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221.
采用X-射线衍射仪(XRD)、扫描电子显微镜(SEM)、电池性能测试仪等系统分析了Pechini法合成的LiMxMn2-xO4(M=La,Ce,Nd;x=0,0.02,0.03)的结构、形貌、首次充放电及循环稳定性等.结果表明;除LiCe0.03Mn1.97O4、LiNd0.03Mn1.97O4样品含有微量杂质相(CeO2或Nd2O3)外,其他样品均具有纯的尖晶石型LiMn2O4结构;样品呈规则的球形或近球形,粒径为1.0~2.0μm;采用适量的稀土掺杂可显著提高LiMn2O4样品的首次充放电和循环稳定性能,LiLa0.02Mn1.97O4样品的首次放电容量为123.3 mAh/g,经30次循环充放电后的容量仍保持在112.8 mAh/g,容量保持率为91.5%,远高于相同条件下未掺杂样品的容量保持率.  相似文献   
222.
强震作用下钢-混凝土结构弹塑性损伤分析   总被引:2,自引:0,他引:2  
通过LS-DYNA程序二次开发了钢材的弹塑性损伤本构模型,并分别建立了钢框架和混凝土核心筒的损伤准则.对强震作用下某20层的钢-混凝土混合结构的层间位移、框架与核心筒之间剪力分配等进行了数值分析,结果表明混凝土核心筒变形能力较钢框架差,强震作用下容易在薄弱层处产生变形集中破坏;对两种结构体系损伤发展过程分析表明,损伤指数能很好地跟踪两种结构体系的抗震能力退化过程,该模型和损伤准则可以用于强震作用下钢-混凝土混合结构的弹塑性损伤分析.  相似文献   
223.
Amplification of a gene coding for human T-cell differentiation antigen   总被引:1,自引:0,他引:1  
P Kavathas  L A Herzenberg 《Nature》1983,306(5941):385-387
Using previously isolated mouse L-cell transferents for the human T-cell differentiation antigen Leu-2, we now report the first example of spontaneous gene amplification for membrane antigens. The Leu-2 (or T8) antigen is normally expressed on T lymphocytes that have cytotoxic or suppressor functions. Cells of a Leu-2 transfected clone were stained with fluorescein-tagged monoclonal anti-Leu-2, and the brightest 0.1-0.3% of cells were viably separated using a fluorescence activated cell sorter (FACS). After growth of these selected cells, sorting and regrowth was repeated six times, resulting in a population of cells that, compared with the starting population, stains 40 times brighter for Leu-2 and whose DNA transforms 20 times more efficiently for Leu-2. In addition, these cells have 10- to 50-fold amplified human DNA sequences and numerous double minute chromosome fragments, a common indicator of gene amplication in mouse cells.  相似文献   
224.
N-cadherin is related to the progression and metastases of several solid carcinomas. However, it was still unclear whether N-cadherin is overexpressed in colorectal malignant tumors that have stronger malignant tendency. In this study, we used immunohistochemistry to detect the expression patterns of N-cadherin in both the primary tumors and their normal mucosa tissues of 120 patients with colorectal cancer. We revealed that N-cadherin was expressed in 78.3% (94/120) of colorectal tumor tissues and in only 9.2% (11/120) of paired distant normal mucosa tissues with a significant difference (P=0.000). The low, moderate, and high expression of N-cadherin protein was 42.5%, 30.8%, and 26.7%, respectively. N-cadherin overexpression was associated with advanced TNM stage, lymph nodes metastasis and distant metastasis (P<0.05). Patients with N-cadherin overexpressed showed the obvious lower overall survival rate than those with moderate and low expression, and patients with low expression had a better survival rate than those with moderate and high expression (P<0.05). In conclusion, high N-cadherin expression may lead to tumor aggressiveness and metastatic potential in colorectal cancer, and may prove to be a possible prognostic factor.  相似文献   
225.
基于双极性多脉冲的UWB调制方案及性能分析   总被引:1,自引:0,他引:1  
针对普遍单脉冲位置调制的不足,在已有的UWB(Ultra-Wideband)脉冲位置调制研究基础上,提出了一种改进的双极性多脉冲位置调制(AMPPM:Ambipolar Multi-Pulse Position Modulation)的UWB跳时调制方案,并对其加性高斯白噪声(AWGN:Additive white Gaussian Noise)下的信道容量,最大可靠通信距离等性能指标进行了理论分析。理论分析及实验数值结果表明,在相同的条件下,与普通的单脉冲位置调制(PPM:Pulse Position Modulation)相比,AMPPM能获得较高的容量,即在给定可实现脉冲宽度下可获得更高的通信速率。仿真结果表明,当脉冲宽度为0.5 ns时,L进制AMPPM可达到333 Mbit/s的速率,而同等条件下的L进制PPM仅能达到167 Mbit/s的速率。同时AMPPM在最大可靠通信距离指标方面也较相应的PPM及脉冲幅度调制(PAM:Pulse Amplitude Modulation)有改善,在100 Mbit/s及10-4的误码率下可达到8 m的通信距离。  相似文献   
226.
