高校法制教育与心理教育整合研究

研究高校法制教育与心理教育的整合,主要目的是将两种教育融会贯通,真正达到教育大学生,指引他们形成正确的价值观、人生观以及世界观的目标。可从教材整合、授课内容丰富、专业师资力量培养、利用现代教学设备方面来整合心理教育与法律教育。     

The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease

The recycling of the amyloid precursor protein (APP) from the cell surface via the endocytic pathways plays a key role in the generation of amyloid beta peptide (Abeta) in Alzheimer disease. We report here that inherited variants in the SORL1 neuronal sorting receptor are associated with late-onset Alzheimer disease. These variants, which occur in at least two different clusters of intronic sequences within the SORL1 gene (also known as LR11 or SORLA) may regulate tissue-specific expression of SORL1. We also show that SORL1 directs trafficking of APP into recycling pathways and that when SORL1 is underexpressed, APP is sorted into Abeta-generating compartments. These data suggest that inherited or acquired changes in SORL1 expression or function are mechanistically involved in causing Alzheimer disease.     

Nodal signals pattern vertebrate embryos

Vertebrate embryonic patterning requires several conserved inductive signals–including Nodal, Bmp, Wnt and Fgf signals. Nodal, which is a member of the transforming growth factor β (TGFβ) superfamily, activates a signal transduction pathway that is similar to that of other TGFβ members. Nodal genes, which have been identified in numerous vertebrate species, are expressed in specific cell types and tissues during embryonic development. Nodal signal transduction has been shown to play a pivotal role in inducing and patterning mesoderm and endoderm, and in regulating neurogenesis and left-right axis asymmetry. Antagonists, which act at different steps in the Nodal signal transduction pathway, have been shown to tightly modulate the inductive activity of Nodal. Received 20 October 2005; received after revision 15 November 2005; accepted 25 November 2005     

不良气象微环境下桥塔横梁覆冰灾害过程模拟

冬季桥塔横梁坠冰是威胁桥梁交通安全的重大隐患之一,系统分析不良气象微环境下横梁覆冰灾害过程机制,是保证桥梁交通安全的迫切需求。本文依托FLUENT与FENSAP-ICE软件建立了桥塔横梁覆冰数值仿真模型,探讨了风速、液态水含量和环境温度等微气象参数对桥塔横梁覆冰灾害演化过程的影响规律。结果表明：本文提出的数值仿真方法在明冰及霜冰条件下均具有较高的可行性与准确性;对武汉长江二桥桥塔横梁结冰数值模拟发现,覆冰区域集中分布于横梁迎风侧前缘及上下边缘,整体呈现出“U”型分布特征,是横梁防冰、除冰的重点区域;不良气象微环境是影响横梁结冰形态、分布及覆冰量的重要因素,覆冰形状受风速、液态含水量影响较大,受温度影响较小。     

基于复杂网络的多机场航班延误传播分析

为了研究多机场间航班延误的传播机理,将机场作为节点,航线作为边构成复杂网络。通过分析传染病传播过程与机场间航班延误传播过程的相似性,借鉴经典传染病传播模型(SIR)的思想,并考虑不同机场间延误传播的差异,提出机场重要度的概念,构建了多机场航班延误传播模型。对多机场航班延误传播过程的仿真结果表明:在多机场网络中,初始延误机场不同以及机场重要度不同,延误传播效果不同,但延误传播规律保持不变。对网络中重要机场进行相应管控会使发生延误的机场数量峰值下降,且按照介数值确定需进行管控的重要机场,网络中发生延误机场数量峰值下降率最大。可见,该模型可以客观反映多机场间航班延误传播的动态过程和变化规律,并可为延误的预防和恢复提供理论依据。     

7种化学杀菌剂和拮抗菌代谢物对苹果斑点落叶病菌的抑制活性及增效组合筛选

目的 为苹果斑点落叶病的防控提供新颖的杀菌剂及其增效组合。方法 采用菌丝生长速率法测定了7种化学杀菌剂、拮抗菌发酵代谢物及其复配剂对苹果斑点落叶病菌的抑制活性。结果 7种化学杀菌剂均对病菌有较强的抑制活性,其中戊唑醇、苯醚甲环唑和丙环唑3种药剂对病菌抑制效果最佳,EC₅₀分别达0.21、0.30和0.81 μg/mL,其次为吡唑醚菌酯、代森锰锌和嘧菌酯。多菌灵的抑菌效果最差,EC₅₀为15.03 μg/mL。生防菌发酵上清液和发酵上清粗提物对病菌的EC₅₀分别为2.38 μL/mL和0.53 μL/mL。发酵上清液粗提物和代森锰锌、吡唑醚菌酯的复配均表现为增效作用,其中体积比6∶4和7∶3达最大毒性比,分别为1.39和1.41。结论 戊唑醇、苯醚甲环唑和丙环唑对苹果斑点落叶病菌的毒力最大。解淀粉芽孢杆菌SJ1606所产粗提物对化学杀菌剂代森锰锌和吡唑醚菌酯具有增效作用,为后续农药新制剂研发提供了参考数据。     

Interaction model of artificial fish in virtual environment

Conventional artificial fish has some shortages on the interaction with environment, other fish, and the animator. This article proposes a multi-tier interaction control model of artificial fish, realizes the interaction model through integration of virtual reality technology and Markov sequence, and provides a virtual marine world to describe the interaction between artificial fish and the virtual environment and the interaction between the artificial fish and the animator. Simulation results show that the interaction model owns not only the basic characteristics of virtual biology, but also has high trueness interaction function.     

A STAGE-STRUCTURED SI ECO-EPIDEMIOLOGICAL MODEL WITH TIME DELAY AND IMPULSIVE CONTROLLING*

This paper formulates a robust stage-structured SI eco-epidemiological model with periodic constant pulse releasing of infectious pests with pathogens. The authors show that the conditions for global attractivity of the ＇pest-eradication＇ periodic solution and permanence of the system depend on time delay, hence, the authors call it ＂profitless＂. Further, the authors present a pest management strategy in which the pest population is kept under the economic threshold level （ETL） when the pest population is uniformly persistent. By numerical analysis, the authors also show that constant maturation time delay for the susceptible pests and pulse releasing of the infectious pests can bring obvious effects on the dynamics of system.     

基于SVD的通信信号背景下脉冲波形和初相估计

雷达侦察接收机往往侦察到的是通信和雷达脉冲的混合信号,如何从通信信号背景中有效提取出雷达脉冲波形,是现代雷达信号处理领域中的重要内容。针对这一问题,提出了一种基于奇异值分解的通信与雷达混合信号中脉冲波形估计算法。该算法通过对信号观测矩阵的奇异值分析和协方差矩阵的特征值分析,证明了观测矩阵的奇异值分解具有稳定性,并且奇异值分解能够最佳近似观测信号的线性特征,给出了一种利用左右奇异向量估计脉冲波形及其相对初相的方法。本文的算法适用于任意脉冲波形,并且能够在较低信噪比环境下估计脉冲信号波形和相对相位,仿真结果证明了算法的有效性。     

Design and realization of threshold secret sharing scheme with random weights

A new threshold secret sharing scheme is constructed by introducing the concept of share vector, in which the number of shareholders can be adjusted by randomly changing the weights of them. This kind of scheme overcomes the limitation of the static weighted secret sharing schemes that cannot change the weights in the process of carrying out and the deficiency of low efficiency of the ordinary dynamic weighted sharing schemes for its resending process. Thus, this scheme is more suitable to the case that the number of shareholders needs to be changed randomly during the scheme is carrying out.