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Norris BR Tuthill PG Ireland MJ Lacour S Zijlstra AA Lykou F Evans TM Stewart P Bedding TR 《Nature》2012,484(7393):220-222
An intermediate-mass star ends its life by ejecting the bulk of its envelope in a slow, dense wind. Stellar pulsations are thought to elevate gas to an altitude cool enough for the condensation of dust, which is then accelerated by radiation pressure, entraining the gas and driving the wind. Explaining the amount of mass loss, however, has been a problem because of the difficulty of observing tenuous gas and dust only tens of milliarcseconds from the star. For this reason, there is no consensus on the way sufficient momentum is transferred from the light from the star to the outflow. Here we report spatially resolved, multiwavelength observations of circumstellar dust shells of three stars on the asymptotic giant branch of the Hertzsprung-Russell diagram. When imaged in scattered light, dust shells were found at remarkably small radii (less than about two stellar radii) and with unexpectedly large grains (about 300 nanometres in radius). This proximity to the photosphere argues for dust species that are transparent to the light from the star and, therefore, resistant to sublimation by the intense radiation field. Although transparency usually implies insufficient radiative pressure to drive a wind, the radiation field can accelerate these large grains through photon scattering rather than absorption--a plausible mass loss mechanism for lower-amplitude pulsating stars. 相似文献
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Christopher Norris 《Foundations of Science》2000,5(1):3-45
In this essay I examine various aspects of the nearcentury-long debate concerning the conceptualfoundations of quantum mechanics and the problems ithas posed for physicists and philosophers fromEinstein to the present. Most crucial here is theissue of realism and the question whether quantumtheory is compatible with any kind of realist orcausal-explanatory account which goes beyond theempirical-predictive data. This was Einstein's chiefconcern in the famous series of exchanges with NielsBohr when he refused to accept the truth orcompleteness of a doctrine (orthodox QM) which ruledsuch questions to be strictly inadmissible. I discussthe later history of quantum-theoretical debate withparticular reference to the issue of nonlocality,i.e., the phenomenon of superluminal(faster-than-light) interaction betweenwidely-separated particles. Then I show how thestandard `Copenhagen' interpretation of QM hasinfluenced current anti-realist orontological-relativist approaches to philosophy ofscience. Indeed, there are clear signs that somephilosophers have retreated from a realist positionvery largely in response to just these problems. So itis important to ask exactly why – on what scientificor philosophical grounds – any preferred alternative(causal-realist) construal should have been ruled outas a matter of orthodox QM wisdom. Moreconstructively, my paper presents various arguments infavour of one such alternative, the `hidden-variables'theory developed since the early 1950s by David Bohmand consistently marginalised by proponents of theCopenhagen doctrine. 相似文献
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Recent Northern Hemisphere tropical expansion primarily driven by black carbon and tropospheric ozone 总被引:1,自引:0,他引:1
Observational analyses have shown the width of the tropical belt increasing in recent decades as the world has warmed. This expansion is important because it is associated with shifts in large-scale atmospheric circulation and major climate zones. Although recent studies have attributed tropical expansion in the Southern Hemisphere to ozone depletion, the drivers of Northern Hemisphere expansion are not well known and the expansion has not so far been reproduced by climate models. Here we use a climate model with detailed aerosol physics to show that increases in heterogeneous warming agents--including black carbon aerosols and tropospheric ozone--are noticeably better than greenhouse gases at driving expansion, and can account for the observed summertime maximum in tropical expansion. Mechanistically, atmospheric heating from black carbon and tropospheric ozone has occurred at the mid-latitudes, generating a poleward shift of the tropospheric jet, thereby relocating the main division between tropical and temperate air masses. Although we still underestimate tropical expansion, the true aerosol forcing is poorly known and could also be underestimated. Thus, although the insensitivity of models needs further investigation, black carbon and tropospheric ozone, both of which are strongly influenced by human activities, are the most likely causes of observed Northern Hemisphere tropical expansion. 相似文献
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The secreted protein Jelly belly (Jeb) is required for an essential signalling event in Drosophila muscle development. In the absence of functional Jeb, visceral muscle precursors are normally specified but fail to migrate and differentiate. The structure and distribution of Jeb protein implies that Jeb functions as a signal to organize the development of visceral muscles. Here we show that the Jeb receptor is the Drosophila homologue of anaplastic lymphoma kinase (Alk), a receptor tyrosine kinase of the insulin receptor superfamily. Human ALK was originally identified as a proto-oncogene, but its normal function in mammals is not known. In Drosophila, localized Jeb activates Alk and the downstream Ras/mitogen-activated protein kinase cascade to specify a select group of visceral muscle precursors as muscle-patterning pioneers. Jeb/Alk signalling induces the myoblast fusion gene dumbfounded (duf; also known as kirre) as well as org-1, a Drosophila homologue of mammalian TBX1, in these cells. 相似文献
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Apolactoferrin structure demonstrates ligand-induced conformational change in transferrins 总被引:14,自引:0,他引:14
Proteins of the transferrin family, which contains serum transferrin and lactoferrin, control iron levels in higher animals through their very tight (Kapp approximately 10(20)) but reversible binding of iron. These bilobate molecules have two binding sites, one per lobe, each housing one Fe3+ and the synergistic CO3(2-) ion. Crystallographic studies of human lactoferrin and rabbit serum transferrin in their iron-bound forms have characterized their binding sites and protein structure. Physical studies show that a substantial conformational change accompanies iron binding and release. We have addressed this phenomenon through crystal structure analysis of human apolactoferrin at 2.8 A resolution. In this structure the N-lobe binding cleft is wide open, following a domain rotation of 53 degrees, mediated by the pivoting of two helices and flexing of two interdomain polypeptide strands. Remarkably, the C-lobe cleft is closed, but unliganded. These observations have implications for transferrin function and for binding proteins in general. 相似文献
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Effect of nitrous oxide on the auditory evoked response in man 总被引:1,自引:0,他引:1
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Action spectra for bilirubin photodisappearance 总被引:1,自引:0,他引:1
D. A. Lightner T. A. Wooldridge S. L. Rodgers R. D. Norris 《Cellular and molecular life sciences : CMLS》1980,36(4):380-382
Summary The excitation wavelength dependence of bilirubin photodestruction, as measured by quantum yields, has been determined in benzene, chloroform-1% ethanol, chloroform-1% hexane, methanol-1% concentrated ammonia, pH 8.5 aqueous buffer and pH 7.4 aqueous buffer with added albumin. The results show that in the visible spectrum the 370–490 nm excitation wavelength region is very effective in the photodestruction, but excitation in the UV-region (<320 nm) is even more effective.The authors wish to thank the National Science Foundation (CHE 74-20877) and the National Institute of Child Health (HD 09026) for the generous support of this work. 相似文献
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