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171.
Kröll J Darmo J Dhillon SS Marcadet X Calligaro M Sirtori C Unterrainer K 《Nature》2007,449(7163):698-701
Lasers are usually described by their output frequency and intensity. However, laser operation is an inherently nonlinear process. Knowledge about the dynamic behaviour of lasers is thus of great importance for detailed understanding of laser operation and for improvement in performance for applications. Of particular interest is the time domain within the coherence time of the optical transition. This time is determined by the oscillation period of the laser radiation and thus is very short. Rigorous quantum mechanical models predict interesting effects like quantum beats, lasing without inversion, and photon echo processes. As these models are based on quantum coherence and interference, knowledge of the phase within the optical cycle is of particular interest. Laser radiation has so far been measured using intensity detectors, which are sensitive to the square of the electric field. Therefore information about the sign and phase of the laser radiation is lost. Here we use an electro-optic detection scheme to measure the amplitude and phase of stimulated radiation, and correlate this radiation directly with an input probing pulse. We have applied this technique to semiconductor quantum cascade lasers, which are coherent sources operating at frequencies between the optical (>100 THz) and electronic (<0.5 THz) ranges. In addition to the phase information, we can also determine the spectral gain, the bias dependence of this gain, and obtain an insight into the evolution of the laser field. 相似文献
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LEONARD Michel 《中山大学学报(自然科学版)》2007,46(Z2):126-129
The science of services constitutes a breakthrough in the traditional way of thinking of the place of informatics in the economic development of a State,a Region,an enterprise and consequently in the teaching programs.The question is no more only a question of computer science.We are in front of a more complex situation,which requires not only a multidisciplinary approach,but an interoperable approach at the intellectual level.This paper is an introduction to this complexity and it is also an attempt to propose crucial questions about the new bachelor programs and master programs. 相似文献
175.
本书是法国埃库勒理工学院一套著名的教科书中的一本.是作者为高年级大学生讲授原子核物理相关的一些专题课发展而成的教材。作者们认为大多数核现象都可以从基于泡利原理与库仑势垒的一些简单的论证理解。因此本书并不打算对于核理论现代发展深人讨论,而是把重点放在核物理学各方面的实际应用。本书充分利用了从网上可以得到的大量核物理的实验数据资源。 相似文献
176.
Platelet shape change and aggregation 总被引:1,自引:0,他引:1
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Summary A combined treatment involving a radio-sensitizing chemical and low doses of X-rays was investigated. Small quantities of iodoacetamide can cause an increase in the radiation damages of rat embryos. The possibility of inhibition of postirradiation repair mechanisms is discussed. 相似文献
179.
Van Laere AS Nguyen M Braunschweig M Nezer C Collette C Moreau L Archibald AL Haley CS Buys N Tally M Andersson G Georges M Andersson L 《Nature》2003,425(6960):832-836
Most traits and disorders have a multifactorial background indicating that they are controlled by environmental factors as well as an unknown number of quantitative trait loci (QTLs). The identification of mutations underlying QTLs is a challenge because each locus explains only a fraction of the phenotypic variation. A paternally expressed QTL affecting muscle growth, fat deposition and size of the heart in pigs maps to the IGF2 (insulin-like growth factor 2) region. Here we show that this QTL is caused by a nucleotide substitution in intron 3 of IGF2. The mutation occurs in an evolutionarily conserved CpG island that is hypomethylated in skeletal muscle. The mutation abrogates in vitro interaction with a nuclear factor, probably a repressor, and pigs inheriting the mutation from their sire have a threefold increase in IGF2 messenger RNA expression in postnatal muscle. Our study establishes a causal relationship between a single-base-pair substitution in a non-coding region and a QTL effect. The result supports the long-held view that regulatory mutations are important for controlling phenotypic variation. 相似文献
180.
Mutations in IRF6 cause Van der Woude and popliteal pterygium syndromes 总被引:25,自引:0,他引:25
Kondo S Schutte BC Richardson RJ Bjork BC Knight AS Watanabe Y Howard E de Lima RL Daack-Hirsch S Sander A McDonald-McGinn DM Zackai EH Lammer EJ Aylsworth AS Ardinger HH Lidral AC Pober BR Moreno L Arcos-Burgos M Valencia C Houdayer C Bahuau M Moretti-Ferreira D Richieri-Costa A Dixon MJ Murray JC 《Nature genetics》2002,32(2):285-289