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Lilian Mariana Costa Guilherme Henrique Silva de Freitas Marcos Rodrigues 《Journal of Natural History》2019,53(7-8):391-412
Cipo Canastero (Asthenes luizae) is a bird endemic to Brazilian mountaintops, inhabiting rock outcrop habitats of the campos rupestres in the southern Espinhaço Range. Available data about Cipo Canastero’s breeding biology are scarce, incomplete or inconsistent. All nests found to date were built in the plant Vellozia nivea. Based on 84 nests found from 2009 to 2017 in four sites at Serra do Cipó, we described in detail their nesting habits focusing on three groups of characters: nest architecture, composition, and placement. Also, we described nest building. Our major new findings on the nesting habits of A. luizae were: three nest layers distinguishable, inner lining covering the entire nest interior, tunnels and tubes are absent, and the nest sites are not restricted to V. nivea. We recorded a wide range of nest sites, from ground, grasses and rupicolous bromeliads to shrubs and trees, including at least 30 supporting-plant species. Nest supports varied among study sites. Nest building lasted 22 days (one nest) and was done by both members of the pair. Our data can be useful for species conservation and contribute to the knowledge of the natural history of the genus Asthenes. 相似文献
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A human IFNGR1 small deletion hotspot associated with dominant susceptibility to mycobacterial infection 总被引:25,自引:0,他引:25
Jouanguy E Lamhamedi-Cherradi S Lammas D Dorman SE Fondanèche MC Dupuis S Döffinger R Altare F Girdlestone J Emile JF Ducoulombier H Edgar D Clarke J Oxelius VA Brai M Novelli V Heyne K Fischer A Holland SM Kumararatne DS Schreiber RD Casanova JL 《Nature genetics》1999,21(4):370-378
The immunogenetic basis of severe infections caused by bacille Calmette-Guérin vaccine and environmental mycobacteria in humans remains largely unknown. We describe 18 patients from several generations of 12 unrelated families who were heterozygous for 1 to 5 overlapping IFNGR1 frameshift small deletions and a wild-type IFNGR1 allele. There were 12 independent mutation events at a single mutation site, defining a small deletion hotspot. Neighbouring sequence analysis favours a small deletion model of slipped mispairing events during replication. The mutant alleles encode cell-surface IFNgamma receptors that lack the intra-cytoplasmic domain, which, through a combination of impaired recycling, abrogated signalling and normal binding to IFNgamma exert a dominant-negative effect. We thus report a hotspot for human IFNGR1 small deletions that confer dominant susceptibility to infections caused by poorly virulent mycobacteria. 相似文献