论述了目前的软件开发中存在的两个问题:①现有的高级语言对各种高级计算模型支持的不足;②快速原型开发和高质量产品开发之间的矛盾,针对上问题,设计了一种新的面向对象语言Transframe并研制了它的开发环境MagicFrame.Transframe语言具有的参数化的动态类、名的一般模型、类与函数概念的统一、成员类继承和代理等多种机制为构造各种领域模型提供了有力的支持。基于Transframe的开发环  相似文献   
227.
The demography of a population of Yarrow's spiny lizard, Sceloporus jarrovii , was examined from 2004 to 2006 in the canyon Las Piedras Encimadas, located in Gomez Palacio, Durango, México. Lizards were studied using a mark-recapture technique. Reproduction in females occurred between November and May, coinciding with dry conditions. Reproductive activity was highest (percent of females with vitellogenic follicles or embryos) in the middle of the dry season (November and December). Thirteen percent of females reached sexual maturity at an average age of 8.5 months. The population structure was similar in spring and fall, but not in summer. A notable feature of summer, coinciding with the wet season, was the greater number of hatchlings and juveniles. The overall sex ratio did not differ from 1:1. The density of adults varied from 12 to 62 animals ? 0.5 ha –1 . Temperate and arid-adapted populations of S. jarrovii exhibited broad similarity in timing of the reproductive season, whereas factors such as density, growth, age at sexual maturity, and survivorship differed.  相似文献   
228.
We measured predation on 120 artificial Sage Grouse ( Centrarcus urophasianus ) nests in montane sagebrush grassland in northern Utah. We examined nests in areas that had been chained and seeded 25 years previously (treated areas) and in areas that were untreated. Predation rates of artificial nests were higher in areas of untreated sagebrush, even though these areas had greater sagebrush cover, taller shrubs, and greater horizontal plant cover. These results differ from those previously hypothesized for treated sagebrush habitat and may reflect a greater abundance of other potential prey species, especially lagomorphs, in untreated areas that attracted greater densities of predators. In addition, over 80% of nests were depredated by mammals, which hunt using olfaction and are less likely than avian predators to be affected by nest cover. We conclude that, after treated sagebrush has recovered to some degree, predation rates of Sage Grouse nests may be lower in treated sagebrush. Consequently, factors other than nest predation (e.g., winter food, thermal cover, insects, perennial forb abundance) may be more important reasons for preserving mature sagebrush stands for Sage Grouse.  相似文献   
229.
Gene mutations in invertebrates have been identified that extend life span and enhance resistance to environmental stresses such as ultraviolet light or reactive oxygen species. In mammals, the mechanisms that regulate stress response are poorly understood and no genes are known to increase individual life span. Here we report that targeted mutation of the mouse p66shc gene induces stress resistance and prolongs life span. p66shc is a splice variant of p52shc/p46shc (ref. 2), a cytoplasmic signal transducer involved in the transmission of mitogenic signals from activated receptors to Ras. We show that: (1) p66shc is serine phosphorylated upon treatment with hydrogen peroxide (H2O2) or irradiation with ultraviolet light; (2) ablation of p66shc enhances cellular resistance to apoptosis induced by H2O2 or ultraviolet light; (3) a serine-phosphorylation defective mutant of p66shc cannot restore the normal stress response in p66shc-/- cells; (4) the p53 and p21 stress response is impaired in p66shc-/- cells; (5) p66shc-/- mice have increased resistance to paraquat and a 30% increase in life span. We propose that p66shc is part of a signal transduction pathway that regulates stress apoptotic responses and life span in mammals.  相似文献   
230.
In the fast evolving field of nanoscience and nanotechnology,where size and shape are crucial in deciding the optoelectronic properties of nanomaterials,the understanding of size and shape dependent behavior is of direct relevance to device applications.Present study reports the synthesis of Au nanorods with well controlled aspect ratios,and the influence of the aspect ratio on the surface enhanced Raman scattering(SERS) activity using crystal violet(CV) as the probe molecule.The influence of pH and the concentrations of reducing agent and Ag ions in controlling the aspect ratio of gold nanorods are also investigated.The structural and optical properties of the synthesized samples have been characterized by transmission electron microscopy(TEM) and UV-visible absorption spectroscopy.The nonlinear optical(NLO) transmission of the Au nanorods investigated using the open aperture Z-scan technique revealed the absorption saturation followed by an optical limiting behavior,which may find potential applications in optoelectronic nanodevices.  相似文献   
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