步行机相交面运动规划

针对步行机的一般结构特征,提出一种步行机在任意夹角相交面上的运动规划,对其在各种不同情况下的相应运动过程分别进行了分析。根据步行机车体姿态调整能力,以最大调整姿态角和最少相交面落足点变化为优化目标,建立了运动模型,同时确定出最佳初始状态。最后,对几种典型的相交面运动进行了仿真和实验,结果表明,步行机能够成功地实现在不同夹角相交面上的运动。应用该运动规划和优化算法,可以充分发挥步行机灵活的运动能力,大大简化其在相交面上的运动过程。     

隐式单索夹持式玻璃幕墙承载性能的试验

为研究预应力、玻璃刚度、耐候胶及套管对隐式单索夹持式玻璃幕墙承载性能的影响,进行了试验研究。并在各级预应力以及安装玻璃后施加平面外荷载的条件下研究体系的承载性能,同时进行测试来比较打胶及设置套管前后的承载性能差异。此外,还获取了预应力、玻璃刚度及荷载条件下体系的自振频率。试验结果表明:平面外荷载越大,增加钢索预应力对降低体系变形的作用越小;玻璃自重对体系的自振频率影响远大于刚度的影响;耐候胶及套管对承载性能的影响较小。     

Molecular mechanism for distinct neurological phenotypes conveyed by allelic truncating mutations

The molecular mechanisms by which different mutations in the same gene can result in distinct disease phenotypes remain largely unknown. Truncating mutations of SOX10 cause either a complex neurocristopathy designated PCWH or a more restricted phenotype known as Waardenburg-Shah syndrome (WS4; OMIM 277580). Here we report that although all nonsense and frameshift mutations that cause premature termination of translation generate truncated SOX10 proteins with potent dominant-negative activity, the more severe disease phenotype, PCWH, is realized only when the mutant mRNAs escape the nonsense-mediated decay (NMD) pathway. We observe similar results for truncating mutations of MPZ that convey distinct myelinopathies. Our experiments show that triggering NMD and escaping NMD may cause distinct neurological phenotypes.     

城市声景观表述方法的研究

提出了声景观图的概念，用来作为城市声景观的表述方法．声景观图由客观信息、主观信息、关系分析以及模拟信息等组成．同时，文中还提出了开发声景观图的方法，包括信息收集、数据处理、制图、分析和模拟等过程．然后以日本佐贺市作为案例制作和分析了该区域的声景观图．最后分析了声景观图的应用方法和前景．文中提出的声景观图是表述和分析城市声景观的有效方法．     

Decision Research Using Cognitive Structures

This paper describes a form of management epistemology, and suggests that it be called Decision Research, since it is primarily based on what can be learned from how managers make decisions in practice. The paper proposes that Decision Research be founded on generic cognitive structures that show a high degree of stability from east to west, old to new. These are described by Nomology, the science of the laws of the mind, and so have a positivist flavor. The paper develops, through an understanding of settled practice, how these structures are used in different cultures and fields of management. The richness of diversity it reveals encourages an interpretivist approach. Its value to Systemic Practice comes from the way that it provides frameworks and maps to elucidate issues and resolve situations in management.     

The effect of vasoactive agents on nutritive collateral circulation in rat muscles

Summary The relationship between the collateral and control nutritive blood flow (⁸⁶Rb) of the triceps muscle was not influenced by vasoactive agents (phenylephrine, angiotensin II, vasopressin) in the rat. Isolevine caused vasodilation only in the control muscle.