用神经网络方法对卡巴醌系列抗肿瘤药物的QSAR研究

运用人工神经网络方法研究了卡巴醌（Ｃａｒｂｏｑｕｏｎｅ）系列药物对用Ｌ－１２０１白血病细胞接种的小鼠延长生命的活性，与传统的回归方法进行比较，可得到更为精确的结果，并且在活性预测方面有很好的效果。     

The persistent anomaly of summertime circulation over the Ural Mountains

The tropical heating and transient activity features during the period of the persistent anomaly of summertime circulation over the Ural Mountains are studied, and a possible mechanism responsible for formation and maintenance of persistent anomalies is proposed. The mechanism can be summarized as a kind of self-sustaining through a two-way interaction of stationary wave with transient eddies under the consistent forcing of abnormal heating in the tropics.     

振动过程的数值模拟实验

利用数学问题的通用软件包Mathematica，设计出一组新颖的数值模拟实验，可以有效地帮助学生通过自己探索来了解和掌握振动过程的规律，促进学生创新精神和实际能力的培养。     

浅谈《劳动合同法》对企业人力资源管理的启示

劳动合同制度是企业进行人力资源管理的基础,《劳动合同法》从保护劳动者权益的角度出发,对企业人力资源管理工作提出了严格的规定和要求。笔者就如何正确认识劳动合同法的内在作用,切实提高现实劳动用工管理水平作一简要分析。     

稻糠制取草酸研究

研究了以稻糠为原料用水解－氧化－水解法制取草酸的工艺方法。确定了最佳工艺条件，在此条件下，草酸二水合物收率可达８０％。     

遗传算法中模式空间结构的研究

通过引入模式的线性表示概念，给出了模式空间的独立性及线表示式。     

Method for tumor recognition with short dynamic PET images: theory and simulation study

A new method was provided in this paper to recognize tumor in PET images automatically and reduce the waiting time of patient. Based on the unsupervised clustering algorithm (ISODATA), this method diagnoses tumor with short dynamic PET images. The theoretical basis of this method is that the metabolic characteristics of different tissues, represented by time activity curve in the region of interest, are distinctive. The computer program was developed and validated using simulated dynamic PET data with small tumor in lung. Simulation study shows that, this method could recognize tumor with the short dynamic PET data in 10 min successfully, and this method was not sensitive to initial cluster center.     

环境类课程教学过程中的思考与改进

针对学院开设的环境类课程,探讨了如何根据不同专业、不同层次的学生进行不同深度的环境教育,以及如何改革课堂教学的形式,推进高等专科学校环境教育的发展.     

计算机在学生综合素质模糊评价中的应用

利用模糊数学的理论，对大学生的综合素质进行科学评价，同时应用 Ｖｉｓｕａｌ Ｆｏｘｐｒｏ编程技术开发系统软件实现了评价工作的自动化．     

The DNA concentration effect on DNA radiation damage induced by <Superscript>7</Superscript>Li ions and γ rays

To evaluate the influence of the DNA concentration in the aqueous solution on DNA radiation damage, the plasmid DNA in the presence or absence of Mannitol （scavenger of free radical OH.） was irradiated by ^7Li ions and γ rays at various DNA concentrations. Gel electrophoresis analysis revealed that the DNA damage of single and double strand breaks induced by irradiation became more severe at lower DNA concentration. In the condition of γ-ray irradiation, most of double strand breaks （DSB） damage was neutralized and less associated with DNA concentration in the presence of mannitol. However, under ^7Li irradiation, DSB damage could not be cleared by mannitol but was gradually aggravated with decreasing DNA concentrations. These findings imply that under low-LET irradiation, most of the DSB damage is generated by free radical OH·diffusion, and thus may be counteracted by scavengers, while at higher-LET irradiation, quite a fraction of DSB induction is caused by direct ionizing energy deposition of heavy ions, which cannot be eliminated. This work also indicates that the proportion between free radical damage and direct ionizing damage is s constant which is independent of DNA concentration when the DNA concentration is under a certain value （50ng/μL）. Our study sheds light on the un- derlying mechanisms in the DNA radiation damage process.