Photoreceptor damage following exposure to excess riboflavin

Flavins generate oxidants during metabolism and when exposed to light. Here we report that the photoreceptor layer of retinas from black-eyed rats is reduced in size by a dietary regime containing excess riboflavin. The effect of excess riboflavin was dose-dependent and was manifested by a decrease in photoreceptor length. This decrease was due in part to a reduction in the thickness of the outer nuclear layer, a structure formed from stacked photoreceptor nuclei. These changes were accompanied by an increase in photoreceptor outer segment autofluorescence following illumination at 328 nm, a wavelength that corresponds to the excitation maxima of oxidized lipopigments of the retinal pigment epithelium.     

企业创新成长模式探析

实施《国家中长期科学和技术发展规划纲要（2006-2020年）》，建设创新型国家，是全面落实科学发展观．开创社会主义现代化建设新局面的重大战略举措．其核心就是把增强自主创新能力作为发展科学技术的战略基点，走具有中国特色创新道路，推动科学技术的跨越式发展。     

Homocysteine increases the synthesis of adrenomedullin in vascular fibroblasts of rats

Homocysteine (Hcy), a highly reactive sulfur- containing amino acid, is an intermediate product of methionine metabolism. Elevation of plasma Hcy has been widely studied as an independent risk factor for many cardiovascular diseases such as atherosclerosis, thrombosis, etc.[1]. Inherited hyperhomocysteinemia cases usually suffer from occlusion or thrombosis in arteries and large veins before the age of 20. Hyperhomocysteinemia significantly reduces the survival rate[2] and dilatation functi…     

Measuring radial Young’s modulus of DNA by tapping mode AFM

Based on tapping mode AFM imaging, a method was demonstrated to evaluate compression elasticity of single double-stranded DNA （dsDNA） molecules in the force region. With images under ambient conditions, Young＇s moduli of dsDNA in compression were calculated. Results demonstrated that Young＇s moduli of dsDNA can be simply deduced according to the proposed model. The method can also be used to evaluate the compression elasticity of similar soft nanomaterials.     

Wavelet Numerical Solutions for Weakly Singular Fredholm Integral Equations of the Second Kind

Daubechies interval wavelet is used to solve numerically weakly singular Fredholm integral equations of the second kind. Utilizing the orthogonality of the wavelet basis,the integral equation is reduced into a linear system of equations. The vanishing moments of the wavelet make the wavelet coefficient matrices sparse,while the continuity of the derivative functions of basis overcomes naturally the singular problem of the integral solution. The uniform convergence of the approximate solution by the wavelet method is proved and the error bound is given. Finally,numerical example is presented to show the application of the wavelet method.     

基于Gauss滤波的多媒体图像的可视化检索

基于图像的可视化特征的图像检索和查询，是当前多媒体系统的重要研究方向。对于基于图像局部匹配的检索，传统的模板匹配和区域分割方法只能在目标图像中检索非常相似的对象，对尺度或形状有较大变化的目标则难以得到满意的结果。提出了一种不依赖于模板匹配的方法——图像的多尺度高斯滤波表示，用于图像的特征提取和局部匹配，并在分布并行索引结构下实现了该方法的快速索引和搜索算法。实验表明，该方法能够在较大尺度和视角变化范围内，更有效地进行图像的特征提取和检索，对基于图像局部区域相似性的匹配能达到较好的效果。     

复合式防水板在隧道防排水施工中的应用

随着我国既有线铁路大面积提速改造及快速铁路、高速铁路的修建,一些新技术、新材料、新工艺时于隧道工程的设计理论和施工技术带来了新的挑战,同时在许多方面深化和改革了传统的设计思路和施工方法.目前运营铁路中,隧道渗漏水已逐渐成为危及铁路行车安全的一大病害,隧道防排水工作已越来越受到建设、设计、施工、运营等单位的高度最视.文章着重介绍了隧道防排水施工中复合式防水板的应用及施工注意事项.     

碱提法回收猪骨蛋白质的探讨

对碱提法回收猪骨蛋白质工艺参数的研究表明，4种工艺参数对蛋白质得率均有不同程度的影响。其顺序为浸提液pH＞浸提时间＞沉降pH＞浸提温度。碱提法回收猪骨蛋白质的最高得率为25．7％，最佳工艺参数为浸提时间105min，浸提液pH12．0，浸提温度30℃和沉降pH5．0。     

壮族中小学生身体形态和机能发育状况分析

对１９８５－１９９５年广西７－１８岁城乡男女壮族学生身体形态，机能的动态分析结果表明：形态生长发育水平有了较大提高体格发育速度较快；肺活量水平有所提高；身体发育的匀称度有一定改善。在生长发育状况上城乡存在着明显差异。主要形态指标身高，体重和胸围每１０年平均增长值多数明显落后于全国同期水平，使原有的差距再拉大。