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941.
ZHAO DongMin ZHAO JiQuant ZHAO ShanShan HE LeQin WANG WeiYu 《科学通报(英文版)》2007,52(17):2337-2344
A secondary amino-modified mesoporous molecular sieve MCM-41 was obtained by reaction of bis(3-(triethoxysilyl)propyl)amine with MCM-41. The chiral Salen-Mn (III) complex was anchored onto the modified MCM-41 by a multi-step grafting method and two heterogenized catalysts with different Mn contents were obtained. The catalysts were characterized by XRD, N2 adsorption, ICP, FT-IR and DR UV-Vis. Their catalysis on asymmetric epoxidation of several olefins was studied with NaClO and m-CPBA as oxidants respectively. It was found that both the activity and enantioselectivity of the cata- lysts decreased after the homogeneous catalyst was heterogenized. The reasons resulting in the de- crease of catalytic performance were discussed. 相似文献
942.
Mechanism of the interaction between Au nanoparticles and polymerase in nanoparticle PCR 总被引:1,自引:0,他引:1
MI LiJuan ZHU HongPing ZHANG XiaoDong HU Jun FAN ChunHai 《科学通报(英文版)》2007,52(17):2345-2349
Nanoparticle PCR is a novel method to optimize DNA amplification. It performs well in improving specificity, enhancing sensitivity and speed. Several mechanisms were proposed in previous studies: one was based on the interaction between gold nanoparticles (AuNPs) and DNA while the other was attributed to the heat transfer property of AuNPs. In this paper, we propose that the interaction between AuNPs and DNA polymerase can significantly influence PCR. First, the addition of DNA polymerase can eliminate the inhibitory effects of excess AuNPs. Second, the addition of AuNPs will increase yield of the desired PCR product and make the optimum concentration of DNA polymerase move to higher value. Third, while excess polymerase might inhibit amplification efficiency, AuNPs can reverse this process and the yield of PCR amplification. Based on these results we propose a possible mechanism that AuNPs might modulate the activity of polymerase and improve PCR amplification. 相似文献
943.
在体外使用CD40L作用于B淋巴细胞使之活化,通过测定B淋巴细胞表面分子及分泌细胞因子的变化,探讨B淋巴细胞作为抗原递呈细胞在抗肿瘤免疫中的优势,为B淋巴细胞特异性活化细胞毒T淋巴细胞(cytotoxic T lymphocyte,CTL)进而发挥其肿瘤细胞杀伤效应奠定基础.取7名健康成人外周静脉血,经淋巴细胞分离液分离人外周血单个核细胞(PBMC),分为对照组和实验组,实验组培养液中加入加入CD40L和IL-4,共培养21 d.观察B淋巴细胞生长状况,并在第7 d、第14 d和第21 d,用流式细胞仪(FCAS)测定其表面分子CD80、CD86和CD19,在第21 d,使用酶联免疫吸附法(ELISA)测定培养液中的IL-12水平.结果显示,在CD40L的作用下,B淋巴细胞呈克隆样增殖,并高表达表面分子CD80/CD86和CD19,和对照组相比,B淋巴细胞分泌IL-12水平升高(P<0.05).上述实验结果说明通过CD40L的刺激,B淋巴细胞得到了活化,提示通过该途径活化的B淋巴细胞具备了作为抗原递呈细胞而发挥其抗肿瘤免疫治疗的能力. 相似文献
944.
Now vibration isolation of ultra-precision machine tool is usually achieved through air-springs systems. As far as HCM-I sub-micro turning machine developed by HIT, an active vibration isolation system that consists of air-springs and electro-magnetic actuators was presented. The primary function of air-springs is to support the turning machine and to isolate the high-frequency vibration. The electro-magnetic actuators controlled by fuzzy-neural networks isolate the low-frequency vibration. The experiment indicates that active vibration isolation system isolates base-vibration effectively in all the frequency range. So the vibration of the machine bed is controlled under 10-6g and the surface roughness is improved. 相似文献
945.
Kai Xu 《系统科学与复杂性》2017,30(5):1173-1188
This paper is concerned with the problem of improving the estimator of covariance matrix under Stein’s loss. By the partial Iwasawa coordinates of covariance matrix, the corresponding risk can be split into three parts. One can use the information in the weighted matrix of weighted quadratic loss to improve one part of risk. However, this paper indirectly takes advantage of the information in the sample mean and reuses Iwasawa coordinates to improve the rest of risk. It is worth mentioning that the process above can be repeated. Finally, a Monte Carlo simulation study is carried out to verify the theoretical results. 相似文献
946.
This paper considers the nonstandard renewal risk model in which a part of surplus is invested into a Black-Scholes market whose price process is modelled by a geometric Brownian motion, claim sizes form a sequence of not necessarily identically distributed and pairwise quasi-asymptotically independent random variables with dominatedly-varying tails.The authors obtain a weakly asymptotic formula for the finite-time and infinite-time ruin probabilities.In particular,if the claims are identically distributed and consistently-varying tailed,then an asymptotic formula is presented. 相似文献
947.
A new generation of cement, microbe cement, has been developed in response to the ever increasing awareness of environmental protection. Microbe cement is a new strengthening material based on microbiologically induced precipitation of calcium carbonate. This paper confirms the feasibility of binding loose sand particles using microbe cement and details the cementation mechanism of microbe cement. We have also prepared microbe cementitious materials (biosandstones). The compressive strength of the bio-sandstone, which depends on the content of calcium carbonate produced by microbially induced precipitation and the bio-mediated calcite crystal size, could be up to 12 MPa at an age of 20 days. By increasing the precipitated calcite content, the compressive strength and microstructure of bio-sandstone could be improved. 相似文献
948.
K-means clustering is arguably the most popular technique for partitioning data. Unfortunately, K-means suffers from the well-known
problem of locally optimal solutions. Furthermore, the final partition is dependent upon the initial configuration, making
the choice of starting partitions all the more important. This paper evaluates 12 procedures proposed in the literature and
provides recommendations for best practices. 相似文献
949.
在多Agent系统中经常相互协作的Agent会结成具有相对稳定的合作领域和共同的交易理念,从而形成一定的公共知识,可以协作完成子任务,而多Agent协商系统中的成员既有合作性又有自利性,只有将二者有机结合起来才能保证高效地完成任务。文章在分析拍卖方式网络化、自动化、竞争化的基础上,从拍卖请求方和能力竞争方的角度,引入拍卖过程中的超时思想和Agent合作的历史信息对拍卖任务得不到及时的处理和由于拍卖方和竞买方的信息不对称,没有考虑历史信息的情况下成交效率太低进行分析、研究,提出一种多Agent拍卖流程框架和协商算法,从而使得在拍卖中各响应者都以积极并诚实的姿态参与协商,以致大大地提高了协商效率,且增加了响应者之间的透明性。 相似文献
950.
This paper presents a fast pseudorandom generation algorithm, which is based on the BLAKE hash function and can pass the random
test of the NIST (National Institute of Standards and Technology) Statistical Test Suite. Through theoretical analysis and
experimental imitation, our new algorithm is proven to be more secure and efficient than G-SHA1. Simultaneously, we introduce
and discuss the BLAKE in detail. Its security shows that can be utilized to generate pseudorandom bit sequences, which the
experimental results show the BLAKE hash function has excellent pseudorandomness. Therefore, we believe the BLAKE is one of
the most potential candidate algorithms of SHA-3 program. 相似文献