全文获取类型
收费全文 | 966篇 |
免费 | 3篇 |
国内免费 | 3篇 |
专业分类
系统科学 | 7篇 |
丛书文集 | 1篇 |
教育与普及 | 3篇 |
理论与方法论 | 14篇 |
现状及发展 | 83篇 |
研究方法 | 183篇 |
综合类 | 618篇 |
自然研究 | 63篇 |
出版年
2020年 | 4篇 |
2018年 | 6篇 |
2017年 | 13篇 |
2016年 | 7篇 |
2015年 | 5篇 |
2014年 | 7篇 |
2013年 | 9篇 |
2012年 | 84篇 |
2011年 | 156篇 |
2010年 | 23篇 |
2009年 | 9篇 |
2008年 | 76篇 |
2007年 | 82篇 |
2006年 | 91篇 |
2005年 | 86篇 |
2004年 | 67篇 |
2003年 | 75篇 |
2002年 | 89篇 |
2001年 | 2篇 |
2000年 | 19篇 |
1999年 | 4篇 |
1997年 | 3篇 |
1996年 | 2篇 |
1994年 | 3篇 |
1993年 | 1篇 |
1992年 | 3篇 |
1991年 | 2篇 |
1990年 | 2篇 |
1989年 | 1篇 |
1988年 | 4篇 |
1987年 | 2篇 |
1986年 | 1篇 |
1985年 | 2篇 |
1983年 | 2篇 |
1982年 | 1篇 |
1981年 | 1篇 |
1979年 | 2篇 |
1978年 | 2篇 |
1977年 | 1篇 |
1976年 | 5篇 |
1975年 | 1篇 |
1974年 | 2篇 |
1973年 | 2篇 |
1972年 | 1篇 |
1971年 | 3篇 |
1970年 | 5篇 |
1967年 | 2篇 |
1966年 | 1篇 |
1965年 | 1篇 |
排序方式: 共有972条查询结果,搜索用时 156 毫秒
131.
H Lesot K von der Mark J V Ruch 《Comptes rendus des séances de l'Académie des sciences. Série D, Sciences naturelles》1978,286(10):765-768
The different types of collagen synthesized by embryonic Mouse tooth germs were analysed using an immunohistiological method. The tooth germs were shown to synthesize at least three genetically distinct collagen types: I, III and IV. 相似文献
132.
133.
Summary The effects of the novel and selective dopamine D-1 agonist CY 208-243 on the rat hypothalamo-hypophyseal-gonadal (HHG) axis were studied. CY 208-243 did not modify the concentration of luteinizing hormone (LH) in serum from female or male rats, and had no effect upon opiate antagonist-induced stimulation of LH secretion in male rats. CY 208-243 did not inhibit ovulation in cycling female rats. Thus, D-1 receptor activation by systemic drug administration does not alter HHG function in rats. 相似文献
134.
135.
Effect of lithium on brain dopamine 总被引:3,自引:0,他引:3
136.
137.
Monsuur AJ de Bakker PI Alizadeh BZ Zhernakova A Bevova MR Strengman E Franke L van't Slot R van Belzen MJ Lavrijsen IC Diosdado B Daly MJ Mulder CJ Mearin ML Meijer JW Meijer GA van Oort E Wapenaar MC Koeleman BP Wijmenga C 《Nature genetics》2005,37(12):1341-1344
Celiac disease is probably the best-understood immune-related disorder. The disease presents in the small intestine and results from the interplay between multiple genes and gluten, the triggering environmental factor. Although HLA class II genes explain 40% of the heritable risk, non-HLA genes accounting for most of the familial clustering have not yet been identified. Here we report significant and replicable association (P = 2.1 x 10(-6)) to a common variant located in intron 28 of the gene myosin IXB (MYO9B), which encodes an unconventional myosin molecule that has a role in actin remodeling of epithelial enterocytes. Individuals homozygous with respect to the at-risk allele have a 2.3-times higher risk of celiac disease (P = 1.55 x 10(-5)). This result is suggestive of a primary impairment of the intestinal barrier in the etiology of celiac disease, which may explain why immunogenic gluten peptides are able to pass through the epithelial barrier. 相似文献
138.
139.
Smirnakis SM Brewer AA Schmid MC Tolias AS Schüz A Augath M Inhoffen W Wandell BA Logothetis NK 《Nature》2005,435(7040):300-307
Several aspects of cortical organization are thought to remain plastic into adulthood, allowing cortical sensorimotor maps to be modified continuously by experience. This dynamic nature of cortical circuitry is important for learning, as well as for repair after injury to the nervous system. Electrophysiology studies suggest that adult macaque primary visual cortex (V1) undergoes large-scale reorganization within a few months after retinal lesioning, but this issue has not been conclusively settled. Here we applied the technique of functional magnetic resonance imaging (fMRI) to detect changes in the cortical topography of macaque area V1 after binocular retinal lesions. fMRI allows non-invasive, in vivo, long-term monitoring of cortical activity with a wide field of view, sampling signals from multiple neurons per unit cortical area. We show that, in contrast with previous studies, adult macaque V1 does not approach normal responsivity during 7.5 months of follow-up after retinal lesions, and its topography does not change. Electrophysiology experiments corroborated the fMRI results. This indicates that adult macaque V1 has limited potential for reorganization in the months following retinal injury. 相似文献
140.