HPLC法同时测定灌胃补肾通络方大鼠血浆中马钱苷、阿魏酸和二苯乙烯苷含量

目的:建立灌胃补肾通络方大鼠血浆中马钱苷、阿魏酸和二苯乙烯苷的含量测定方法.方法:以甲醇-乙酸乙酯(V甲醇∶V乙酸乙酯=3∶1)提取处理血浆,氮气吹干后流动相复溶进样.色谱条件:Johnson spherigel C18柱(250 mm×4.6 mm,5μm);流动相:甲醇-0.01%乙酸水溶液,梯度洗脱;检测波长:马钱苷为235 nm,阿魏酸和二苯乙烯苷为320 nm;流速:1 m L/min;柱温:30℃;进样量:10μL.结果:空白血浆中内源性物质不干扰样品的测定.马钱苷、阿魏酸和二苯乙烯苷分别在0.03~3.00,0.03~3.00和0.02~2.00 mg/L范围内均有良好的线性关系(r≥0.999),检测限依次为0.020,0.015和0.010 mg/L;提取回收率分别大于79%、74%和58%,日间、日内精密度(RSD)均分别小于10%,7.3%和9.7%.结论:所建立的含量测定方法操作简便,灵敏,准确,适用于大鼠灌胃补肾通络方后血浆中马钱苷、阿魏酸和二苯乙烯苷的同时测定,为补肾通络方中有效成分药动学研究提供参考.     

砂岩储层酸化智能复合酸液体系研究及应用

常规砂岩酸化为了实现有效解堵,必须采用前置液、处理液和后置液多段液体,其作业程序复杂,研制出一套 智能复合酸液体系InteAcid。该酸液能替代常规砂岩酸化的多段酸液,实现单步酸化,显著简化作业程序,特别适 合于海上酸化作业。室内实验表明,InteAcid 在溶解砂岩矿物和解除伤害的同时,能有效抑制二次沉淀,对金属氟化 物、氟硅/铝酸盐和金属氢氧化物沉淀抑制率可分别达到71.81%、70.51% 和78.59%;单步岩芯流动实验后,无伤害、轻 微伤害、重度伤害岩芯渗透率提高为原始渗透率的1.35 倍、3.60 倍和15.00 倍;酸处理后孔隙结构微观分析表明,该酸 液具有提高岩芯渗透率和稳定黏土作用,对岩石骨架破坏很小。该酸液现场单步酸化11 口注水井,成功率100%,效 果显著率达90%。     

醋酸酯淀粉／PVA复合泡膜材料的燃烧及热降解性能研究

用醋酸酯淀粉和PV A为主要原料,在其他助剂的作用下,制备了淀粉基泡沫材料,研究表明：PV A含量为30份时,泡沫材料的密度最小为02．61 g/cm3,此时,泡沫材料的泡孔分布均匀。氢氧化镁含量在20份时泡沫材料的垂直燃烧达到了V -0级,并且热稳定性好。     

长岩芯驱替中不同位置的相渗曲线计算

相对渗透率是一个解释多相不可压缩流体在多孔介质中流动的复杂影响的重要参数,以便校正达西单相流动
方程。但是影响相对渗透率的因素很多,如：流体饱和度、岩石物性、润湿性、历史饱和度（滞后效应）上覆压力、黏土
及颗粒含量、黏度、温度、表面张力、束缚水饱和度、驱替速度和末端效应等。利用桓冠仁、沈平平的均质岩芯一维渗
流相渗推导结果,考虑长岩芯驱替室内实验中一维岩芯排列的非均质性和长岩芯逐级调和排序的特点,利用Matlab 软
件拟合出逐级调和平均渗透率与岩芯累计长度的关系,并反求出绝对渗透率倒数与累计岩芯长度的关系,将关系式由
离散模型转化成连续模型,并代入一维均质相渗模型,利用WC 油田长岩芯驱替实验数据计算出长岩芯驱替过程中不
同位置的相对渗透率曲线,计算结果是可靠的。     

