An inverted continental Moho and serpentinization of the forearc mantle

Volatiles that are transported by subducting lithospheric plates to depths greater than 100 km are thought to induce partial melting in the overlying mantle wedge, resulting in arc magmatism and the addition of significant quantities of material to the overlying lithosphere. Asthenospheric flow and upwelling within the wedge produce increased lithospheric temperatures in this back-arc region, but the forearc mantle (in the corner of the wedge) is thought to be significantly cooler. Here we explore the structure of the mantle wedge in the southern Cascadia subduction zone using scattered teleseismic waves recorded on a dense portable array of broadband seismometers. We find very low shear-wave velocities in the cold forearc mantle indicated by the exceptional occurrence of an 'inverted' continental Moho, which reverts to normal polarity seaward of the Cascade arc. This observation provides compelling evidence for a highly hydrated and serpentinized forearc region, consistent with thermal and petrological models of the forearc mantle wedge. This serpentinized material is thought to have low strength and may therefore control the down-dip rupture limit of great thrust earthquakes, as well as the nature of large-scale flow in the mantle wedge.     

Demonstration of a Na+−K+−Mg2+ dependent ATPase in a preparation from hindgut and malpighian tubules of two species of insect

Zusammenfassung Die Präsenz einer charakteristischen Na⁺–K⁺-aktivierbaren ATPase (E.C. 3.6.1.3) wurde erstmals in einer mikrosomalen Fraktion des Enddarmes und der malpighischen Gefässe bei der WüstenschreckeScistocerca gregaria und der LaubheuschreckeJamaicana flava nachgewiesen.     

Comparative genomic analysis of three Leishmania species that cause diverse human disease

Leishmania parasites cause a broad spectrum of clinical disease. Here we report the sequencing of the genomes of two species of Leishmania: Leishmania infantum and Leishmania braziliensis. The comparison of these sequences with the published genome of Leishmania major reveals marked conservation of synteny and identifies only approximately 200 genes with a differential distribution between the three species. L. braziliensis, contrary to Leishmania species examined so far, possesses components of a putative RNA-mediated interference pathway, telomere-associated transposable elements and spliced leader-associated SLACS retrotransposons. We show that pseudogene formation and gene loss are the principal forces shaping the different genomes. Genes that are differentially distributed between the species encode proteins implicated in host-pathogen interactions and parasite survival in the macrophage.