Effect of particle size distribution on the microstructure,texture,and mechanical properties of Al–Mg–Si–Cu alloy

The effect of particle size distribution on the microstructure,texture,and mechanical properties of Al–Mg–Si–Cu alloy was investigated on the basis of the mechanical properties,microstructure,and texture of the alloy.The results show that the particle size distribution influences the microstructure and the final mechanical properties but only slightly influences the recrystallization texture.After the pre-aging treatment and natural aging treatment(T4 P treatment),in contrast to the sheet with a uniform particle size distribution,the sheet with a bimodal particle size distribution of large constituent particles and small dispersoids exhibits higher strength and a somewhat lower plastic strain ratio(r) and strain hardening exponent(n).After solution treatment,the sheet with a bimodal particle size distribution of large constituent particles and small dispersoids possesses a finer and slightly elongated grain structure compared with the sheet with a uniform particle size distribution.Additionally,they possess almost identical weak recrystallization textures,and their textures are dominated by CubeND {001}310 and P {011}122 orientations.     

Morphology and quantitative analysis of O phase during heat treatment of hot-deformed Ti_2AlNb-based alloy

A 1040°C-hot-deformed Ti_2AlNb-based alloy solution-treated at 950°C and aged at different temperatures was quantitatively investigated. The microstructure, size of the phase, and microhardness of the deformed alloys were measured. The results indicated that the microstructure of the deformed Ti_2AlNb-based alloy specimens comprise coarse O lath, fine O lath, equiaxed O/α_2, and acicular O phase. More O phase was generated in the deformed alloy after heat treatment because the acicular O phase was more likely to nucleate and grow along the deformation-induced crystal defects such as dislocations and subgrain boundaries. After deformation and subsequent heat treatment, the acicular O phase of the resultant alloy became finer compared to that of the undeformed alloy, and the acicular O phase became coarser and longer with the elevated aging temperature, while the width of the O lath exhibited unobvious variations. The hot deformation facilitated the dissolution of the O lath but accelerated the precipitation of the acicular O phase. When the 950°C-solution-treated deformed Ti_2AlNb-based alloy was then aged at 750°C for different periods, the phase content was nearly invariable, O and B2 phases eventually reached equilibrium, and the microstructure became stable and homogeneous.     

Developing anti-neoplastic biotherapeutics against eIF4F

Biotherapeutics have revolutionized modern medicine by providing medicines that would not have been possible with small molecules. With respect to cancer therapies, this represents the current sector of the pharmaceutical industry having the largest therapeutic impact, as exemplified by the development of recombinant antibodies and cell-based therapies. In cancer, one of the most common regulatory alterations is the perturbation of translational control. Among these, changes in eukaryotic initiation factor 4F (eIF4F) are associated with tumor initiation, progression, and drug resistance in a number of settings. This, coupled with the fact that systemic suppression of eIF4F appears well tolerated, indicates that therapeutic agents targeting eIF4F hold much therapeutic potential. Here, we discuss opportunities offered by biologicals for this purpose.     

不同冲击间隔分布下经典δ冲击模型的参数估计1

通过极大似然估计方法,对冲击时间间隔服从[0, b]上均匀分布、参数为λ的指数分布以及一般更新过程的经典δ冲击模型的参数δ、λ和b进行估计,得到了其相应的估计量。     

Deep cleaning of a metallurgical zinc leaching residue and recovery of valuable metals

Huge quantities of zinc leaching residues (ZLRs) generated from zinc production are dumped continuously around the world and pose a potential environmental threat because of their considerable amounts of entrained heavy metals (mainly lead). Most ZLRs have not been properly treated and the valuable metals in them have not yet been effectively recovered. Herein, the deep cleaning of a ZLR and recovery of valuable metals via a hydrometallurgical route were investigated. The cleaning process consists of two essential stages:acid leaching followed by calcium chloride leaching. The optimum conditions for extracting zinc, copper, and indium by acid leaching were a sulfuric acid concentration of 200 g·L-1, a liquid/solid ratio of 4:1 (mL/g), a leaching time of 2 h, and a temperature of 90℃. For lead and silver extractions, the optimum conditions were a calcium chloride concentration of 400 g·L-1, a pH value of 1.0, a leaching time of 1 h, and a temperature of 30℃. After calcium chloride leaching, silver and lead were extracted out and the lead was finally recovered as electrolytic lead by electrowinning. The anglesite phase, which poses the greatest potential environmental hazard, was removed from the ZLR after deep cleaning, thus reducing the cost of environmental management of ZLRs. The treatment of chlorine and spent electrolyte generated in the process was discussed.     

基于机械式变速器脱挡故障分析与预防

脱挡是汽车变速器的常见故障之一,笔者从机械式变速器脱挡故障现象入手,从整车和变速器两方面对脱挡故障展开分析,并提出了预防解决措施,提升机械式变速器可靠性能。     

概念精准与逻辑严密视角下对"密度"概念教学思路的再认识

"密度"作为初中物理引入最早、抽象程度最高的概念,历来都是教学的重点和难点,针对"密度"在日常教学中存在的症结,联系学生朴素认识,导入密度物理意义;直接比较物体质量,成功引发认知冲突;找出谬误产生根源,合理修正先前假设;结合具体实验数据,尝试诠释比值内涵;巧妙安排问题顺序,完成密度学习进阶4个环节,并对教学效果进行了相关的实证分析,教学效果很好.     

System optimization model of adoption of a new infrastructure with multi-resource and multi-demand sites

This study develops a conceptual system optimization model of adoption of a new infrastructure technology with multiple resource sites and multiple demand sites. With the model, this paper analyzes how the distance, spillover effect, demand, initial investment cost, and learning rate influence the adoption of the new infrastructure technology and presents optimization results of the model in different scenarios. The main findings of the study are: from the perspective of system optimization, (1) different distances among different resource-demand pairs will result in different adoption time of a new infrastructure; (2) technological spillover among different resource-demand pairs will accelerate the adoption of a new infrastructure; (3) it is hard to say that higher demand will pull faster adoption of a new infrastructure, and the optimal time of adopting of a new infrastructure is very sensitive to its technological learning rate.     

下一代密集WLAN网络干扰管理机制

在密集高效无线局域网部署场景中,针对传统802.11协议造成用户公平性差和吞吐量低的问题,提出一种以用户为中心的资源配置方法。该方法通过对用户进行识别分类,以用户为中心配置信道和功率,在保证用户公平性的前提下,最大化网络吞吐量。提出的功率控制机制和用户识别方法可以很简单的应用于现有无线局域网系统中。仿真结果表明,提出的资源配置方法平均提升单位基本服务集吞吐量47.3%,干扰最严重的基本服务集的吞吐量提升190%,每个基本服务集的边缘用户的吞吐量平均提升约74.3%。