Histamine as an extremely potent releaser of vasopressin in the rat

Summary Intraperitoneal and intraventricular injection of histamine induces a very fast and high elevation of vasopressin in rat plasma as determined by radioimmunoassay. The effects are dose and time related. The intraventricular injection is more effective with regard to time and dose than the intraperitoneal injection.     

Spontaneous deoxygenation of N-(3,4-methylenedioxybenzyl)-acetohydroxamic Acid: An exceptionally facile process

Summary An exceptionally facile spontaneous deoxygenation of N-(3,4-methylenedioxybenzyl)-acetohydroxamic acid to its corresponding amide, without apparent literature precedent, is reported.We acknowledge the Research Corporation for financial support.     

Seasonal monoamine changes in the central nervous system ofMytilus edulis (Bivalvia)

Summary The levels of serotonin, dopamine and norepinephrine exhibit seasonal changes in the central nervous system of Mytilus edulis. These monoamines were higher during the summer and lower during the winter.     

Raffinose as reserve sugar inDysdercus koenigii—a biosynthesis confirmation by14C glucose

Summary Dysdercus koenigii, studied for its sugar spectrum, showed consistent absence of trehalose in its blood and body muscles. Instead of this known reserve sugar, raffinose has been shown to fulfil this need. The biosynthesis confirmation has been made by¹⁴C glucose.     

Mass fragmentographic determination of cholecalciferol and 25-hydroxycholecalciferol in human serum

Summary The serum extracts were purified by column-, thin layer- and high pressure liquid chromatography. Deuterated cholecalciferol and deuterated 25-hydroxycholecalciferol were used as internal standards. The quantitative analysis was performed using GC-mass fragmentography technique of TMS-ethers.     

Nuclear lamellae in the germ-line cells of gall midges (Cecidomyiidae,Diptera)

Summary Lamellar structures in oogonial and spermatogonial cells of gall midges were found to form a complicated system of intranuclear compartments inside which all heteropycnotic chromosomes present in the germ-line cells of these insects are located. In this way, the heteropycnotic S-chromosomes are separated by the nuclear lamellae from the remaining, decondensed chromosomes (E-chromosomes) of the interphase germ-line nucleus.This investigation was supported in part under Contract DPKBN/52/76-II.1.3.10. with the Polish Academy of Sciences.     

Renin in mouse but not in rat submandibular glands

Renin was found in the submandibular glands of male Quackenbush mice in concentrations higher than has been reported for any tissue of any strain or species. However, no renin-like activity could e detected in glands from male and female Wistar rats using either pH 5.8 or 7.4 for assay and a radioimmunoassay specific for renin's reaction product, angiotensin I. Rabbit submandibular glands contained renin.     

1,2-di-n-butylhydrazine dihydrochloride carcinogenesis in mice

Summary A solution of 0.0625% 1,2-di-n-butylhydrazine dihydrochloride (1,2-DBH) was given continuously in the drinking water of 6-week-old randomly bred albino Swiss mice for the remainder of their lives. The treatment gave rise to tumors of the lungs, lymphoreticular tissue and kidneys.