Fibulin-5/DANCE is essential for elastogenesis in vivo.

The elastic fibre system has a principal role in the structure and function of various types of organs that require elasticity, such as large arteries, lung and skin. Although elastic fibres are known to be composed of microfibril proteins (for example, fibrillins and latent transforming growth factor (TGF)-beta-binding proteins) and polymerized elastin, the mechanism of their assembly and development is not well understood. Here we report that fibulin-5 (also known as DANCE), a recently discovered integrin ligand, is an essential determinant of elastic fibre organization. fibulin-5-/- mice generated by gene targeting exhibit a severely disorganized elastic fibre system throughout the body. fibulin-5-/- mice survive to adulthood, but have a tortuous aorta with loss of compliance, severe emphysema, and loose skin (cutis laxa). These tissues contain fragmented elastin without an increase of elastase activity, indicating defective development of elastic fibres. Fibulin-5 interacts directly with elastic fibres in vitro, and serves as a ligand for cell surface integrins alphavbeta3, alphavbeta5 and alpha9beta1 through its amino-terminal domain. Thus, fibulin-5 may provide anchorage of elastic fibres to cells, thereby acting to stabilize and organize elastic fibres in the skin, lung and vasculature.     

ICP方法匹配深度图像的实现

针对ICP(迭代最近点 )方法中寻找深度像之间点对应关系这一难点问题 ,首先介绍对ICP方法匹配深度图像的原理并给出单位四元数和旋转角度间的关系 ,然后提出一种验证两个深度图像中对应点对有效性的方法 ,给出了判断待匹配深度图像之间的点对应条件的准则 ,同时给出了实现这种准则的数据结构以及程序设计思想 .最后 ,用真实深度图像证明此方法的有效性 ,并用“主次缝合线”法合成匹配后的深度图像     

Post-treatments of Super Absorbent Polymer

ＩｎｔｒｏｄｕｃｔｉｏｎＩｎｏｕｒｄａｉｌｙｌｉｆｅ ,ｃｏｔｔｏｎ ,ｐａｐｅｒａｎｄｓｐｏｎｇｅａｒｅｃｏｍｍｏｎｌｙｕｓｅｄｔｏａｂｓｏｒｂｗａｔｅｒ.Ｔｈｅｓｅｍａｔｅｒｉａｌｓａｂｓｏｒｂｏｎｌｙａｆｅｗｔｉｍｅｓｔｈｅｉｒｗｅｉｇｈｔｏｆｗａｔｅｒａｎｄｈａｖｅｒａｔｈｅｒｐｏｏｒｐｒｏｐｅｒｔｉｅｓｗｉｔｈｒｅｓｐｅｃｔｔｏｗａｔｅｒｒｅｔｅｎｔｉｏｎ .Ｈｏｗｅｖｅｒ,ｓｏｍｅｔｙｐｅｓｏｆｐｏｌｙｍｅｒｓａｎｄｃｏｐｏｌｙ ｍｅｒｓｄｏｆｕｎｃｔｉｏｎａｓｈｉｇｈｗａｔｅｒａｂｓｏｒｂ…     

Ontology-Based Semantic Annotation for Problem Set Archives in the Web

0 IntroductionAsneim mapnotircta nWte pbre i-sco tnhdieti oabnilfiotry r etaoli zainnngotthatee go aWle obf trhe-esources with semanticinformation[1]. However ,annotationtools so far basically allowthe user to annotate with plaintext using the method of information extraction.In manycases ,one can hardly extract semantics from Web docu-ments ,such as problemset archivesinthe Web.Massive problemset archives are availableinthe Web,for example,http://acm.uva.es, while each problemsetarchives pr…     

英汉交际语差异及其原因初探

文章就日常生活中一些较为典型的交际情景，对英汉交际语的差异及其潜在原因作了探讨。     

中国入世对政府的影响及政府应对问题

中国成功入世后，各行各业和各市场主体都面临新的机遇和挑战，以及自我适应和应对的问题。相对而言，政府受到的影响是首要的、最为全面而深远的，政府率先入世既十分必要又相当紧迫。政府要实现真正意义上的入世，关键是要转变公务员队伍观念，提高公务员队伍的整体综合素质，转变政府职能，转变行政方式，实现依法行政。     

两段绞接式联合收割机输送槽的设计研究

本文介绍一种适宜配置在悬挂式联合收割机上的两段铰接式输送槽设计,这种输送槽后段固定,前段与割台连接并与后输送槽铰接,该铰接点为前悬挂割台的支点,借助液压油缸升降,文中对该铰接点位置的确定,以及两段输送槽铰接处的圆弧过渡板设计进行了分析研究,提供了设计方法.     

植物药超氧物歧化酶活性与某些性质的研究

应用NBT光还原法对23种植物药材SOD粗提液活性研究表明。供试材料全部达到200units·g~(-1)F·W的水平,13种超过300units·g~(-1)F·W,野山楂高达812.5units。酶的比活,玄参、何首乌位列前茅,超过300units·mg~(-1)protein~-,野山楂、枸杞等都在150units·mg~(-1)protein~(-1)以上。综合分析,何首乌、野山楂、玄参与枸杞等酶活性与比活都高,有开发利用的价值。植物药普遍具有Mn-SOD与Cu·Zn-SOD,本研究首先发现枸杞、宁夏枸杞、沙参和合子草具有Fe-SOD。酶粗提液的热稳定性明显优于纯化酶。