可移动可弯曲输送机转向油缸控制方法研究

以可移动可弯曲输送机为研究对象,对输送机转弯过程中油缸的控制方法进行探讨。建立整机虚拟样机后,依次记录牵引车转弯角度;计算牵引车轨迹;计算各转向油缸对应伸出时间与位移;控制器控制辅助转向;最后完成轨迹跟踪。仿真分析证明该控制方法正确可行。     

Extremely low-coverage sequencing and imputation increases power for genome-wide association studies

Genome-wide association studies (GWAS) have proven to be a powerful method to identify common genetic variants contributing to susceptibility to common diseases. Here, we show that extremely low-coverage sequencing (0.1-0.5×) captures almost as much of the common (>5%) and low-frequency (1-5%) variation across the genome as SNP arrays. As an empirical demonstration, we show that genome-wide SNP genotypes can be inferred at a mean r(2) of 0.71 using off-target data (0.24× average coverage) in a whole-exome study of 909 samples. Using both simulated and real exome-sequencing data sets, we show that association statistics obtained using extremely low-coverage sequencing data attain similar P values at known associated variants as data from genotyping arrays, without an excess of false positives. Within the context of reductions in sample preparation and sequencing costs, funds invested in extremely low-coverage sequencing can yield several times the effective sample size of GWAS based on SNP array data and a commensurate increase in statistical power.     

摩托车声品质评价的神经网络方法

针对声品质评价过程中线性回归模型评价结果的不足,采用BP神经网络对人的主观评价结果进行预测.采集摩托车在不同发动机转速下驾驶员耳旁的声信号样本,采用分组成对比较法进行主观评价试验,选取了响度、尖锐度、粗糙度作为神经网络模型输入参数,结合主观评价结果对模型进行训练与检验,并与线性回归模型输出结果进行比较.结果表明,选取驾驶员双耳响度、尖锐度、粗糙度作为模型输入能够较为准确地反映人耳对摩托车噪声的主观感觉.     

Frequent mutations of chromatin remodeling genes in transitional cell carcinoma of the bladder

Transitional cell carcinoma (TCC) is the most common type of bladder cancer. Here we sequenced the exomes of nine individuals with TCC and screened all the somatically mutated genes in a prevalence set of 88 additional individuals with TCC with different tumor stages and grades. In our study, we discovered a variety of genes previously unknown to be mutated in TCC. Notably, we identified genetic aberrations of the chromatin remodeling genes (UTX, MLL-MLL3, CREBBP-EP300, NCOR1, ARID1A and CHD6) in 59% of our 97 subjects with TCC. Of these genes, we showed UTX to be altered substantially more frequently in tumors of low stages and grades, highlighting its potential role in the classification and diagnosis of bladder cancer. Our results provide an overview of the genetic basis of TCC and suggest that aberration of chromatin regulation might be a hallmark of bladder cancer.     

离心压缩机的扩压器内部流场分析及其结构优化

首先对等宽型无叶扩压器内部流动情况进行了较为详细的分析,在此分析基础上进行了两处改进：1）将等宽型无叶扩压器改为收缩型无叶扩压器;2）在原等宽无叶扩压器中加装导向叶片,并利用CFD软件（FLUENT）对改进后的扩压器内部流场进行数值模拟。从模拟结果上看：改进后的扩压器其内部流动不均匀情况得到明显改善,拥有了良好的气动性,从而有效地提高了压缩机整体性能。     

掘进机新型液压油箱的设计与应用

液压油液的温升与污染是制约液压系统可靠性与液压元件寿命的关键。为了减小因油箱的设计缺陷而引起的油液污染速度快,温升高的问题,对EBZ230掘进机泵站闭式油箱进行改进设计。通过样机的应用与实验证明了这种新型的油箱系统能更有效地降低油液的污染速度与等级、更平稳更快速地冷却油液,对提高整机液压系统可靠性与稳定性有非常积极的意义。该油箱结构亦可应用于有着相似要求的液压设备中,具有较高的推广价值。     

Fault-Tolerant Design for Data Efficient Retransmission in WiNoC

There is a sharp decline in the network performance when the wireless link fails as a data path in the Wireless Network-on-Chip(WiNoC).To counteract this problem,we propose a fault-tolerance mechanism for the efficient retransmission of data in the WiNoC.When an error is detected in the data transmission process,this mechanism works to feed back the fault information to the source node in real time via fault signal lines.In the source node,the highest transmission priority is assigned to the backup retransmitted data,and the corresponding direct link is positioned to enable the data packet for its efficient retransmission to the destination node,thereby ensuring efficiency in fault tolerance.Additionally,we have improved the receiving port of the wireless router,added the corresponding redundant buffers and mux,and dynamically selected the retransmitted non-faulty data packets to be written to the local router in order to avoid the disorderly retransmission of the data packets.The evaluation results of this paper demonstrate that compared with the methods which are under different fault conditions,this fault-tolerant method drastically improves the data throughput rate,reduces the delay,effectively guarantees the reliability of the network,and improves the system performance.     

Integrating electromagnetic surface and antenna array for reflection suppression and excellent radiation

The electromagnetic surface antenna array(EMSAA)has been proposed for obtaining reflection suppression and ex-cellent radiation simultaneously.The antenna with ...