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901.
Angela M. Ortega-León Maricela Villagrán-Santa Cruz J. Jamie Zú?iga-Vega Raúl Cueva-del Castillo Fausto R. Méndez-de la Cruz 《西北部美国博物学家》2011,69(1)
Asynchronous reproduction is a common phenomenon in high-elevation populations of lizards from Central México. Sperm storage in the reproductive tract of females is the mechanism for making oocyte fertilization possible. Our study addresses questions related to functional oviductal sperm storage of females mating on different dates throughout the reproductive season. A population of Sceloporus mucronatus with copulation in the summer and ovulation in the fall was chosen for this experiment. Eleven females that copulated in the field during June and 13 females that copulated in captivity during August were maintained in the laboratory until parturition. The number of pregnant females and the litter sizes produced in each experimental group were indicative of the viability of the stored sperm. Sperm stored in the reproductive tract of females were able to fertilize eggs after 4 months. No significant differences were found in the number of pregnant females between the 2 experimental groups nor in the litter sizes that they produced. We found that the amount of time sperm were held in the female reproductive tract (ca. 3 months) had no effect on the capacity of sperm to fertilize eggs. Histological examination of 8 oviducts collected before the mating season eliminated the possibility of sperm storage from one year to the next. In this system, sperm retention could have evolved as a response mechanism to deal with the asynchrony between sexes in the reproductive cycles. However, we cannot rule out alternative hypotheses. 相似文献
902.
We translocated 196 Sage Grouse ( Centrocercus urophasianus into Sawtooth Valley, Idaho, during March-April 1986-87 to augment a small resident population. Forty-four grouse equipped with radio transmitters were monitored through spring and summer. Nest sites ( n = 6) had greater ( P = .032) horizontal cover than did independent random plots ( n = 7). During summer, grouse used sites ( n = 50) with taller live and dead shrub heights, greater shrub canopy cover, and more ground litter ( P n = 50) 50-300 m from use sites. Distance to edge and mountain sagebrush ( Artemisia tridentata vaseyana ) density best separated use sites from independent random plots in logistic regression analysis and correctly classified 64% of the use sites and 78% of the independent random plots. Sage Grouse used sties that had narrower frequency distributions for many variables than did independent plots ( P < .04), suggesting selection for uniform habitat. 相似文献
903.
Use of interstate highway overpasses and billboards for nesting by the common raven ( Corvus corax )
Common ravens are usually rather shy birds around their nests and avoid nesting too near human activity. We here report the use of overpasses along heavily traveled Interstate Highway 84 in Idaho and Utah for nest placement. Nests are within 6 m of passing vehicles. 相似文献
904.
905.
Five additional species of wood rotting basidiomycetes on Arizona junipers are described and illustrated. All cause a white rot of dead, fallen trees. Leptosporomyces juniperinus is proposed as a new species. Vararia fibra is reported from the United States for the first time. 相似文献
906.
Irina Tikhonenko Valentin Magidson Ralph Gräf Alexey Khodjakov Michael P. Koonce 《Cellular and molecular life sciences : CMLS》2013,70(7):1285-1296
The M-type kinesin isoform, Kif9, has recently been implicated in maintaining a physical connection between the centrosome and nucleus in Dictyostelium discoideum. However, the mechanism by which Kif9 functions to link these two organelles remains obscure. Here we demonstrate that the Kif9 protein is localized to the nuclear envelope and is concentrated in the region underlying the centrosome point of attachment. Nuclear anchorage appears mediated through a specialized transmembrane domain located in the carboxyl terminus. Kif9 interacts with microtubules in in vitro binding assays and effects an endwise depolymerization of the polymer. These results suggest a model whereby Kif9 is anchored to the nucleus and generates a pulling force that reels the centrosome up against the nucleus. This is a novel activity for a kinesin motor, one important for progression of cells into mitosis and to ensure centrosome-nuclear parity in a multinuclear environment. 相似文献
907.
908.
P.A. Bretscher N. Ismail J.N. Menon C.A. Power J. Uzonna G. Wei 《Cellular and molecular life sciences : CMLS》2001,58(12-13):1879-1896
The occurrence of infectious disease represents a failure of the immune system, a failure that must be prevented by effective vaccination or remedied by treatment. Vaccination against acute diseases such as smallpox and polio are very effective, due to the rapid and increased immune response of vaccinated individuals upon natural infection. In contrast, effective vaccination against intracellular pathogens that cause chronic diseases, such as the leishmaniases, tuberculosis and AIDS, has not been achieved. Clinical observations suggest cell-mediated, Th1 responses, exclusive of antibody production and the generation of Th2 cells, are optimally protective against these intracellular pathogens. Effective vaccination must ensure the generation of such a protective response. We explore here whether understanding very broad features of the regulation of the immune response can accommodate modern findings on the immunological features of these diseases, and provide a perspective within which strategies for effective vaccination and treatment can be developed. 相似文献
909.
In higher vertebrates, sulfatases belong to a conserved family of enzymes that are involved in the regulation of cell metabolism
and in developmental cell signaling. They cleave the sulfate from sulfate esters contained in hormones, proteins, and complex
macromolecules. A highly conserved cysteine in their active site is post-translationally converted into formylglycine by the
formylglycine-generating enzyme encoded by SUMF1 (sulfatase modifying factor 1). This post-translational modification activates all sulfatases. Sulfatases are extensively
glycosylated proteins and some of them follow trafficking pathways through cells, being secreted and taken up by distant cells.
Many proteoglycans, glycoproteins, and glycolipids contain sulfated carbohydrates, which are sulfatase substrates. Indeed,
sulfatases operate as decoding factors for a large amount of biological information contained in the structures of the sulfated
sugar chains that are covalently linked to proteins and lipids. Modifications to these sulfate groups have pivotal roles in
modulating specific signaling pathways and cell metabolism in mammals. 相似文献
910.