排序方式： 共有24条查询结果，搜索用时 0 毫秒
21.
Eeles RA Kote-Jarai Z Giles GG Olama AA Guy M Jugurnauth SK Mulholland S Leongamornlert DA Edwards SM Morrison J Field HI Southey MC Severi G Donovan JL Hamdy FC Dearnaley DP Muir KR Smith C Bagnato M Ardern-Jones AT Hall AL O'Brien LT Gehr-Swain BN Wilkinson RA Cox A Lewis S Brown PM Jhavar SG Tymrakiewicz M Lophatananon A Bryant SL;UK Genetic Prostate Cancer Study Collaborators;British Association of Urological Surgeons' Section of Oncology;UK ProtecT Study Collaborators Horwich A Huddart RA 《Nature genetics》2008,40(3):316-321
Prostate cancer is the most common cancer affecting males in developed countries. It shows consistent evidence of familial aggregation, but the causes of this aggregation are mostly unknown. To identify common alleles associated with prostate cancer risk, we conducted a genome-wide association study (GWAS) using blood DNA samples from 1,854 individuals with clinically detected prostate cancer diagnosed at 相似文献
22.
Antibiotic bioassay by flow microcalorimetry 总被引：1，自引：0，他引：1
A. E. Beezer R. J. Miles Elizabeth J. Shaw Lynne Vickerstaff 《Cellular and molecular life sciences : CMLS》1980,36(9):1051-1052
Summary A rapid, sensitive microcalorimetric bioassay of good reproducibility has been developed for the antibiotics penicillin-G, carbenicillin, ampicillin and cefoxitin. The use of growing organisms as responding agents allows discussion of the results for systems which may involve biological fluids.Acknowledgment. We thank the Department of Health and Social Security for a grant to support this work. 相似文献
23.
古人类化石是探索人类起源和演化的重要研究材料,由于人类化石标本的珍贵性,不可能对其进行实体解剖,传统的研究方法只能停留在化石的外表形态特征的研究上．CT技术为古人类学的发展开辟了广阔的前景．目前,CT技术在中国古人类化石上的应用还很薄弱,很多具体的工作还没有开展．为了对CT技术在古人类学上的应用情况有个全面、系统的了解,文中对近年来CT在国际古人类学界的研究及进展作综述,包括：化石标本的虚拟复原;颅内模及脑形态特征的研究;骨骼生物力学分析;木乃伊及早期人类的身体健康状况;骨骼和牙齿的微细解剖结构．对未来工作加以展望． 相似文献
24.
Scherer SE Muzny DM Buhay CJ Chen R Cree A Ding Y Dugan-Rocha S Gill R Gunaratne P Harris RA Hawes AC Hernandez J Hodgson AV Hume J Jackson A Khan ZM Kovar-Smith C Lewis LR Lozado RJ Metzker ML Milosavljevic A Miner GR Montgomery KT Morgan MB Nazareth LV Scott G Sodergren E Song XZ Steffen D Lovering RC Wheeler DA Worley KC Yuan Y Zhang Z Adams CQ Ansari-Lari MA Ayele M Brown MJ Chen G Chen Z Clerc-Blankenburg KP Davis C Delgado O Dinh HH Draper H Gonzalez-Garay ML Havlak P Jackson LR Jacob LS 《Nature》2006,440(7082):346-351
Human chromosome 12 contains more than 1,400 coding genes and 487 loci that have been directly implicated in human disease. The q arm of chromosome 12 contains one of the largest blocks of linkage disequilibrium found in the human genome. Here we present the finished sequence of human chromosome 12, which has been finished to high quality and spans approximately 132 megabases, representing approximately 4.5% of the human genome. Alignment of the human chromosome 12 sequence across vertebrates reveals the origin of individual segments in chicken, and a unique history of rearrangement through rodent and primate lineages. The rate of base substitutions in recent evolutionary history shows an overall slowing in hominids compared with primates and rodents. 相似文献