从河南师大图书馆近几年的发展谈图书馆文化建设

以河南师范大学图书馆近几年的发展为例,分析了读者服务工作和内部员工管理两个方面的问题,阐述了图书馆文化建设的内涵、重要性和应当关注的问题。     

Dynamical impact of anomalous East-Asian winter monsoon on zonal wind over the equatorial western Pacific

Abstract Zonal wind anomaly over the equatorial western Pacific plays an important role in the occurrence of ENSO. The mechanism to produce zonal wind anomaly over the equatorial western Pacific is studied in this paper. It is shown clearly that zonal wind anomaly over the equatorial western Pacific is closely related to the anomaly of EastAsian winter monsoon. Anomalous strong （weak） East-Asian winter monsoon can excite not only the westerly （easterly）anomaly over the equatorial western Pacific but also a cyclonic （an anticyclonic） circulation over the east of the Philippines. The above anomalous circulation results from dynamical impacts of anomalous pressure pattern due to the East-Asian winter monsoon. Because there is westward （eastward） pressure gradient over the equatorial western Pacific, i.e. there is αp/αx 〈 0 （〉 0）, during strong （weak） East-Asian winter monsoon.     

Structural basis for 5'-end-specific recognition of guide RNA by the A. fulgidus Piwi protein

RNA interference (RNAi) is a conserved sequence-specific gene regulatory mechanism mediated by the RNA-induced silencing complex (RISC), which is composed of a single-stranded guide RNA and an Argonaute protein. The PIWI domain, a highly conserved motif within Argonaute, has been shown to adopt an RNase H fold critical for the endonuclease cleavage activity of RISC. Here we report the crystal structure of Archaeoglobus fulgidus Piwi protein bound to double-stranded RNA, thereby identifying the binding pocket for guide-strand 5'-end recognition and providing insight into guide-strand-mediated messenger RNA target recognition. The phosphorylated 5' end of the guide RNA is anchored within a highly conserved basic pocket, supplemented by the carboxy-terminal carboxylate and a bound divalent cation. The first nucleotide from the 5' end of the guide RNA is unpaired and stacks over a conserved tyrosine residue, whereas successive nucleotides form a four-base-pair RNA duplex. Mutation of the corresponding amino acids that contact the 5' phosphate in human Ago2 resulted in attenuated mRNA cleavage activity. Our structure of the Piwi-RNA complex, and that determined elsewhere, provide direct support for the 5' region of the guide RNA serving as a nucleation site for pairing with target mRNA and for a fixed distance separating the RISC-mediated mRNA cleavage site from the anchored 5' end of the guide RNA.     

电路仿真分析中建立元件数学模型的新方法

电路仿真机辅助分析的精度取决于所用的各种电路元件等效模型的精度,而如何建立各种电路元件精确的等效模型同时又要满足机辅分析对自动黑盒建模的要求是ＥＣＡＤ技术面临的难题。本文采用数学方程的综合推导和伴随方程的进一步完善,从理论上解决这一难题。     

带支撑钢框架结构的抗风可靠度二阶分析

采用杆系———层间模型分析高层建筑带支撑钢框架结构的二阶随机风振响应问题。先用杆系模型分析形成了考虑二阶效应的结构刚度矩阵,然后用层间模型把整个结构简化成质点串,进而用等效线性化方法分析获得结构层间位移和速度、加速度的统计量,最后结合工程算例分析了二阶效应对结构风振响应统计量及其正常使用可靠度的影响。     

关于数学思想方法的探讨

本文对数学思想方法问题作了较为深入的探讨,提出了自己的见解,并用具体例子作了解释。     

浅议室内环境设计气氛的创造

对气氛的把握和创造是室内环境设计所面临的十分重要的课题。具体阐述了室内环境气氛的概念,并初步探讨了如何正确把握和创造室内环境设计气氛的几个问题。     

地榆黄连灌肠剂提取工艺

以盐酸小檗碱为指标,采用紫外分光光度法测定其含量,选取不同的乙醇浓度、乙醇量、煎煮时间、煎煮次数为考察因素,采用L₉（3⁴）正交试验法优选地榆黄连灌肠剂的醇提工艺。最佳工艺为10倍药材量的70%的乙醇,提取2次,每次提取1.5h。     

两类非线性三阶四点边值问题解的存在性

利用Leray-Schauder度理论,得到了非线性三阶微分方程x'=f(t,x,x',x″),t∈[0,1]分别满足下列四点边界条件x(0)=0,x'(0)=αx'(ξ),x'(1)=βx'(η)和x'(0)=αx'(ξ),x(1)=0,x'(1)=βx'(η)的两类边值问题解的存在性,并且作为应用给出了一个例子.     

无线电环境地图的冗余感知数据删除技术研究

移动群智感知(mobile crowd sensing,MCS)技术在无线电环境地图(radio environment map,REM)的数据收集系统中优势明显,具有良好的应用前景.但由于移动群智感知的时空相关性特点,感知数据中存在大量的冗余,造成了数据存储效率低与传输带宽消耗大的问题.针对此问题,提出一种基于感知数据综合差异度的无线电环境地图冗余数据删除技术.该技术通过计算感知数据之间的综合差异度,实现对无线电环境地图系统中感知数据的冗余检测与删除.为了验证所提技术的有效性,通过实验将该技术与传统的重复数据删除技术进行比较.实验结果表明,与传统的重复数据删除技术相比,所提出的技术在保证数据完整性的前提下,极大地提高了系统的存储效率,降低了数据传输过程中网络带宽的消耗.