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21.
Imprinted microRNA genes transcribed antisense to a reciprocally imprinted retrotransposon-like gene 总被引:18,自引:0,他引:18
Seitz H Youngson N Lin SP Dalbert S Paulsen M Bachellerie JP Ferguson-Smith AC Cavaillé J 《Nature genetics》2003,34(3):261-262
MicroRNAs (miRNAs) are an abundant class of RNAs that are approximately 21-25 nucleotides (nt) long, interact with mRNAs and trigger either translation repression or RNA cleavage (RNA interference, RNAi) depending on the degree of complementarity with their targets. Here we show that the imprinted mouse distal chromosome 12 locus encodes two miRNA genes expressed from the maternally inherited chromosome and antisense to a retrotransposon-like gene (Rtl1) expressed only from the paternal allele. 相似文献
22.
Daniel S. Yeung Wing W. Y. Ng Aki P. F. Chan Patrick P. K. Chan Michael Firth Eric C. C. Tsang 《系统科学与系统工程学报(英文版)》2007,16(2):166-180
Company bankruptcies cost billions of dollars in losses to banks each year. Thus credit risk prediction is a critical part of a bank's loan approval decision process. Traditional financial models for credit risk prediction are no longer adequate for describing today's complex relationship between the financial health and potential bankruptcy of a company. In this work, a multiple classifier system (embedded in a multiple intelligent agent system) is proposed to predict the financial health of a company. In our model, each individual agent (classifier) makes a prediction on the likelihood of credit risk based on only partial information of the company. Each of the agents is an expert, but has limited knowledge (represented by features) about the company. The decisions of all agents are combined together to form a final credit risk prediction. Experiments show that our model out-performs other existing methods using the benchmarking Compustat American Corporations dataset. 相似文献
23.
The paper presents a unified, fully recursive approach to the modelling and forecasting of non-stationary time-series. The basic time-series model, which is based on the well-known ‘component’ or ‘structuraL’ form, is formulated in state-space terms. A novel spectral decomposition procedure, based on the exploitation of recursive smoothing algorithms, is then utilized to simplify the procedures of model identification and estimation. Finally, the fully recursive formulation allows for conventional or self-adaptive implementation of state-space forecasting and seasonal adjustment. Although the paper is restricted to the consideration of univariate time series, the basic approach can be extended to handle explanatory variables or full multivariable (vector) series. 相似文献
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建立一个有限缓冲区的单服务器模型,证明了在队长有有限二阶矩的条件下,输出过程具强渐近二阶自相似性质与输出过程具强渐近二阶自相似性质等价。 相似文献
27.
系统研究了多环芳烃的结构与命名及其对称性分类,对正规苯型筒环芳烃的结构与命名进行了研究,提出了一种新的分界命名法,给出了产生正规苯型稠环芳烃的两个定理,并用微机获得了它们的结构生成,系统命名,结构计数和对称性分类,另外还研究了关于正规苯型稠环芳烃和其它相关分子极性的某些问题。 相似文献
28.
See-How Ng 《复旦学报(自然科学版)》2007,(5)
1 Results In order to develop high capacity anode materials for enhancing the performance of lithium-ion batteries,silicon (Si) and a variety of metals that alloy with lithium,such as Sn,Sb,and Al,were studied and found to be promising candidates as anode materials[1-4].Among them,Si appears to be the most attractive candidate due to its large theoretical lithium insertion capacity of 4 200 mAh g-1[1].Unfortunately,there is one severe problem with the application of Si anode,i.e., the large volume chang... 相似文献
29.
Zusammenfassung Für das Aconitum-Alkaloid Napellin wurden auf Grund einer eingehenden Diskussion des Tatsachenmaterials die Strukturen XI bzw. X vorgeschlagen. Das Alkaloid Songorin ist das dazugehörige Ring-D-Keton. 相似文献
30.
Marchis F Hestroffer D Descamps P Berthier J Bouchez AH Campbell RD Chin JC van Dam MA Hartman SK Johansson EM Lafon RE Le Mignant D de Pater I Stomski PJ Summers DM Vachier F Wizinovich PL Wong MH 《Nature》2006,439(7076):565-567
The Trojan population consists of two swarms of asteroids following the same orbit as Jupiter and located at the L4 and L5 stable Lagrange points of the Jupiter-Sun system (leading and following Jupiter by 60 degrees ). The asteroid 617 Patroclus is the only known binary Trojan. The orbit of this double system was hitherto unknown. Here we report that the components, separated by 680 km, move around the system's centre of mass, describing a roughly circular orbit. Using this orbital information, combined with thermal measurements to estimate the size of the components, we derive a very low density of 0.8(- 0.1)+0.2 g cm(-3). The components of 617 Patroclus are therefore very porous or composed mostly of water ice, suggesting that they could have been formed in the outer part of the Solar System. 相似文献