ePTFE人工血管管壁结构及其体外性能的试验研究

对国内外两组膨体聚四氟乙烯(ePTFE)人工血管从管壁结构、理化性能和生物力学性能进行对比研究.通过试验研究两组人造血管管壁的宏观及微观结构、表面润湿性、结晶度和融熔温度、周/轴向拉伸、顶破拉伸以及手术线固位强力,对比两组样品的性能差异,并分析了导致差异的可能原因,讨论了管壁结构、理化性能与力学特性之间的关系.研究结果表明,国产和进口ePTFE人工血管试样均为双层结构,两者都有良好的疏水性表面和抗水渗透性.但进口试样具有更加规整均匀的节点和纤维形态结构,有利于人工血管的生物耐久性.     

微波接力组网的节点再优化研究

为进一步完善常规方法构建的微波接力网组网拓扑,提出了一种基于最优链路集的网络节点再优化方法。该方法综合考虑节点吸引系数、链路衰落概率、节点通信冗余等因素,借助网络拓扑优化的思想,采用遗传算法构造了微波接力网的最优链路集;以节点在该集合中的度为依据,通过对节点的合理排序,以部分用户节点代替非必要的干线节点,完善了组网拓扑。在修改链路和节点价值集后,该方法还可解决其他网络干线、中继节点的选择问题。     

峰值电量约束下的场桥能耗最小化问题研究

随着化石能源的大量使用带来的环境污染问题日益严峻,关注能源使用效率的集装箱港口绿色化运营研究成为近年来的热点之一.本文以集装箱堆场中需要执行预倒箱作业的场桥为研究对象,考虑场桥不同运行状态下的单位时间电量需求不同以及峰值电量实时约束,建立了以总能耗最小化为目标的多场桥调度问题的混合整数规划数学模型.继而,将关键变量利用非连续贝和连续贝两种不同的方式进行编码,将次级变量利用启发式规则进行解码,并设计了相对应的遗传算法交叉与变异方法.数值实验表明,连续贝编码方法表现更为优异;通过与Cplex在小规模算例中的比较,与粒子群算法及人工蜂群算法在大规模算例中的比较,验证了所设计遗传算法的有效性.同时,通过与传统策略的对比,表明本模型可以同时实现能耗总需求与峰值需求两方面的优化,从而可以为港口管理人员在不影响既定日常运营工作的前提下降低能源成本提供科学有效的指导.     

C2H2锌指蛋白药物递送技术的研发与应用

锌指蛋白是真核生物中广泛存在的转录因子，在基因的表达调控中起着重要作用。近期研究发现，C₂H₂类型的锌指蛋白(通过两个半胱氨酸和两个组氨酸螯合锌离子)可通过巨胞饮进入哺乳动物细胞。进一步的研究发现C₂H₂锌指蛋白可介导多种模式蛋白质及药物蛋白质的高效细胞递送，其细胞穿透效率亦高于传统的细胞穿膜肽。文章介绍了锌指蛋白的基本生物学信息和其细胞穿透特性，并讨论C₂H₂ 锌指蛋白在大分子药物递送中的应用。     

Preparation and Mechanical Properties of a Novel Textile Pad for Wound Debridement

Various types of wound debridement approaches are currently available in clinical practice such as autolytie, enzymatic. biodebridement, mechanical, and surgical debridemenl techniques. A critical look at these various options can explain their potential but also their limitations. In this study, a novel textile pad, which is composed of polyester filaments on the fleecy side and a bioeompatible coating on the opposite side, was made to provide a safe, inexpensive, easier and especially more efficient debridement process that can be used in all healthcare settings by all healthcare practitioners. Eighteen kinds of samples were prepared with different pile density, ground yarn count and coating amount. Dimensional morphology, stitch density, mass per unit area and mechanical properties were investigated to study the intrinsic relationship of structure and properties of textile pad for wound debridement. Results showed that tensile strength and suturing strength at piped site increased obviously with the increment of ground yarn count, while the amount of coating could also have a slight impact on these two properties. However, compressive load was mainly affected by pile density, with no obvious relation to ground yarn count and coating amount.     

教育实习问题分析与改进对策

本文针对目前大学生对教育实习的重要性认识不足、对中学新课程改革状况了解不够、教育实习缺少科学的评价机制等问题,从中学教育对未来教师的需要出发,提出加强职业理想教育、建立大学与中学沟通机制、强化教学基本功训练、培养人文素养和建立科学评价机制等对策,供改进大学教育实习工作参考.     

Upwind finite volume element methods for one-dimensional semiconductor device

A fully discrete implicit Euler upwind finite volume element method is derived and studied for one-dimensional semiconductor device. Upwind scheme is introduced to deal with the convection-dominated diffusion equations in the semiconductor model. With different time steps for the electrostatic potential and the other unknown quantities, the computational procedure of the method is obtained. The local mass conservation laws are preserved under the framework of the upwind finite volume element schemes. A first-order accuracy in the L ²-norm is proved. Numerical experiments are given to validate the usefulness and efficiency of the method.     

论美国保险法合理期待原则的产生与新发展

合理期待原则是美国保险法为规范保险合同最新发展的原则,该原则针对的是保险合同订立中不利于投保人、被保险人的特点而提出,该原则最新的发展动向是法院在适用中与第二次《合同法重述》关于格式合同的适用例外规定相结合,为我国保护保险消费者提供了新的思路。     

Self-alignment of full skewed RSINS：observability analysis and full-observable Kalman filter

Traditional orthogonal strapdown inertial navigation sys-tem （SINS） cannot achieve satisfactory self-alignment accuracy in the stationary base： taking more than 5 minutes and al the iner-tial sensors biases cannot get ful observability except the up-axis accelerometer. However, the ful skewed redundant SINS （RSINS） can not only enhance the reliability of the system, but also improve the accuracy of the system, such as the initial alignment. Firstly, the observability of the system state includes attitude errors and al the inertial sensors biases are analyzed with the global perspective method： any three gyroscopes and three accelerometers can be assembled into an independent subordinate SINS （sub-SINS）;the system state can be uniquely confirmed by the coupling connec-tions of al the sub-SINSs;the attitude errors and random constant biases of al the inertial sensors are observable. However, the ran-dom noises of the inertial sensors are not taken into account in the above analyzing process. Secondly, the ful-observable Kalman filter which can be applied to the actual RSINS containing random noises is established; the system state includes the position, ve-locity, attitude errors of al the sub-SINSs and the random constant biases of the redundant inertial sensors. At last, the initial self-alignment process of a typical four-redundancy ful skewed RSINS is simulated： the horizontal attitudes （pitch, rol ） errors and yaw error can be exactly evaluated within 80 s and 100 s respectively, while the random constant biases of gyroscopes and accelero-meters can be precisely evaluated within 120 s. For the ful skewed RSINS, the self-alignment accuracy is greatly improved, mean-while the self-alignment time is widely shortened.     

丁善德钢琴创作晚期的艺术特色——试析《小序曲与赋格四首》之三“序曲-雀跃”

钢琴套曲《小序曲与赋格四首》创作于改革开放之后,也是作曲家丁善德先生钢琴音乐创作晚期较有代表性的一首作品。本文以其中第三首序曲《雀跃》为例,从作品的结构、调性格局、创作技法等方面来探讨丁善德先生这一时期的创作风格和艺术特色及其对中国钢琴音乐发展所产生的影响。