行人运动仿真研究综述

行人运动仿真是近年来仿真领域研究的热点之一。从行人运动仿真的研究意义和研究内容出发,介绍了国内外行人运动仿真研究发展历程和研究现状,论述了行人运动仿真模型的三种类型,分析了成本效益元胞模型、元胞自动机模型、磁场力学模型、社会力学模型、排队网络模型五种典型的行人运动仿真模型的原理和适用条件。最后探讨了目前行人运动仿真研究中存在的问题及未来的发展前景。     

A cis-acting regulatory mutation causes premature hair graying and susceptibility to melanoma in the horse

In horses, graying with age is an autosomal dominant trait associated with a high incidence of melanoma and vitiligo-like depigmentation. Here we show that the Gray phenotype is caused by a 4.6-kb duplication in intron 6 of STX17 (syntaxin-17) that constitutes a cis-acting regulatory mutation. Both STX17 and the neighboring NR4A3 gene are overexpressed in melanomas from Gray horses. Gray horses carrying a loss-of-function mutation in ASIP (agouti signaling protein) had a higher incidence of melanoma, implying that increased melanocortin-1 receptor signaling promotes melanoma development in Gray horses. The Gray horse provides a notable example of how humans have cherry-picked mutations with favorable phenotypic effects in domestic animals.     

Existence of Equilibrium of Multiperiod Plan-Market Economy with the Stock Market

1　IntroductionWilliamA.ByrdhasstudiedtheexistenceofequilibriuminasimplemodelwithdistinctiveChineseeconomy(seeByrd,1989).Industrialgoodsaresubjecttomultipleallocationmechanism,includingvariousadministrativechannels,termedplanningsystemandcom-modityma...     

Protein Residue Contact Prediction Based on Deep Learning and Massive Statistical Features from Multi-Sequence Alignment

Sequence-based protein tertiary structure prediction is of fundamental importance because the function of a protein ultimately depends on its 3 D structure.An accurate residue-residue contact map is one of the essential elements for current ab initio prediction protocols of 3 D structure prediction.Recently,with the combination of deep learning and direct coupling techniques,the performance of residue contact prediction has achieved significant progress.However,a considerable number of current D...     

Sperm viability in the reproductive tract of females in a population of Sceloporus mucronatus exhibiting asynchronous reproduction

Asynchronous reproduction is a common phenomenon in high-elevation populations of lizards from Central México. Sperm storage in the reproductive tract of females is the mechanism for making oocyte fertilization possible. Our study addresses questions related to functional oviductal sperm storage of females mating on different dates throughout the reproductive season. A population of Sceloporus mucronatus with copulation in the summer and ovulation in the fall was chosen for this experiment. Eleven females that copulated in the field during June and 13 females that copulated in captivity during August were maintained in the laboratory until parturition. The number of pregnant females and the litter sizes produced in each experimental group were indicative of the viability of the stored sperm. Sperm stored in the reproductive tract of females were able to fertilize eggs after 4 months. No significant differences were found in the number of pregnant females between the 2 experimental groups nor in the litter sizes that they produced. We found that the amount of time sperm were held in the female reproductive tract (ca. 3 months) had no effect on the capacity of sperm to fertilize eggs. Histological examination of 8 oviducts collected before the mating season eliminated the possibility of sperm storage from one year to the next. In this system, sperm retention could have evolved as a response mechanism to deal with the asynchrony between sexes in the reproductive cycles. However, we cannot rule out alternative hypotheses.     

Attributes associated with probability of infestation by the pi?on ips, Ips confusus (Coleoptera: Scolytidae), in pi?on pine, Pinus edulis

We examined attributes of pi?on pine ( Pinus edulis ) associated with the probability of infestation by pi?on ips ( Ips confuses ) in an outbreak in the Coconino National Forest, Arizona. We used data collected from 87 plots, 59 infested and 28 uninfested, and a logistic regression approach to estimate the probability of infestation based on plot and tree-level attributes. Pi?on pine stand density index was a good predictor of the likelihood of infestation by pi?on ips at the plot level, and a cross-validation analysis confirmed that the model correctly classified 82% of the cases. Diameter at root collar and pi?on dwarf mistletoe infestation level were good predictors of individual tree infestation, and a cross-validation analysis indicated that the model correctly classified 72% of the cases. Results suggest that the occurrence of pi?on ips infestations may be related to stress factors associated with increased stocking and pi?on dwarf mistletoe infestations.     

Radon-Nikodym theorem in signed Loeb space

This paper gives the Radon-Nikodym theorem in signed Loeb space under 1-saturated nonstandard model. First,the nonstandard characterization of absolute continuity is discussed,on which Radon-Nikodym theorem in signed Loeb space is obtained. Then,some facts about a finite signed Loeb measure and its variation are shown.     

Amplitudes, rates, periodicities and causes of temperature variations in the past 2485 years and future trends over the central-eastern Tibetan Plateau

Amplitudes, rates, periodicities, causes and future trends of temperature variations based on tree rings for the past 2485 years on the central-eastern Tibetan Plateau were analyzed. The results showed that extreme climatic events on the Plateau, such as the Medieval Warm Period, Little Ice Age and 20th Century Warming appeared synchronously with those in other places worldwide. The largest amplitude and rate of temperature change occurred during the Eastern Jin Event (343-425 AD), and not in the late 20th century. There were significant cycles of 1324 a, 800 a, 199 a, 110 a and 2-3 a in the 2485-year temperature series. The 1324 a, 800 a, 199 a and 110 a cycles are associated with solar activity, which greatly affects the Earth surface temperature. The long-term trends (>1000 a) of temperature were controlled by the millennium-scale cycle, and amplitudes were dominated by multi-century cycles. Moreover, cold intervals corresponded to sunspot minimums. The prediction indicated that the temperature will decrease in the future until to 2068 AD and then increase again.     

A Lightweight Mobile RSVP for Unicast

This paper presents a lighter protocol, and it removes the multicast burdens from RSVP to adapt to unicast applications. At the same time, when RSVP is used in wireless networks, some issues about mobility raise popular concerns. The proposed protocol a lightweight mobile RSVP protocol, solves the problems by the following mechanisms： changeless flow identifier, a new state management and ＂refresh＂ mechanism.     

fMRI time series analysis based on stationary wavelet and spectrum analysis

The low signal to noise ratio (SNR) of functional MRI (fMRI) prefers more sensitive data analysis methods. Based on stationary wavelet transform and spectrum analysis, a new method with high detective sensitivity was developed for analyzing fMRI time series, which does not require any prior assumption of the characteristics of noises. In the proposed method, every component of fMRI time series in the different time-frequency scales of stationary wavelet transform was discerned by the spectrum analysis, then the components from noises were removed using the stationary wavelet transform, finally the components of real brain activation were detected by cross-correlation analysis. The results obtained from both simulated and in vivo visual experiments illustrated that the proposed method has much higher sensitivity than the traditional cross-correlation method.