Vanadyl ions binding to GroEL （HSP60） and inducing its depolymerization

Several vanadium compounds have been known for the hypoglycemic and anticancer effects. However, the mechanisms of the pharmacological and toxicological effects were not clear. In this work, we in- vestigated the potential targets of vanadium in mitochondria. Vanadyl ions were found to bind to mi- tochondria from rat liver with a stoichiometry of 244±58 nmol/mg protein and an apparent dissocia- tion constant (Kd) of (2.0±0.8)×10·16 mol/L. Using size exclusion chromatography, a vanadium-binding protein was isolated and identified to be the 60-kDa heat shock protein (HSP60) by mass spectrometry analysis and immunoassays. Additionally, binding of vanadyl ions was found to result in depolymeri- zation of homo-oligomeric HSP60 (GroEL). HSP60 is an indispensable molecular chaperone and in- volved in many kinds of pathogenesis of inflammatory and autoimmune diseases, e.g. type 1 diabetes. Our results suggested that HSP60 could be a novel important target involved in the biological and/or toxicological effects of vanadium compounds.     

基于CUDA的图形处理器FDTD算法仿真研究

由于数值色散及时域迭代的特点,利用时域有限差分（FDTD）进行电磁仿真往往是十分耗时的,通用图形处理器（GPGPU）技术为其提供了解决方案。通过分析FDTD算法及其数值稳定条件,阐明其天然并行优势。基于计算统一设备架构（CUDA）模型,提出了利用图形处理器并行FDTD仿真的实现方法,并与传统CPU计算相比较,验证了并行结果的精确性,分析了各种尺度网格下速度提升情况,通过进一步优化并行方法,计算速度与单CPU相比可提升数十倍。     

基于XGBoost预测及弹性网误差补偿的室内定位算法

为解决室内定位系统中因环境动态变化而导致定位精度下降的问题,提出一种基于XGBoost并融合弹性网的误差补偿算法。采用XGBoost定位模型对目标位置进行初步预测,当室内环境改变后,再采用弹性网算法构建误差补偿模型,修正XGBoost定位模型的定位误差,并与基于K近邻、支持向量机、随机森林、梯度提升决策树等定位算法做对比。实验结果表明：在更新15%指纹数据库样本的情况下,该算法在80%分位处的定位精度控制在0.73 m以内,明显优于其他定位算法,且较基于XGBoost的定位算法精度提高了25.5%。     

群体性突发事件的演化博弈分析——以辽东湾海蜇捕捞为例

运用演化博弈分析方法．建立辽东湾违规捕捞海蜇群体性突发事件的演变模型．通过模型分析辽东湾违规捕捞海蜇群体性突发事件发生、发展的原因及演变规律。提出杜绝此类事件的政策建议，探讨如何建立长期有效的辽东湾海蜇捕捞制度。谊模型可以推广到一般的群体性突发事件．对研究群体性突发事件具有一定的借鉴意义。     

A novel method for improving cerussite sulfidization

Evaluation of flotation behavior, solution measurements, and surface analyses were performed to investigate the effects of chloride ion addition on the sulfidization of cerussite in this study. Micro-flotation tests indicate that the addition of chloride ions prior to sulfidization can significantly increase the flotation recovery of cerussite, which is attributed to the formation of more lead sulfide species on the mineral surface. Solution measurement results suggest that the addition of chloride ions prior to sulfidization induces the transformation of more sulfide ions from pulp solution onto the mineral surface by the formation of more lead sulfide species. X-ray diffraction and energy-dispersive spectroscopy indicate that more lead sulfide species form on the mineral surface when chloride ions are added prior to sulfidization. These results demonstrate that the addition of chloride ions prior to sulfidization can significantly improve the sulfidization of cerussite, thereby enhancing the flotation performance.     

Application of the modified neighborhood interference model to the cultivation of forest and herbaceous ecosystem

This paper is an extension of the application of neighborhood interference model--being modified--to the study of the interference between forest plants and herbaceous plants. The exploration of the neighborhood interference between triploid Populus tomentosa and Lolium multiflorum shows that the interference of Lolium multiflorum on triploid populus tomentosa is positive, with the primary interference factor living weight, and secondary factor cover degree; the growth of an individual tree is affected by the number, height, and coverage of the Lolium multiflorum; the more dense the coverage of the Lolium multiflorum in a certain area, the taller, faster and more trees will grow as a result of a greater positive neighborhood interference. The modified neighborhood interference model well serves as an effective approach to extend the application of neighborhood interference researches.     

CoCu析氧纳米合金制备及性能调控机理

采用电化学沉积法制备了一种多边形结构的Co Cu二元合金纳米颗粒,研究了其析氧性能及调控机理.SEM和XRD表征结果表明,该材料在电沉积过程中合金化程度较高且Co和Cu之间的合金化作用明显.组分调控结果表明,Co含量与析氧活性的作用呈非线性规律,70%的Co含量为最佳配比.在0.1 mol/L KOH溶液中,Co₇Cu₃二元合金纳米催化剂具有极高的析氧活性,其析氧过电位为379.5 mV,Tafel斜率为278 mV/dec,活性电流密度高达55.6 A/g.同时,在0.8 V_SCE的恒定电位下,该催化剂稳定持续工作40000 s后,其活性衰减率为10%,表明该催化剂具有较好的电化学稳定性.     

Synthesis of BiOCl photocatalyst by a low-cost,simple hydrolytic technique and its excellent photocatalytic activity

A novel photocatalyst, bismuth oxychloride (BiOCl) micro-nano particles with a fine ferrite plate structure, was prepared by a low-cost, simple hydrolytic method. The as-prepared BiOCl was characterized by scanning electron microscopy (SEM), thermogravimetric analysis-differential thermal analysis (TGA-DTA), X-ray diffraction (XRD), and UV-vis diffuse reflectance spectra (DRS). The effects of preparation conditions such as sodium dodecyl benzene sulfonate (SDBS) dispersant, HCl concentration, and heat treatment temperature on BiOCl performances were investigated. Moreover, its photocatalytic activity was evaluated on the degradation of methylene orange (MO) and was compared with that of TiO₂ (P25). The experimental results confirmed that BiOCl micro-nano particles prepared with SDBS, the HCl concentration of 1.5 mol/L, and the heat treatment temperature of 80℃ exhibited the best performance for the photodegradation of MO solution, and they showed good stability and better photocatalytic activity than P25 photocatalyst.     

Research on Computing Models of CBR Similarity

Several models of measuring case similarity in CBR systems are deeply explored. We also discuss the case matching process, and present three matching functions. Finally, we illustrate the significance of the models in CBR(Case Based Reasoning) systems implementation.     

磨料水射流偏摆切割模型及试验

为研究水射流切割特性,提高切割效率,使用量纲分析法建立偏摆切割的切深模型,并针对偏摆切割的切割特性进行试验研究.基于模型计算结果和试验数据分析了主要工艺参数特别是偏摆角度对切深和断面质量的影响.结果表明,模型能够较好地预测切深,偏摆切割可以起到加大切深和减少断面斜条纹的作用,可使切深增大的有效偏摆角范围随压力升高而扩大,最佳偏摆角度随进给速度增大而增大,随靶距提高而减小.