the expression of BCL-6, SHIP-1, and SOCS-1.     

熵用于信息评价的进一步探讨

从三个不同角度分析了信息的内在特征, 定义了信息的灵敏度、信息的价值灵敏度和信息的准确度,为不同信息的比较提供了主要的参考指标．     

动梁式龙门机床的双驱同步控制系统建模

针对动梁式龙门双驱系统产生不同步误差的原因及机理进行了建模研究,提出了一种双驱动同步控制模型.其特色在于模型基于动力学理论分析,描述了双驱动两轴机械耦合特性及两轴摩擦力特性对于不同步误差的影响.为对所建模型进行验证,以动梁式龙门铣床DK-1200为例,测量机床匀速及S型加减速运动下的两轴不同步误差,并与Matlab/Simulink的模型仿真结果进行对比.结果表明,具两轴摩擦特性及机械耦合特性的双驱同步控制模型仿真结果与实测结果的相关系数达0.861 8,所建模型能够有效反映动梁式龙门机床双驱同步结构的运行状况,两轴机械耦合及摩擦力不同是解决双驱动不同步问题不可忽略的因素.     

风险因子的模糊综合评判法

第一部分对风险间的关系进行了研究，归纳和定义了风险之间的五种基本关系；第二部分介绍风险因子评价法，给出了风险的模糊综合评判算法，并通过一个例子说明算法的应用.     

决策分析中一类极大熵问题的求解算法与应用

提出了决策分析中一类极大熵问题的求解算法。与求解极大熵问题常采用的Lagrange数乘法相比, 此算法更加简便、省时, 不仅适用于决策分析, 而且对非线性规划中的基准点测试也有一定的参考价值。文章最后应用此算法对一个投资决策问题进行了求解。     

广西高校计算机等级考试管理系统的开发与应用

采用面向对象的快速原型法和原型渐进法，使用ＰｏｗｅｒＢｕｉｌｄｅｒ６．０等快速生成原型的软件工具开发广西高校计算机等级考试管理系统（ＭＣＴ）。系统设计有良好的可扩展性和可维护性，采用开发的推广应用方式，建立ＭＣＴ网站供软件新版本下载，提供针对性的技术保障服务，ＭＣＴ系统已在广西４２所学校和厅高教处使用５年，使广西高校计算机等级考试考务管理全面实现计算机化，提高了考务管理工作的质量和效率。