一类分数阶比率依赖型捕食系统的动力学分析

讨论了一类食饵带有疾病的分数阶比率依赖型捕食系统的动力学行为.利用线性化方法定性分析了各类平衡点的稳定性,并给出了其正平衡点局部渐近稳定的充分条件.数值模拟显示,参数和阶数对平衡点的收敛速度及其稳定性产生很重要的影响.     

猪附红细胞体形态特征的光镜和电镜观察

对猪附红细胞体(Ep ery throzoon su is)临床疑似病例和阳性感染手术摘脾猪血样中的病原形态进行的光镜和电镜观察。结果表明E.su is的形态近球形,直径在0.3~1.5μm之间,姬姆萨染色为紫红色圆点状,调节微调后有时可看到周围有淡蓝色的环绕,形似环形。阳性感染猪在摘除脾脏后第5 d出现明显的菌血症,红细胞的感染率18%~60%之间波动。临床疑似病例中只有部分血样为E.su is感染阳性,大部分为阴性;通过对E.su is外周血检查的不同方法进行比较,认为鲜血压片检查不适合作为E.su is感染的病原检查方法,采用血片的姬姆萨染色检查法时应以形态正常的红细胞上看到E.su is作为病原确诊的依据。     

Design and validation of wireless acceleration sensor network for structural health monitoring

0IntroductionCivil engineeringstructures suffer damages caused byenvironmental loads,fatigue,caustic effect and materialaging;thus,their strength reduces inevitably during theservice time.In order to assess these damages and makeappropriate decisions to keep the structures in good ser-vice,itis essential toimplement a damage detectionstrat-egy,and the process is referred to as structural healthmonitoring(SHM)[1].In an SHMsystem,a set of sen-sors are mountedinstructuresto measurethe structure…     

基于Pro／M对齿轮泵齿轮轴的精确建模和模态分析

以Pro／E为平台,依据方程精确建立齿轮泵的齿轮轴三维实体模型,并以振动力学和有限元理论为基础,建立齿轮轴的有限元模型,利用Pro／E集成环境Pro／MECHANJCA对其进行模态分析,计算出其前4阶固有阵型和固有频率,为齿轮泵的齿轮轴优化设计提供理论依据;为其动力响应的计算奠定了基础;为改善齿轮泵的动态特性、避免共振的发生、提高其工作的可靠性提供了一种方法。     

A genome-wide association study in Han Chinese identifies new susceptibility loci for ankylosing spondylitis

To identify susceptibility loci for ankylosing spondylitis, we performed a two-stage genome-wide association study in Han Chinese. In the discovery stage, we analyzed 1,356,350 autosomal SNPs in 1,837 individuals with ankylosing spondylitis and 4,231 controls; in the validation stage, we analyzed 30 suggestive SNPs in an additional 2,100 affected individuals and 3,496 controls. We identified two new susceptibility loci between EDIL3 and HAPLN1 at 5q14.3 (rs4552569; P = 8.77 × 10(-10)) and within ANO6 at 12q12 (rs17095830; P = 1.63 × 10(-8)). We also confirmed previously reported associations in Europeans within the major histocompatibility complex (MHC) region (top SNP, rs13202464; P < 5 × 10(-324)) and at 2p15 (rs10865331; P = 1.98 × 10(-8)). We show that rs13202464 within the MHC region mainly represents the risk effect of HLA-B*27 variants (including HLA-B*2704, HLA-B*2705 and HLA-B*2715) in Chinese. The two newly discovered loci implicate genes related to bone formation and cartilage development, suggesting their potential involvement in the etiology of ankylosing spondylitis.     

基于负荷率差别定价的分时输配电价优化模型

输配电价是电力市场改革的关键,是推进售电市场放开的重要基础.随着输配电价改革不断深入,不同类型的输配电价定价方法亟待研究.本文以大工业用户输配电价为研究对象,首先,引入汉森门槛模型,内生性划分大工业用户的负荷率区间;其次,建立输配电网长期增量成本分摊模型,提出基于负荷率差别的输配电价定价方法,并借鉴分时电价思想,构建基于负荷率差别定价的分时输配电价协调优化模型,设计分电压等级、计及负荷率差别的分时输配电价;最后,以我国中部H省大工业用户为例,验证所提模型可行性.研究结果表明,所提分时输配电价定价方法吸收了负荷率电价和分时电价优点,能够兼顾效率与公平,同时有效调节电力用户需求,实现削峰填谷,一定程度缓解输配电网阻塞问题.     

The utility F-box for protein destruction

A signature feature of all living organisms is their utilization of proteins to construct molecular machineries that undertake the complex network of cellular activities. The abundance of a protein element is temporally and spatially regulated in two opposing aspects: de novo synthesis to manufacture the required amount of the protein, and destruction of the protein when it is in excess or no longer needed. One major route of protein destruction is coordinated by a set of conserved molecules, the F-box proteins, which promote ubiquitination in the ubiquitin-proteasome pathway. Here we discuss the functions of F-box proteins in several cellular scenarios including cell cycle progression, synapse formation, plant hormone responses, and the circadian clock. We particularly emphasize the mechanisms whereby F-box proteins recruit specific substrates and regulate their abundance in the context of SCF E3 ligases. For some exceptions, we also review how F-box proteins function through non-SCF mechanisms.     

《细胞生物学》综合实验教学改革

通过对《细胞生物学》综合实验的教学改革,提高生物科学专业学生的科研创新意识。方法:在生物科学专业增设生物技术综合实验课程,以单克隆抗体实验为中心通过综合性、设计性实验培养学生发现问题、思考问题和解决问题的能力,提高了学生对科研的认识。结果:通过教学改革使学生对科研过程有基本的了解,在标书撰写、实验操作、论文写作方面均有提高。实验教学改革提高了学生的动手能力,能培养具有初步科研能力的生物专业人才。     

基于SAP的采购系统设计

本文以项目软件工程过程为基础,对系统进行调研,针对用户需求进行业务蓝图设计与系统分析,并依据设计理念进行系统测试与实现,进行项目实施及后续支持描述与优化.建立一个以加快响应速度、降低采购成本、提高经济效益为主要目的,基于SAP物料管理为主要内容的易于维护的采购平台.     

流媒体技术特点及其在现代教学模式中的作用探究

主要分析了四种流媒体格式的技术特点，并对流媒体技术在网络课程建设中的应用以及对建立新型教育教学模式的积极作用展开了探讨。