醋酸乌利司他假多晶型分子热分解机理及动力学

通过冷却结晶实验制备醋酸乌利司他以乙醇为溶剂的假多晶型晶体.热重实验结果表明醋酸乌利司他假多晶型在升温过程中包含溶剂脱除与分子热分解2个过程.利用非等温热重法对醋酸乌利司他假多晶型的分子热分解过程机理及其动力学进行研究.基于不同热分解机理所对应的反应动力学机理函数,结合醋酸乌利司他假多晶型非等温热分解实验数据,计算估测醋酸乌利司他假多晶型分子热分解的机理,并计算得到这一过程所对应的热分解动力学方程.     

西部少数民族地区县域经济发展实证研究—以贵州省玉屏侗族自治县为例

采用1995-2010年贵州省玉屏侗族自治县城镇化水平、第三产业增加值、招商引资数量、人均教育支出、R＆D经费投入共五项的时间序列数据,运用普通最小二乘法的实证研究方法,对玉屏县县域经济的增长进行计量研究。结果显示：城镇化水平、第三产业增加值、招商引资数量、人均教育支出、R＆D经费投入都对玉屏县县域经济的增长有正向推动作用,其中招商引资数量推动作用最大,R＆D经费投入推动作用最小。最后根据研究结论提出相应建议。     

竖向荷载下分布式连接全装配RC楼盖横板向受力性能试验研究

为研究分布式连接全装配RC楼盖(DCPCD)横板向受力性能,进行了6个足尺DCPCD试件和2个现浇试件在竖向均布荷载下的静载试验,分析了试件的破坏模式、挠曲变形和应变发展规律.结果表明,DCPCD板缝连接件传力性能良好,试件弯曲刚度小于现浇试件,没有明显的塑性工作阶段,且较早进入弹塑性.DCPCD横板向挠曲变形以板缝变...     

热源塔液气比优化分析与实验研究

针对夏热冬冷地区对冬夏两季双高效供冷/供热空调设备的需求,提出了采用热源塔热泵达到夏季高效供冷而冬季高效供热效果的解决方法.对热源塔热泵的原理和工作过程及其与冷水机组和空气源热泵的异同点进行了分析,建立了叉流式热源塔装置,并在不同室外空气参数情况下,以水和溶液(乙二醇水溶液)作为介质且在不同液气比时,对热源塔换热性能进...     

利用弧声信号的电弧预警保护系统设计

基于开关柜电压在电弧故障时电压变化率在零区时最大的规律,研制一种弧声信号的电弧预警保护系统.根据电弧发生燃弧现象之前会有比较明显的弧声信号的情况,用相应的声音传感器将电弧声音从复杂的背景噪声中提取出来,经过信号调理电路和计算机软件系统的运算,设定合适的幅值阈值,实现对故障电弧的报警.实验结果表明,设计的电弧预警保护系统效果良好.     

用离散型最小二乘法解混合边界矩形薄板的弯曲问题

混合边界矩形薄板的弯曲问题一般不易得到精确解。1960年日本学者曾给出部分简支,部分固定的混合边界矩形板的解答,其数学演算冗杂,而且是有限项的级数解。1984年国内有人用广义伽辽金法求解了此问题,但算式要积分,仍较麻烦。本文用加权残数法中的离散型最小二乘法求解此问题,提出的挠度试函数精确满足板内的微分方程,部分满足边界条件。因此,只需在部分边界上配点即可,算式简单,工作量少,算例结果良好。     

Construction of a linkage map and QTL mapping for fiber quality traits in upland cotton (Gossypium hirsutum L.)

With the development in spinning technology, the improvement of cotton fiber quality is becoming more and more important. The main objective of this research was to construct a high-density genetic linkage map to facilitate marker assisted selection for fiber quality traits in upland cotton (Gossypium hirsutum L.). A genetic linkage map comprising 421 loci and covering 3814.3 cM, accounting for approximately 73.35% of the cotton genome, was constructed using an F2 population derived from cross GX1135 (P 1 )×GX100-2 (P 2 ). Forty-four of 49 linkage groups were assigned to the 26 chromosomes. Fiber quality traits were investigated in F2 population sampled from individuals, and in F2:3 , and F2:4 generations sampled by lines from two sites and one respectively, and each followed a randomized complete block design with two replications. Thirty-nine quantitative trait loci were detected for five fiber quality traits with data from single environments (separate analysis each): 12 for fiber length, five for fiber uniformity, nine for fiber strength, seven for fiber elongation, and six for fiber micronaire, whereas 15 QTLs were found in combined analysis (data from means of different environments in F2:3 generation). Among these QTLs, qFL-chr5-2 and qFL-chr14-2 for fiber length were detected simultaneously in three generations (four environments) and verified further by combined analysis, and these QTLs should be useful for marker assisted selection to improve fiber quality in upland cotton.     

社会困境中博弈决策的理论模型与神经机制

简要介绍社会困境的涵义,详细阐述博弈决策的理性选择理论、认知转换理论和生物进化理论,并且从认知控制、社会认知以及奖励预期3个过程揭示博弈决策的神经机制.未来研究应力求突破先前理论模型的不足,深入考察个体合作行为的神经机制,并向实际应用领域发展.     

Overexpression of N-cadherin is correlated with metastasis and worse survival in colorectal cancer patients

N-cadherin is related to the progression and metastases of several solid carcinomas. However, it was still unclear whether N-cadherin is overexpressed in colorectal malignant tumors that have stronger malignant tendency. In this study, we used immunohistochemistry to detect the expression patterns of N-cadherin in both the primary tumors and their normal mucosa tissues of 120 patients with colorectal cancer. We revealed that N-cadherin was expressed in 78.3% (94/120) of colorectal tumor tissues and in only 9.2% (11/120) of paired distant normal mucosa tissues with a significant difference (P=0.000). The low, moderate, and high expression of N-cadherin protein was 42.5%, 30.8%, and 26.7%, respectively. N-cadherin overexpression was associated with advanced TNM stage, lymph nodes metastasis and distant metastasis (P<0.05). Patients with N-cadherin overexpressed showed the obvious lower overall survival rate than those with moderate and low expression, and patients with low expression had a better survival rate than those with moderate and high expression (P<0.05). In conclusion, high N-cadherin expression may lead to tumor aggressiveness and metastatic potential in colorectal cancer, and may prove to be a possible prognostic factor.     

PACS与HIS融合的实践

简要介绍了基于国际通用DICOM标准的PACS系统与HIS系统的融合技术,分析了几种融合技术的优缺点,并以解放军第264医院PACS系统与HIS系统的融合为例,探讨了PACS系统与HIS系统融合的具体实现。