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851.
Tian Dong 《系统科学与复杂性》2016,29(5):1382-1399
Farr-Gao algorithm is a state-of-the-art algorithm for reduced Gröbner bases of vanishing ideals of finite points, which has been implemented in Maple as a build-in command. This paper presents a two-dimensional improvement for it that employs a preprocessing strategy for computing reduced Gröbner bases associated with tower subsets of given point sets. Experimental results show that the preprocessed Farr-Gao algorithm is more efficient than the classical one. 相似文献
852.
This paper considers an on-line scheduling and routing problem concerning the automated storage and retrieval system from tobacco industry. In this problem, stacker cranes run on one common rail between two racks. Multiple input/output-points are located at the bottom of the racks. The stacker cranes transport bins between the input/output-points and cells on the racks to complete requests generated over time. Each request should be accomplished within its response time. The objective is to minimize the time by which all the generated requests are completed. Under a given physical layout, the authors study the complexity of the problem and design on-line algorithms for both one-stacker-crane model and two-stacker-crane model. The algorithms are validated by instances and numerical simulations. 相似文献
853.
854.
Jutta Steinberger Jennifer Chu Rayelle Itoua Maïga Katia Sleiman Jerry Pelletier 《Cellular and molecular life sciences : CMLS》2017,74(9):1681-1692
Biotherapeutics have revolutionized modern medicine by providing medicines that would not have been possible with small molecules. With respect to cancer therapies, this represents the current sector of the pharmaceutical industry having the largest therapeutic impact, as exemplified by the development of recombinant antibodies and cell-based therapies. In cancer, one of the most common regulatory alterations is the perturbation of translational control. Among these, changes in eukaryotic initiation factor 4F (eIF4F) are associated with tumor initiation, progression, and drug resistance in a number of settings. This, coupled with the fact that systemic suppression of eIF4F appears well tolerated, indicates that therapeutic agents targeting eIF4F hold much therapeutic potential. Here, we discuss opportunities offered by biologicals for this purpose. 相似文献
855.
通过全面研读2012农事年美国农业保险手册,总结美国农业保险实务操作,结合我国农业保险现状,主要有以下启示:1)重视历史数据,实际产量历史数据库是农业保险的基础;2)重视可操作性,保险规章要求事无巨细,详尽规范;3)农业保险合同中的土地投保单元设置多样化. 相似文献
856.
反思是服务学习的一个重要特质,也是实施过程中一个重要的阶段,是保证服务学习质量,提升服务效果的重要组成部分。本文主要从反思的理论基础,反思的特质以及反思的作用等方面阐述反思在服务学习中的地位和价值,有助于更好地开展服务学习,提升服务学习效果。 相似文献
857.
程薇 《西安联合大学学报》2016,(4):103-106
中国特色社会主义民主通过科学的规制和有序的实践,确立人民群众的历史活动主体和价值主体的地位,彰显以人为本的生态实然。"十三五"时期中国特色社会主义民主发展面临着腐败、贫富差距、制度外政治参与、借鉴西方民主等现实难题。"十三五"时期,以科学发展观为统帅,结合"四个全面"战略布局,从民主制度与民主生活的有机互动中把握中国特色社会主义民主发展的内在逻辑,构建其科学发展的现实路径。 相似文献
858.
Cornelia Ringer Sarah Tune Mirjam A Bertoune Hans Schwarzbach Kazutake Tsujikawa Eberhard Weihe Burkhard Schütz 《Cellular and molecular life sciences : CMLS》2017,74(2):339-358
Amyotrophic lateral sclerosis (ALS) is a fatal motor neuron disease. Neuronal vacuolization and glial activation are pathologic hallmarks in the superoxide dismutase 1 (SOD1) mouse model of ALS. Previously, we found the neuropeptide calcitonin gene-related peptide (CGRP) associated with vacuolization and astrogliosis in the spinal cord of these mice. We now show that CGRP abundance positively correlated with the severity of astrogliosis, but not vacuolization, in several motor and non-motor areas throughout the brain. SOD1 mice harboring a genetic depletion of the βCGRP isoform showed reduced CGRP immunoreactivity associated with vacuolization, while motor functions, body weight, survival, and astrogliosis were not altered. When CGRP signaling was completely disrupted through genetic depletion of the CGRP receptor component, receptor activity-modifying protein 1 (RAMP1), hind limb muscle denervation, and loss of muscle performance were accelerated, while body weight and survival were not affected. Dampened neuroinflammation, i.e., reduced levels of astrogliosis in the brain stem already in the pre-symptomatic disease stage, and reduced microgliosis and lymphocyte infiltrations during the late disease phase were additional neuropathology features in these mice. On the molecular level, mRNA expression levels of brain-derived neurotrophic factor (BDNF) and those of the anti-inflammatory cytokine interleukin 6 (IL-6) were elevated, while those of several pro-inflammatory cytokines found reduced in the brain stem of RAMP1-deficient SOD1 mice at disease end stage. Our results thus identify an important, possibly dual role of CGRP in ALS pathogenesis. 相似文献
859.
将M-估计稳健损失函数与基于统计贡献度的动态确定核函数方法相结合, 提出一种有效的非参数RBF预测模型, 该方法克服了稳健性缺失问题, 在估计参数的同时动态确定最佳网络结构, 并且在学习中自动消除噪声和异常点的影响, 加快了网络的学习和收敛速度. 利用中国月度信贷数据进行实证分析表明, 本文模型与基准模型相比具有最好的预测稳健性和准确性, 对于提高货币政策有效性和前瞻性具有很好的应用价值. 相似文献
860.
基于传统的多用户差分混沌移位键控(differential chaos shift keying,DCSK),本文提出一种新型的多进制多用户DCSK 混沌扩频通信方案。该方案在发送端将二进制码元转换为多进制码元,极大提高了二进制码元的传输速率,并利用频分复用实现多用户传输。接收端将所有用户参考信号合并作为新的参考信号,分别与各个用户进行相关解调。仿真结果表明,增加用户数可以有效改善多进制多用户DCSK系统的误码性能,该方案具有一定的实际应用价值。 相似文献