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Summary 1. In mice,reserpine (5 mg/kg) causes a long-lasting depletion of the brain for -aminobutyric acid (GABA), which corresponds temporally to the lowered seizure threshold (electroshock).2.Iproniazid prohibits both the depletion of GABA and the lowering of seizure threshold.3. Relations between amine- and GABA-metabolism of the brain are pointed out. 相似文献