LDLR基因Ava Ⅱ位点多态性与高甘油三酯血症的相关性

研究了LDLR基因外显子13中Ava Ⅱ位点多态性在宁夏回族自治区正常回、汉族人群及高甘油三酯血症患者中的分布频率,分析探讨了该住点多态性是否存在于宁夏回、汉族居民中,以及基因型与甘油三酯含量之间的相关性.应用聚合酶链式反应-限制性内切酶片段长度多态性(PCR-RFLP)的方法,对214例健康样本(回族102例,汉族112例)和212例高甘油三酯血症患者样本(回族88例,汉族124例)的低密度脂蛋白受体(LDLR)基因的多态性进行了检测.结果发现,在宁夏地区回、汉族人群中存在着Ava Ⅱ多态性位点,回、汉族居民间存在着明显差异,健康人群与高甘油三酯血症人群之间该位点基因型存在着显著差异.由此说明,Ava Ⅱ多态性位点可以作为宁夏回、汉族的遗传标记,而且该位点与高甘油三酯血症有相关性.     

接受理论视角下的文学翻译创造性叛逆

文学翻译除了要传达原作中的基本信息外,更重要的是把文学作品中的审美信息也传达出来,译者必须发挥他的艺术创造才能去接近和再现原作。而在大多数情况下,译者在达到这一主观愿望的同时客观上会造成对原作的背离,这就是我们常说的文学翻译的创造性叛逆。本文将运用接受理论中的三个核心概念——"期待视野"、"具体化"、"前理解"对文学翻译的创造性叛逆现象进行阐释。     

溴化1-己基-3-甲基咪唑的制备和电导率研究

用溴代正己烷与N-甲基咪唑反应制备了溴化1-己基-3-甲基咪唑离子液体;对离子液体进行了红外光谱分析和结构表征。测定了离子液体[HMI M]Br在温度为283.15 K至313.15 K之间的电导率,将测得的电导率值σ对(T-273.15)进行拟合,得出拟合方程和相关系数,结果表明离子液体[HMI M]Br的电导率随温度的升高而增大,符合VTF经验方程。离子液体[HMI M]Br在水、乙醇、乙腈等溶剂中的紫外吸收光谱分析结果表明,溶剂的极性和酸碱性对离子液体[HMI M]Br的紫外吸收光谱均有影响。     

Computation model and improved ACO algorithm for p//T

Scheduling jobs on parallel machines to minimize the total tardiness (p//T) is proved to be NP hard. A new ant colony algorithm to deal with p//T (p//T ACO) is addressed, and the computing model of mapping p//T to the ant colony optimization environment is designed. Besides, based on the academic researches on p//T, some new properties used in the evolutionary computation are analyzed and proved. The theoretical analysis and comparative experiments demonstrate that p//T ACO has much better performance and can be used to solve practical large scale problems efficiently.     

M-余平坦模和凝聚环

用同调代数的方法对M-余平坦模进行了讨论,得到了有关M-余平坦模的几个结论,同时得出了M-余平坦模和凝聚环的关系.     

大学实验中引入情境教学初探

阐明了情境教学的含义,分析了国内高校大学化学实验课程中存的在问题,通过教学实践,指出了情境创设的途径,提出了一些可操作性建议.     

胸主动脉夹层动脉瘤腔内隔绝术10例分析

目的:讨论胸主动脉夹层动脉瘤腔内隔绝术的术前注意要点.方法:回顾2004年12月至2008年12月应用带膜支架腔内隔绝术治疗DebakeyⅢ型胸主动脉夹层动脉瘤10例资料.结果:10例患者带膜支架腔内隔绝破口封堵均一次成功.结论:带膜支架腔内隔绝术适应于DebakeyⅢ型胸主动脉夹层动脉瘤,应注意手术时机及胸腹主动脉部成角及内径影响带膜支架的置入.     

Efficacy of anti-CD20 chimeric Fab’ fragment on proliferation of B lymphoma cells

The variable domain of heavy chain (V_H) and light chain (V_L) genes of anti-CD20 monoclonal antibody HI⁴⁷ were cloned from anti-CD20 ScFv expression vector pCANBTEcd20 by PCR and ligated into vector pYZF to construct chimeric anti-CD20 Fab’ fragment expression vector pYZFcd20. Chimeric anti-CD20 Fab’ fragment was expressed inE. coli 16C9 and purified by protein G affinity chromatography. Competitive inhibition assay showed that anti-CD20 Fab’ fragment inhibited binding of HI⁴⁷ to CD20 on the surface of Daudi cells. Results from MTT assay indicated that chimeric anti-CD20 Fab’ fragment inhibited the proliferation of Daudi cells, IC₅₀ = 69 μg/mL. Affinity of chimeric anti-CD20 Fab’ fragment was determined, K_a was about 8.9×10⁸ (mol/L)⁻¹.     

Contemporary crustal movement of continental China obtained by global positioning system (GPS) measurements

We obtain a unified horizontal velocity field of continental China and vicinity through measurements at 81 GPS stations provided by the National Key Infrastructure Project, Crustal Movement Observation Network of China. The velocity field delineates patterns of movements and deformation of active crustal blocks in continental China under the Eurasia-fixed reference frame. The space-based geodesy also clearly shows for the first time the horizontal movement and deformation of continental China induced by indentation of the Indian plate. The data provide kinematic constraints for simulating dynamic process of continental lithospheric deformation.     

定距引信的电子计转数方法

根据旋转弹丸在外弹道上的运动 ,推导出了引信零件在弹道上的运动角速度和离心加速度表达式 ,通过计算和模拟仿真得到了脉动的离心加速度曲线 ,在引信动态模拟装置上进行模拟测试 ,验证了理论分析的正确性 ,提出了通过直接计弹丸转数实现引信定距功能的方法。