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291.
I. J. Miller N. K. McCallum C. M. Kirk B. M. Peake 《Cellular and molecular life sciences : CMLS》1982,38(2):230-231
Summary The free radical oxidation of 1 and 6-tetrahydrocannabinol has been examined by spin trapping techniques and intermediates that would lead to cannabinol have been trapped. The 1st step in the oxidation of 1-THC involves the removal of 3-H, while for 6-THC, either 2-H or 5-H. Intermediates were isolated which could be pyrolysed to the diene and cannabinol. 相似文献
292.
I. Yuli S. Incerpi P. Luly M. Shinitzky 《Cellular and molecular life sciences : CMLS》1982,38(9):1114-1115
Summary Basal and insulin-stimulated transport of 2-deoxy glucose and of -aminoisobutyric acid in mouse 3T3 fibroblasts were modulated by increasing the lipid microviscosity of the cell plasma membrane. The kinetics indicate that the insulin effect is induced either by recruitment of new transport carriers or by reduction of the translocation activation energy.This investigation was supported by grant No.5-R01-CA-27471-02, awarded by the National Cancer Institute, Department of Health, Education and Welfare. 相似文献
293.
S. Leoni P. Luly M. T. Mangiantini S. Spagnuolo 《Cellular and molecular life sciences : CMLS》1982,38(1):102-104
Summary The effect of cholesterol and fatty acid treatment in vitro was tested on rat liver plasma membrane-bound enzymes and lipid fluidity. The observed alterations of membrane fluidity affect both (Na+–K+)-ATPase and Mg2+-ATPase activities but not 5-nucleotidase; basal adenylate cyclase as well as its hormonal sensitivity were differentially affected by changes of membrane microenvironment.This investigation was partially supported by the Italian National Research Council. 相似文献
294.
G. Zamboni E. Perez P. L. Parmeggiani 《Cellular and molecular life sciences : CMLS》1982,38(10):1188-1189
Summary In rats adapted to a 1212 h light-dark (LD) schedule, cyclic AMP concentration in the preoptic region showed a L minimum and D maximum. No significant fluctuations were observed in the parietal cortex.Supported by grant No. 79.01946.04 awarded by the National Research Council (CNR), Rome, Italy. 相似文献
295.
Captopril (SQ 14,225): In vitro and in vivo influence on the proliferative response of rat lymphocytes 总被引:1,自引:0,他引:1
Lise Binderup E. Bramm E. Arrigoni-Martelli 《Cellular and molecular life sciences : CMLS》1982,38(3):399-401
Summary Captopril in vitro (50–500 g/ml) increased3H-TdR incorporation in unstimulated and mitogen-stimulated cultures of rat lymphocytes. Unseparated spleen and lymph node cells of rats orally treated with captopril (50 mg/kg/day×4) showed decreased basal and mitogen stimulated3H-TdR incorporation. The removal of macrophages abrogated this inhibitory effect. Leucine aminopeptidase activity of macrophages was reduced — in vivo and in vitro — by captopril.Acknowledgments. The authors thank the Squibb Institute for Medical Research for the gift of Captopril. The excellent technical assistance of Ms B. Hasselriis, Ms B. Rumler and Ms E. Greve Petersen is gratefully acknowledged. 相似文献
296.
M. Karydis 《Cellular and molecular life sciences : CMLS》1982,38(10):1185-1186
Summary The importance of phytoplankton in stabilizing oil-in-water emulsion and affecting hydrocarbon distribution in the sea was studied by using marine diatoms. All microalgae tested increased emulsion stability and favored the presence of polycyclic aromatics in the sea water. 相似文献
297.
Summary Leydig cell nuclear area and
5-3-hydroxysteroid dehydrogenase activity were increased in the testis ofBufo melanostictus 2 days after a single short-term cold exposure. Both parameters returned to normal values 4 days later. 相似文献
298.
Summary The defense secretion of soldiers ofReticulitermes lucifugus has been shown to contain, predominantly, (R)-(–)-(E,E)-geranyllinalool together with germacrene A and -farnesene.This report covers part of a collaborative study with J.-L. Clément, Lab. d'Evolution, Université P. et M. Curie, Paris, to whom we are grateful for supplies of material and discussions. We also thank Dr O.T. Jones for collections ofReticulitermes lucifugus. 相似文献
299.
Genetic polymorphisms and intrauterine development. Evidence of decreased heterozygosity in light-for-dates human newborn babies 总被引:2,自引:0,他引:2
E. Bottini F. Gloria-Bottini P. Lucarelli A. Polzonetti F. Santoro A. Varveri 《Cellular and molecular life sciences : CMLS》1979,35(12):1565-1567
Summary In 2 independent samples of low-birth-weight infants the proportion of females and homozygotes for a series of polymorphic systems was higher in light-for-dates than in preterm babies. The observation seems to give support to the hypothesis that homozygosity for normal polymorphisms may decrease in general intrauterine growth rate. Since it is known that survival rate is strongly related to birth weight, a correlation between growth retardation and homozygosity may have a major role in the maintenance of such polimorphisms.We thank Prof. L. Ginzburg for helpful comments. 相似文献
300.
Blocking by picrotoxin of nigra-evoked inhibition of neurons of ventromedial nucleus of the thalamus
Summary The transmitter substance released by nigro-thalamic fibres is proposed to be -aminobutyric acid, since picrotoxin blocked nigra-evoked monosynaptic inhibition of thalamic neurons.Supported by grants Nos 212009 and 311410 from Ministry of Education of Japan.The authors wish to thank Dr Marjorie Anderson, University of Washington, Seattle, for improving the English. 相似文献