Compte rendu des publications

Cellular and Molecular Life Sciences -     

Über die Verwendung von künstlichen radioaktiven Isotopen zur Erzielung von lokalisierten biologischen Strahlenwirkungen

Summary The author made a first attempt to utilize an artificial radioactive isotope for the production of localized biological radiation-effects, by means of intraperitoneal injections of radiozinc (Zn⁶³) suspended in a solution of pectine. Experiments were performed on mice and rabbits and the procedure was applied, for the purpose of preliminary therapeutic investigations, to a case of carcinoma of the ovary with severe peritoneal extension.     

Über die Einwirkung von Chlordioxyd auf Pektinstoffe

Ohne Zusammenfassung     

Der Vitaminbedarf des amerikanischen ReismehlkäfersTribolium confusum Duval

Summary As previously reported the larvae ofTribolium confusum require two unknown factors obtainable from yeast apart from various vitamines of the B-group for normal growth. One of these possesses acidic properties. This factor could be fully replaced by a folic acid preparation of potency 4000 kindly placed at our disposal by Prof.R. J. Williams. This may be regarded as a possibility but not as a proof that folic acid is the reported factor.

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C. A. Grob dankt der Haco-Gesellschaft AG., Gümligen, für die Unterstützung dieser Arbeit.     

Zur Chemotherapie der Tuberkulose

Summary The paper deals with recent advances in chemotherapy of tuberculosis. In view of the fact that chemical analysis has shown the lipoid nature of tubercle bacilli and in view of the favorable therapeutic results obtained by treating leprosy with chaulmoogra-acids, the leading idea of many authors was to synthetize lipoidsoluble substances in order to affect the growth of tubercle bacilli. However, the finding that water-soluble substances as Promin inhibit the growth of the microorganisms showed that the idea to use exclusively fatsoluble substances was not necessarily right. Although the therapeutic effects of Promin are not yet particularly encouraging, the experiments made with this substances are useful as they indicate a new direction for research in chemotherapy of tuberculosis. Some of our own experiments with diaminodiphenylsulphone-derivatives are described.     

Nachweis eines androgenen Wirkstoffes im Hypophysenvorderlappen

Ohne Zusammenfassung9. Mitt. Untersuchungen über Organextrakte; 8. Mitt. vgl. Helv. chim. acta28 im Druck.     

Zur Entstehung des Lungenödems

Ohne Zusammenfassung     

Der Einfluß der Nebenniere auf die Kreislaufwirkung des Adrenalins

Summary Traces of nor-adrenaline restore the vascular action of adrenaline altered in epinephrectomized dogs to the reaction of the normal animal. Therefore it is claimed that the adrenals discharge one or several substances into the blood stream, which are necessary for the usual peripheral vascular action of adrenaline. Further investigations are in progress.