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Zusammenfassung Der Einfluss von Sekretin und Pankreozymin auf die Sekretion von Pepsin wurde in Hunden mit Heidenhain-Tasche untersucht. Die Hormone wurden ohne Narkose i.v. eingegeben. In allen Tieren verursachte Sekretin eine Steigerung der Pepsin-Sekretion im Magen; aber Pankreozymin hatte keinen Effekt. 相似文献
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Summary Mt. St. Helens' ash or U.S. Geological Survey silicate rock standards would replace FeCl3 as the limiting nutrient and repress the synthesis of rhodotorulic acid inRhodotorulia pilimanae cultures. 相似文献
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Zusammenfassung Der Einfluss von Cholecystokinin-Pankrcozymin auf die Sekretion von Pepsin wurde in Hunden mit Heidenhain-Tasche untersucht. Während submaximaler Pepsinstimulation mit Mecholyl verminderte i.v. Injektion von Cholecystokinin-Pankreozymin die Pepsin-Sekretion im Magen signifikant. Es wird vermutet, dass CCK-PZ Enterogastrone sein könnte. 相似文献
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Although information storage in the central nervous system is thought to be primarily mediated by various forms of synaptic plasticity, other mechanisms, such as modifications in membrane excitability, are available. Local dendritic spikes are nonlinear voltage events that are initiated within dendritic branches by spatially clustered and temporally synchronous synaptic input. That local spikes selectively respond only to appropriately correlated input allows them to function as input feature detectors and potentially as powerful information storage mechanisms. However, it is currently unknown whether any effective form of local dendritic spike plasticity exists. Here we show that the coupling between local dendritic spikes and the soma of rat hippocampal CA1 pyramidal neurons can be modified in a branch-specific manner through an N-methyl-d-aspartate receptor (NMDAR)-dependent regulation of dendritic Kv4.2 potassium channels. These data suggest that compartmentalized changes in branch excitability could store multiple complex features of synaptic input, such as their spatio-temporal correlation. We propose that this 'branch strength potentiation' represents a previously unknown form of information storage that is distinct from that produced by changes in synaptic efficacy both at the mechanistic level and in the type of information stored. 相似文献
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Van Houdt JK Nowakowska BA Sousa SB van Schaik BD Seuntjens E Avonce N Sifrim A Abdul-Rahman OA van den Boogaard MJ Bottani A Castori M Cormier-Daire V Deardorff MA Filges I Fryer A Fryns JP Gana S Garavelli L Gillessen-Kaesbach G Hall BD Horn D Huylebroeck D Klapecki J Krajewska-Walasek M Kuechler A Lines MA Maas S Macdermot KD McKee S Magee A de Man SA Moreau Y Morice-Picard F Obersztyn E Pilch J Rosser E Shannon N Stolte-Dijkstra I Van Dijck P Vilain C Vogels A Wakeling E Wieczorek D 《Nature genetics》2012,44(4):445-9, S1