Bcl-2 maintains B cell memory

The number of lymphocytes in an animal is remarkably constant despite antigen-driven proliferation and a high rate of B-cell lymphopoiesis. This reflects the relatively brief lifespan of many newly generated B cells and argues for a well-regulated death mechanism. Even so, a secondary immune response can be generated years after a primary exposure to antigen. Antigen that might restimulate B cells persists for extended periods on follicular dendritic cells in the light zone of germinal centres. Antigen-binding B cells have also been found months after the end of obvious cell division. The precise signal that enables certain B cells to emerge as long-term surviving memory cells is unknown. Bcl-2, an inner mitochondrial membrane protein, blocks programmed cell death in B cells. We report here that this proto-oncogene maintains immune responsiveness. Transgenic mice overproducing Bcl-2 have a long-term persistence of immunoglobulin-secreting cells and an extended lifetime for memory B cells.     

论高校校园文化建设

高校校园化是社会主义化建设的重要组成部分，是高校思想政治工作的重要载体和提升学生综合素质的有效途径。本通过透析高校校园化的涵义、特征、功能，提出了推进校园化建设的新理念：即科学精神与人精神和谐相融。思想教育与素质培养结合并进。新时期深化高校校园化建设要以育人为宗旨，以大力加强校风、学风建设为核心，着力创新化活动的内容和形式，营造一种健康、理性、高品位的化精神氛围。     

Multi-baseline phase unwrapping algorithm for INSAR

A novel multi-baseline phase unwrapping algorithm based on the unscented particle filter for interferometric synthetic aperture radar(INSAR) technology application is proposed.The proposed method is not constrained by the nonlinearity of the problem and is independent of noise statistics,and performs noise eliminating and phase unwrapping at the same time by combining with an unscented particle filter with a path-following strategy and an omni-directional local phase slope estimator.Results obtained from multi-baseline synthetic data and single-baseline real data show the performance of the proposed method.     

超宽带在煤矿井下穿透障碍物杂波信号的抑制方法

传统的奇异值分解、主成分分析、独立成分分析等谱分析方法很难分离目标信号和杂波信号。根据煤矿井下杂波信号起伏较大的特点,利用经验模态分解与参考独立分量分析(ICAR)联合抑制超宽带在煤矿井下穿透障碍物杂波信号。仿真结果表明:改进的ICA-R方法抑制杂波效果显著,分离出的目标回波幅度得到提高,消除了杂波区域中起伏信号的影响。该方法可以抑制杂波对目标信号的影响,有效地分离出目标信号。     

Discovery of very-high-energy gamma-rays from the Galactic Centre ridge

The source of Galactic cosmic rays (with energies up to 10(15) eV) remains unclear, although it is widely believed that they originate in the shock waves of expanding supernova remnants. At present the best way to investigate their acceleration and propagation is by observing the gamma-rays produced when cosmic rays interact with interstellar gas. Here we report observations of an extended region of very-high-energy (> 10(11) eV) gamma-ray emission correlated spatially with a complex of giant molecular clouds in the central 200 parsecs of the Milky Way. The hardness of the gamma-ray spectrum and the conditions in those molecular clouds indicate that the cosmic rays giving rise to the gamma-rays are likely to be protons and nuclei rather than electrons. The energy associated with the cosmic rays could have come from a single supernova explosion around 10(4) years ago.     

卫生瓷产品设计CAD系统

本文详细阐述了卫生瓷产品设计 CAD系统开发的技术路线。其交互造型模块和参数化造型模块满足了不同设计的要求 ,而流道分析模块为设计出性能优良的产品提供了有力的保障。     

渐开线齿轮传动的振动分析研究

本文对齿轮由于变刚度啮合所产生的振动问题采用摄动方法进行分析．首次导出变刚度啮合齿轮副角动量守恒定理及相应的有阻尼和无阻尼两种情况下的摄动方程；并用离散富氏变换数值计算获得轮齿节点处的刚度、位移、速度、加速度以及相应的频谱．其结果不但为进一步进行齿轮噪声振动分析和疲劳寿命分析等提供了必要的理论根据及相应的计算方法；而且对齿轮工程设计有重要的参考价值．     

碱金属夹层对半导体异质结能带偏移的影响

用光电发射的方法研究了碱金属夹层对Ｇｅ和Ⅲ－Ⅴ族半导体异质结形成和能带偏移的影响．实验表明，价带偏移（ΔＥｖ）与夹层厚度有关．０．５ＭＬＣｓ和１ＭＬＮａ可使Ｇｅ／ＩｎＰ（１００）及Ｇｅ／ＧａＡｓ（１００）的ΔＥｖ的值分别增加０．２０ｅＶ和０．１８ｅＶ．碱金属与衬底相互作用而引起的界面偶极矩的改变是导致ΔＥｖ改变的主要原因．