棉花种子变温冷害的初步研究

以棉花种子新陆早１号为材料，研究了２０～１２℃、２０～８℃、２０～２℃、１６～８℃、１６～２℃、１２～５℃六种不同变温分别处理１天、２天、３天、４天、５天后的发芽率，初步认清了棉花种子变温与冷害的关系．结果表明，变温的幅度及低温的程度是决定冷害的主要因素，低变温的持续时间也是影响冷害的主要因素．     

磁水对玉米幼苗生理生化效应的初步研究

用不同磁场强度（０．０５Ｔ、０．１０Ｔ和０．１５Ｔ）的磁水处理玉米种子、幼苗，发现一定磁场强度的磁水能提高叶片中叶绿素含量、硝酸还原酶（ＮＲ）活性，但降低ＩＡＡ氧化酶活性、呼吸速度和电导率．结果表明：磁水具有增强玉米幼苗进行光合作用、氮代谢和抑制ＩＡＡ降解、提高其抗冻性的效应．     

塑性变形和热处理工艺对白口铸铁组织及性能的改善

大于2.11％C的白口铸铁中含有大块且又分布不均匀的渗碳体,其塑性和韧性很差。本文采用塑性变形及热处理等4种方法,最终得到了细小碳化物均匀分布在铁素体基体上的理想组织。具有这种球化组织的铸铁,强韧性有了提高,且在650～850℃温度范围变形表现出良好的超塑特性。     

高校法制教育与心理教育整合研究

研究高校法制教育与心理教育的整合,主要目的是将两种教育融会贯通,真正达到教育大学生,指引他们形成正确的价值观、人生观以及世界观的目标。可从教材整合、授课内容丰富、专业师资力量培养、利用现代教学设备方面来整合心理教育与法律教育。     

1-(2′-硫代乙酸)-3-甲基-4-丁基-5-羟基嘧啶及其稀土配合物的合成和其抗菌活性

本文用1-巯基-3-甲基-4-丁基-5羟基嘧啶(HSQ)与α-氯乙酸反应合成了新的配体1-(2′-硫代乙酸)-3-甲基-4-丁基-5-羟基嘧啶(HL);又用该配体与氯化稀土反应制得了4种稀土配合物.通过元素与化学分析,IR,UV,~1HNMR,摩尔电导,热分析等对配合物的结构和性质进行了表征.测试了配合物的抗菌活性.结果表明,配合物浓度在200～50mg/L 时,有一定抗菌活性.     

Variation in FTO contributes to childhood obesity and severe adult obesity

We identified a set of SNPs in the first intron of the FTO (fat mass and obesity associated) gene on chromosome 16q12.2 that is consistently strongly associated with early-onset and severe obesity in both adults and children of European ancestry with an experiment-wise P value of 1.67 x 10(-26) in 2,900 affected individuals and 5,100 controls. The at-risk haplotype yields a proportion of attributable risk of 22% for common obesity. We conclude that FTO contributes to human obesity and hence may be a target for subsequent functional analyses.     

Systematic pathway analysis using high-resolution fitness profiling of combinatorial gene deletions

Systematic genetic interaction studies have illuminated many cellular processes. Here we quantitatively examine genetic interactions among 26 Saccharomyces cerevisiae genes conferring resistance to the DNA-damaging agent methyl methanesulfonate (MMS), as determined by chemogenomic fitness profiling of pooled deletion strains. We constructed 650 double-deletion strains, corresponding to all pairings of these 26 deletions. The fitness of single- and double-deletion strains were measured in the presence and absence of MMS. Genetic interactions were defined by combining principles from both statistical and classical genetics. The resulting network predicts that the Mph1 helicase has a role in resolving homologous recombination-derived DNA intermediates that is similar to (but distinct from) that of the Sgs1 helicase. Our results emphasize the utility of small molecules and multifactorial deletion mutants in uncovering functional relationships and pathway order.