粒度组成对KR搅拌头用浇注料性能的影响

以Andreassen颗粒紧密堆积理论为基础,研究KR搅拌头外衬莫来石浇注料临界粒度和粒度组成对其密度、强度和热震稳定性的影响.结果表明,随着临界粒度的增大,浇注料干燥和烧结后冷态密度与强度均明显提高;临界粒度一定时,粒度组成对浇注料冷态密度、强度以及热震稳定性的影响基本一致,但临界粒度不同的浇注料试样达到最佳性能所对应的粒度组成并不完全相同;与冷态性能相比,浇注料热震稳定性受临界粒度的影响较小.     

热处理对以Al2O3为绝缘层的并五苯薄膜晶体管性能的影响

采用阳极氧化法制备了Al_2O_3绝缘材料,并制备了以Al_2O_3为绝缘层的并五苯薄膜晶体管器件(OTFT)。Al_2O_3绝缘层经过10 min 350℃氢热处理后,OTFT迁移率比未经氢热处理的增大近20倍,且阈值电压降到了-7 V。Al_2O_3膜MIS结构电容—电压(C–V)特性的平带电压平移量数据表明,Al_2O_3膜经过热处理后,并五苯半导体与Al_2O_3绝缘体界面处以及绝缘体内缺陷态密度显著地降低,Al_2O_3绝缘层和并五苯半导体层之间的接触得到改善,这使得经热处理Al_2O_3膜的OTFT器件性能得到显著的改善。     

HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS

A prominent feature of late-onset neurodegenerative diseases is accumulation of misfolded protein in vulnerable neurons. When levels of misfolded protein overwhelm degradative pathways, the result is cellular toxicity and neurodegeneration. Cellular mechanisms for degrading misfolded protein include the ubiquitin-proteasome system (UPS), the main non-lysosomal degradative pathway for ubiquitinated proteins, and autophagy, a lysosome-mediated degradative pathway. The UPS and autophagy have long been viewed as complementary degradation systems with no point of intersection. This view has been challenged by two observations suggesting an apparent interaction: impairment of the UPS induces autophagy in vitro, and conditional knockout of autophagy in the mouse brain leads to neurodegeneration with ubiquitin-positive pathology. It is not known whether autophagy is strictly a parallel degradation system, or whether it is a compensatory degradation system when the UPS is impaired; furthermore, if there is a compensatory interaction between these systems, the molecular link is not known. Here we show that autophagy acts as a compensatory degradation system when the UPS is impaired in Drosophila melanogaster, and that histone deacetylase 6 (HDAC6), a microtubule-associated deacetylase that interacts with polyubiquitinated proteins, is an essential mechanistic link in this compensatory interaction. We found that compensatory autophagy was induced in response to mutations affecting the proteasome and in response to UPS impairment in a fly model of the neurodegenerative disease spinobulbar muscular atrophy. Autophagy compensated for impaired UPS function in an HDAC6-dependent manner. Furthermore, expression of HDAC6 was sufficient to rescue degeneration associated with UPS dysfunction in vivo in an autophagy-dependent manner. This study suggests that impairment of autophagy (for example, associated with ageing or genetic variation) might predispose to neurodegeneration. Morover, these findings suggest that it may be possible to intervene in neurodegeneration by augmenting HDAC6 to enhance autophagy.     

基于信息平台整合对高职院校毕业设计过程监控信息化研究

随着社会的发展,信息技术的进步,教育信息化特别是实践教学信息化具有重要研究意义.基于地方信息平台的整合,提出了高职高专院校毕业论文(设计)过程监控网络信息化.先设计了毕业论文(设计)信息平台结构,从而把政、校、企对学生进行共同培养模式进行了有机的结合;再从出题、选题、论文答辩、论文成果转化等方面对毕业论文(设计)管理实现了信息化;通过理论分析与实践证明此信息化过程有一定的理论意义和实用价值.     

一种检测氯胺酮的新方法

目的:寻找检验氯胺酮的试剂。方法:用化学方法进行检验,根据颜色反应进行识别。结果:氯胺酮与硫氰酸钴混合溶液反应,出现了特征性的紫色沉淀物。结论:该方法具有操作简便,结果准确,特异性强,便于推广的优势,可用于氯胺酮的初步检验。     

基于深度贝叶斯网络学习的不确定性建模方法

战场态势评估涉及很多不确定因素,对不确定性进行仿真建模能够提高态势评估的能力。针对参战对象多元、不确定性增多导致的无法全面准确表达不确定性问题,提出了基于记忆模块和变分自编码器的深度贝叶斯网络模型。采用生成模型设计了基于深度贝叶斯网络学习的态势评估模型;阐述了融合记忆模块的深度生成模型原理和模型的学习与推理过程;以某空袭行动为例构建贝叶斯网络,对所提方法进行了验证。结果表明:深度神经网络能够逼近隐变量的非线性变换,设计的记忆模块能存储深度神经网络提取的大量局部特征,通过学习自动得到了贝叶斯网络条件概率,增强了不确定性建模能力。     

基于MSP430F5438A的工业排污督察管理终端设计

工业排污占环境污染高达70％,传统水质监测方法效率低且排污企业暗自偷排、突排污水问题严重,为此设计了一款基于MSP430F5438A和北斗的工业排污督察管理终端.工业排污督察管理终端以MSP430F5438A为核心控制器,利用北斗定位模块定位排污口位置并借助水质检测单元实时采集pH值、温度、浑浊度、溶解氧、氨氮浓度等信...     

海德格尔论意向性及其生命意蕴

意向性是海德格尔现象学思想的中心主题,也是通达存在问题的重要路径。海德格尔重点探究了意向性的三个方面,并诠释了其内含的生命意蕴。第一,意向性在本性上是实践,表现为此在操劳着的生命活动。第二,意向性的根基是超越性,是从此在的在世引申出来的,呈示出生命之投身于世界的原初状态。第三,意向性的渊源是时间性,时间性的绽出境域为意向性之何所指提供了源泉,也决定了生命的绽出境域。这一思想迸射出生命的灵性之光,是对僵固的科学理论和学院哲学的批判,对人们关注实际的生命经验、认识生命的价值和意义具有重要作用。     

Analysis for MIMO correlated frequency-selective channel in the presence of interference

The space time spreading, superimposed training sequences, and space-time coding are used to present a multiple input and multiple output （MIMO） systems model, and a closed-form of average error probability upper bound expression for MIMO correlated frequency-selective channel in the presence of interference （co-channel interference and jamming signals） is derived. Moreover, the correlation at both ends of the wireless link that can be incorporated equivalently into correlation at the transmit end is also derived, which is significant to analyze space-time link algorithm of MIMO systems.