贝叶斯规整化神经网络预测苯取代物的毒性

利用贝叶斯规整化神经网络(BRNN)研究了59种苯取代的环境毒性和分子结构的关系.建立了基于脂水分配系数和4种量子指数的QSAR环境毒性预测模型.结果表明:该模型的预测性能超过偏最小二乘法(PLS)和逐步线性回归方法,残差分析显示其稳定可靠,有望成为一种良好的苯取代物毒性的环境评价和预测的方法.     

The c-myc coding DNA sequences of cyprinids （Teleostei： Cypriniformes）： Implications for phylogeny

The family Cyprinidae is one of the largest fish families in the world, which is widely distributed in East Asian, with obvious difference in characteristic size among species. The phylogeneUc analysis of cyprinid taxa based on the functionally important genes can help to understand the speciation and functional divergence of the Cyprinidae. The c-myc gene is an important gene regulating individual growth. In the present study, the sequence variations of the cyprinid c-myc gene and their phylogenetic significance were analyzed. The 41 complete sequences of the c-myc gene were obtained from cyprinids and outgroups through PCR amplification and clone. The coding DNA sequences of the c-myc gene were used to infer molecular phylogenetic relationships within the Cyprinidae. Myxocyprinus asiaticus （Catostomidae）, Misgurnus anguillicaudatus （CobiUdae） and Hemimyzon sinensis （Homalopteridae） were assigned to the outgroup taxa. Phylogenetic analyses using maximum parsimony （MP）, maximum likelihood （ML）, and Bayesian retrieved similar topology. Within the Cyprinidae, Leuciscini and Barbini formed the monophyletic lineage respectively with high nodal supports. Leuciscini comprises Xenocyprinae, CuItrinae, East Asian species of Leuciscinae and Danioninae, Gobioninae and Acheilognathinae, and Barbini contains Schizothoracinae, Barbinae, Cyprininae and Labeoninae. Danio rerio, D. myersi and Rasbora trilineata were supposed to separate from Leuciscinae and Barbini and to form another lineage. The positions of some Danioninae species were still unresolved. Analyses of both amino acid variation with parsimony information and two high variation regions indicated that there is no correlation between variations of single amino acid or high variation regions and characteristic size of cyprinids. In addition, the species with smaller size were usually found to be basal within clades in the tree, which might be the results of the adaptation to the primitive ecology and survival pressure.     

孤独症儿童治疗方法概况

自1943年以来,经过半个多世纪的时间,关于孤独症的理论与治疗技术日趋成熟。本文对一些主要治疗方法与技术进行了简要回顾,着重介绍了近年来在美国有广泛应用的RDI疗法。针对我国孤独症教育治疗不足的现状对治疗过程中的问题进行了一定归纳。     

机械产品功能建模及其求解策略的研究

简要阐述用于产品功能建模的标准功能基(SFB),并在SFB基础上完成产品功能建模;建立包括元功能层、功能对象层、行为层、结构组件层和结构关系层的功能求解模型,提出多层次柔性求解策略用于完成从功能到结构的映射;以实例对所提出的方法进行验证。     

内配煤团块直接还原法制备铁粒技术研究

根据我国现阶段直接还原状况及国内能源的结构特点，提出利用舍碳团块直接还原制备铁颗粒的技术思想；通过调整团矿的内配碳比、温度、碱度及添加剂配入量来优化渣铁的分离和提高铁粒质量，找到最佳的配比方案。铁的收得率达到90％以上，铁粒中wFe〉96％，ws=0．02％～0．05％，wc〈4．0％；分离出的铁粒可直接作为电炉炼钢的优质原料。     

支持向量机在电力变压器故障诊断中的应用

利用支持向量机的学习方法，构建了电力变压器故障诊断模型．该模型将变压器故障分为放电性和过热性两大类，通过统计分析寻求特征量区分类间的故障类型，采用支持向量机识别类内的故障类型，利用基于交叉验证的网格搜索法来确定支持向量机的参数．考虑到变压器油中溶解气体特征空间的紧致性原理，利用模糊C均值聚类算法对所获取的样本进行预选取，有效地解决了确定模型参数时耗时巨大的问题，并一定程度提高了模型的推广能力．实例验证表明，该模型在有限样本情况下，能达到较高的变压器故障判断率，放电性故障样本正确判断率为90．5％，过热性故障样本正确判断率为85．9％，说明该模型具有很好的分类效果和推广能力．     

浅析伊通河地表水中镉迁移转化的规律

通过近4a对伊通河长春段6个地表水监测断面中重金属镉的研究，结果表明，地表水中镉的含量随流程的增加而增加，年平均含量也在递增。此外，研究区域内，镉以Cd^2＋为主，且镉有接近超标并逐年升高的趋势。     

高师院校继续教育现状及发展策略浅析

继续教育是当今教育先于经济发展的一个教育变革的突出标志,是构建终身教育体系和建立学习型社会的重要途径,是实现高等教育大众化、提高全民文化知识水平的有效手段。当前,高师院校继续教育的发展面临着地位低下、管理体制不健全、缺乏政策支持、教学手段和方法落后、管理松懈效率不高、教学质量得不到保证等诸多问题,本文拟针对这些问题提出解决的办法和发展策略,以促进高师院校继续教育的可持续发展。     

High variability of the gvpA-gvpC region in Microcystis

Gas vesicles provide buoyancy to Microcystis and other common cyanobacterial bloom-forming species. gvpA and gvpC are structural genes encoding gas vesicle proteins. Phylogenetic analyses of 10 Microcystis strains/uncultured samples showed that gvpC and each intergenic segment of the gvpA-gvpC region can be divided into two types. The combination of different types of gvpC and intergenic segments is an important factor that diversifies this genomic region. Some Microcystis strains isolated in China possess a 172 to 176 bp sequence tag in the intergenic segment between gvpA and gvpC. The gvpA-gvpC region in Microcystis can be divided into at least 4 classes and more numbers of subclasses. Compared to rbcLX and other regions, the high variability of the gvpA-gvpC region should be more useful in identifying geographical isolates or ecotypes of Microcystis.     

热轧带钢横向温度研究方法及测量分析

对目前带钢横向温度分布的研究方法和结论进行了分析;对1800热连轧机精轧出口带钢的横向温度进行测量,针对典型的分布规律,提出了描述参数,并用该参数就其分布规律以及分布与带钢宽度、纵向温度的关系进行了讨论,为建立热连轧带钢横向温度控制模型提供了依据.