Cellular control of the tick-borne virus antigen production in persistently infected cell culture

Summary The influence of inhibition or stimulation of cellular DNA synthesis on tick-borne virus antigen production in persistently infected cell culture was studied. Either mitomycin C or cytosine-arabinoside caused cessation of antigen-containing cell number increase. Stimulation of cellular DNA synthesis by growth medium change increased the level of antigen-containing cells. When HEp-2-Sof culture was synchronized, a correlation was observed between the entrance of cells into DNA synthesis phase and the increase of proportion of antigen-containing cells.     

Action of insulin on the glycogen content of liver and muscle of the murrel,Ophicephalus striatus (Bloch)

Résumé Des doses variées d'insuline administrées à l'Ophicephalus striatus ont augmenté la quantité de glycogène du foie et des muscles. Dans le foie, les doses étant fortes (40 IU et 60 IU), la quantité normale de glycogène a presque quadruplé et elle a plus que septuplé dans les muscles. Le mécanisme possible présidant à l'action de l'insuline est aussi discuté.     

On the occurrence of homovanillic acid and 3-methoxy-4-hydroxymandelic acid in human cerebrospinal fluid

Zusammenfassung Es wird papierchromatographisch gezeigt, dass Cerebrospinalflüssigkeit gesunder Menschen sowohl Homovanillinsäure als auch 3-Methoxy-4-hydroxymandelsäure enthält. Die Konzentration der ersteren ist etwa 75 ng/ml und die der letzteren etwa 25 ng/ml.

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Acknowledgment. This work has been supported by grants from Leo Ltd., Hälsingborg, and from the Medical Faculty, University of Göteborg (Sweden). For technical assistance we are indebted to Mrs.I. Olofson.