Synthesis of kalsilite from microcline powder by an alkali-hydrothermal process

The properties of aluminosilicate kalsilite have attracted the interest of researchers in chemical synthesis, ceramic industry, biofuels, etc. In this study, kalsilite was hydrothermally synthesized from microcline powder in a KOH solution. The microcline powder, rich in potassium, aluminum, and silicon, was collected from Mountain Changling in Northwestern China. The effects of temperature, time, and KOH concentration on the decomposition of microcline were investigated. The kalsilite and intermediate products were characterized by means of wet chemistry analysis, X-ray Diffraction (XRD), infrared spectrometry (IR), 29Si magic angle spinning nuclear magnetic resonance (29Si MAS NMR), 27Al MAS NMR, and scanning electron microscope (SEM). With increasing temperature, the microcline powder transforms into a metastable KAlSiO₄ polymorph before transforming further into pure kalsilite. A mixture of both kalsilite and metastable KAlSiO₄ polymorph is obtained when the hydrothermal reaction is carried out within 2 h; but after 2 h, kalsilite is the predominant product. The concentration of KOH, which needs to be larger than 4.3 M, is an important parameter influencing the synthesis of kalsilite.     

On-line spheroidization process of medium-carbon low-alloyed cold heading steel

Conventionally manufactured 35CrMo cold heading steel must undergo spheroidization annealing before the cold heading process. In this paper, different types of deformation processes with various controlled cooling periods were operated to achieve on-line spheroidal cementite using the Gleeble-3500 simulation technique. According to the measured dynamic ferrite transformation temperature (A_d3), the deformation could be divided into two types: low temperature deformation at 810 and 780℃; “deformation-induced ferrite transformation” (DIFT) deformation at 750 and 720℃. Compared with the low temperature deformation, the DIFT deformation followed by accelerated cooling to 680℃ is beneficial for the formation of spheroidal cementite. Samples subjected to both the low-temperature deformation and DIFT deformation can obtain granular bainite by accelerated cooling to 640℃; the latter may contribute to the formation of a fine dispersion of secondary constituents. Granular bainite can transform into globular pearlite rapidly during subcritical annealing, and the more the disperse phase, the more homogeneously distributed globular cementite can be obtained.     

产生尺寸可调局域空心光束的技术

产生尺寸可调的局域空心光束在捕获和操控不同尺度的微粒方面具有重要的应用价值.文中主要阐述轴棱锥透镜系统、新型组合正轴棱锥、液体轴棱锥、可拆式组合轴棱锥,以及聚焦多环空心高斯光束产生尺寸可调的局域空心光束的相关技术研究,并基于几何光学,波动光学理论对各种技术进行分析和总结.     

X光透镜在同轴X光位相成像中的应用

介绍了同轴X光位相成像的基本原理,说明了位相成像与普通吸收成像的区别;初步研究了X光透镜在位相衬度成像中的应用,利用整体会聚X光透镜将大焦斑光源汇聚为微焦斑,从而使出射的X光满足位相衬度成像所需的空间相干条件,得到了较好的实验结果,为进一步研究X光透镜在该领域的应用打下了基础.     

基于改进粒子群算法的轮胎模型参数两级辨识

为提高PAC89(Pacejka'89 tyre model)轮胎模型的辨识速度和辨识精度,采用加入自适应权重和自然选择性的粒子群算法,并将PAC89轮胎模型参数分为两级,依次进行辨识.以轮胎模型侧偏力曲线的辨识为例,轮胎模型中的刚度因子、形状因子、峰值因子、曲率因子、垂直和水平偏移率为一级参数,通过改进粒子群算法进行一级辨识得到;组成上述因子的特性参数为二级参数,通过改进粒子群算法进行二级辨识得到.一级辨识收敛时的迭代次数小于40,二级辨识收敛时的、迭代次数在100左右,通过实验数据与辨识模型的对比得出平均相对残差为1.6961％.辨识结果表明,采用改进粒子群算法分两级对PAC89轮胎模型进行辨识的方法,能够在保证模型精度的同时提高辨识速度,是一种有效的多参数辨识方法.     

ZJ116A型卷接机组异物烟条剔除气路的改进设计

为解决在剔除空气压力变化的情况下,ZJ116A型卷接机组漏剔含异物烟条的问题,对剔除气路重新进行设计,使前道剔除气路距离缩短了80.8％,后道剔除气路距离缩短了82.4％.对改进前后的ZJ116A型卷接机组进行异物投放试验,结果表明:当剔除压力由3.0 bar降到2.5 bar后,改进前机组剔除含异物烟条的准确率由10...