基于多属性决策的供应链排序问题研究

文章以生产排序费用和分批发送费用总和最小为排序目标,考虑包含单个供应商向多制造商供应工件的供应链排序问题,并建立了问题的数学模型;提出了一种融合多属性决策方法的动态规划算法,给出了相应算例,并分析了算法的复杂度。     

一种带验证和撤销的组密钥分发方案

提出一种在无线传感器网络中具有正确性验证和头结点撤销功能的组密钥更新方案. 通过建立组密钥之间的冗余关联,实现了在不增加结点负担的情况下,合法结点利用当前广播消息和自身秘密恢复丢失的组密钥. 利用撤销多项式实现对结点和头结点的撤销,此外还能提供密钥的正确性验证. 分析表明,在没有增加计算开销和通信开销情况下本方案具有更好的安全性.     

基于智能酒精检测的汽车启动控制系统设计

针对近年来频繁发生的酒后驾车事故,设计一款车载酒精止动装置,以12C5A08S2单片机为主要芯片,蜂鸣器和LED灯为报警装置,应用小波分析确定浓度与电压关系函数,当酒精探头检测浓度超过设定阈值时,汽车点火回路立即被继电器切断．     

大功率LED阵列散热结构热分析

在自然对流冷却状态下,不同的散热结构对大功率LED阵列散热性能有显著影响。采用有限元分析法,对不同散热模型进行了分析并得到工作稳定时的热分析图;对比直片形、弧形、弧钉形散热结构的散热效果,逐步得出弧钉形散热结构散热效果最好,使得空腔以及芯片处温度均在合适的范围内,灯具的使用寿命达到近40000h。另外,模拟得出在普通散热设计中,灯具适合的功率约为13．75w。通过有限元法仿真模拟得出较为合理的结果,有效地减少了实验损耗。     

清代合肥的城垣建设

清代的合肥是庐州府治所所在,清代的合肥城垣包含了诸多的历史信息,研究清代的城垣修建,对我们了解清代合肥的经济、政治、军事的影响有着重要的作用。     

Pharmaco-metabonomic phenotyping and personalized drug treatment

There is a clear case for drug treatments to be selected according to the characteristics of an individual patient, in order to improve efficacy and reduce the number and severity of adverse drug reactions. However, such personalization of drug treatments requires the ability to predict how different individuals will respond to a particular drug/dose combination. After initial optimism, there is increasing recognition of the limitations of the pharmacogenomic approach, which does not take account of important environmental influences on drug absorption, distribution, metabolism and excretion. For instance, a major factor underlying inter-individual variation in drug effects is variation in metabolic phenotype, which is influenced not only by genotype but also by environmental factors such as nutritional status, the gut microbiota, age, disease and the co- or pre-administration of other drugs. Thus, although genetic variation is clearly important, it seems unlikely that personalized drug therapy will be enabled for a wide range of major diseases using genomic knowledge alone. Here we describe an alternative and conceptually new 'pharmaco-metabonomic' approach to personalizing drug treatment, which uses a combination of pre-dose metabolite profiling and chemometrics to model and predict the responses of individual subjects. We provide proof-of-principle for this new approach, which is sensitive to both genetic and environmental influences, with a study of paracetamol (acetaminophen) administered to rats. We show pre-dose prediction of an aspect of the urinary drug metabolite profile and an association between pre-dose urinary composition and the extent of liver damage sustained after paracetamol administration.     

Positive and negative effects of widespread badger culling on tuberculosis in cattle

Human and livestock diseases can be difficult to control where infection persists in wildlife populations. For three decades, European badgers (Meles meles) have been culled by the British government in a series of attempts to limit the spread of Mycobacterium bovis, the causative agent of bovine tuberculosis (TB), to cattle. Despite these efforts, the incidence of TB in cattle has risen consistently, re-emerging as a primary concern for Britain's cattle industry. Recently, badger culling has attracted controversy because experimental studies have reached contrasting conclusions (albeit using different protocols), with culled areas showing either markedly reduced or increased incidence of TB in cattle. This has confused attempts to develop a science-based management policy. Here we use data from a large-scale, randomized field experiment to help resolve these apparent differences. We show that, as carried out in this experiment, culling reduces cattle TB incidence in the areas that are culled, but increases incidence in adjoining areas. These findings are biologically consistent with previous studies but will present challenges for policy development.     

A low density of 0.8 g cm(-3) for the Trojan binary asteroid 617 Patroclus

The Trojan population consists of two swarms of asteroids following the same orbit as Jupiter and located at the L4 and L5 stable Lagrange points of the Jupiter-Sun system (leading and following Jupiter by 60 degrees ). The asteroid 617 Patroclus is the only known binary Trojan. The orbit of this double system was hitherto unknown. Here we report that the components, separated by 680 km, move around the system's centre of mass, describing a roughly circular orbit. Using this orbital information, combined with thermal measurements to estimate the size of the components, we derive a very low density of 0.8(- 0.1)+0.2 g cm(-3). The components of 617 Patroclus are therefore very porous or composed mostly of water ice, suggesting that they could have been formed in the outer part of the Solar System.     

液晶模块在动态图像显示中的应用

利用液晶显示模块代替系统机实现波形和数据的动态显示,并对波形进行"防抖动"处理.运用同步技术对采样数据进行归一化处理,将处理后数据转化为相对应的坐标,并运用直线插值法求出间隔点之间坐标;将所有坐标转化为存储单元地址,点亮存储单元地址上的点进行图形绘制;并将绘制的图形等间隔时间移动.绘制的图形连贯,动态特性良好,无抖动现象,静态参数和动态图像可以共存.通过实做的课题证明该方法算法简单,方便快捷,应用于实际工程中可以大大降低成本.