流式在线直播视频的采集

针对由于流媒体协议的扩展性而带来的无法实时获取流媒体数据的问题,本文在深入分析流媒体传输原理的基础上,采用基于多核的包捕获技术,解决了流式在线直播视频数据的采集问题,为局域网内流式在线直播视频的实时接收和本地保存奠定了坚实的基础。     

界面反应及界面张力对Sn-Zn-Bi焊料润湿性的影响

通过合金化的方式得到了Sn-Zn-Bi三元及Sn-Zn-Bi-Nd四元无铅焊料,采用润湿平衡法测量了其润湿力和润湿时间,并对润湿后的焊料/Cu界面组织进行了分析.结果表明:Bi元素不参与焊料/Cu界面的扩散反应,但能够通过吸附作用降低界面张力,从而提高焊料在Cu基底上的润湿力;Zn元素优先向焊料/Cu界面进行扩散形成Cu5Zn8金属间化合物,且扩散层随焊料中Zn含量的提高而增长,此时固-液界面张力方向发生改变,润湿力提高,但润湿时间延长;Nd元素的作用类似于Bi,既能提高焊料的润湿力,也能够缩短润湿时间,是一种改善Sn-Zn基焊料润湿性的有效元素.     

不完全信号时内部交易

在假设内部交易者均收到不完全信号的基础上,对该信号在交易市场中所产生的影响进行了研究;在内部交易者进行多次交易时,模型以Schimidt正交化为研究方法、以标准Cournot双寡头模型为指导思想;进而得到风险资产市场上的均衡解及相关结论.     

Lysosomal chymotrypsin B potentiates apoptosis via cleavage of Bid

We have reported that chymotrypsin B (CtrB) is not just a digestive enzyme but is also stored in lysosomes. Herein, we demonstrated a broad distribution of CtrB and explored the involvement of CtrB in apoptosis. Exposure of RH-35 cells to H₂O₂ or palmitate induced the redistribution of lysosomal CtrB into the cytoplasm as a result of lysosomal membrane permeabilization (LMP). Suppression of CtrB significantly blocked apoptosis, while overexpression of CtrB sensitized apoptosis markedly. CtrB could cleave Bid under neutral conditions. In RH-35 cells with Bid silenced, apoptosis induced by CtrB protein was attenuated, suggesting that CtrB mediates apoptosis of RH-35 cells mainly through processing Bid. Our data also suggest that LMP occurs earlier than mitochondrial outer membrane permeabilization; Bid activation initiated by caspase-8 might be reinforced by CtrB in consequence of LMP, which causes a positive feedback loop leading to the accumulation of tBid, and results in lysosome- and mitochondrion-dependent apoptosis.     

体域网中基于特征组合的步态行为识别

物联网(internet of things,IOT)拥有无处不在的识别、传感和通信能力,体域网(body area network,BAN)属于物联网中和人体相关的领域,其应用广泛,可以在日常生活中对人们进行监测及提供帮助.行走是许多日常活动的基本环节,因而步态分析能为体域网应用提供重要的生理行为信息.现有的步态分析已取得一定的研究成果,但仍存在一些问题,例如大多数步态特征提取是对加速度信号进行6重以上的变换,使得特征达到了45维以上,最后需要通过降维或优化来简化特征,较为复杂.本文设计一种灵活便捷的数据采集系统,并利用小波变换、傅里叶变换和四分位差提取出加速度信号中比较简单、低维度但能反应运动特征的步态参数,之后通过模式识别算法进行步态行为识别验证.实验结果表明该系统使用方便,特征提取方法简单实用,识别精确度为97%,EER(equal error rate)最小可到0.9%.     

月地高速再入返回器热控设计及实现

针对月地高速再入返回器不同阶段大功率散热、小功率保温与高速返回过程中高温隔热之间的突出矛盾,以及狭小、局促空间内设备热量的收集、传输、排散与阻断等技术难题,首次构建一种基于柔性自适应"热开关"的小型再入返回类航天器热控体系,成功研制出一套基于异构式环路热管的一体化柔性、高效热管理系统.在轨飞行数据表明:核心热控产品环路热管控温运行模式下实际传热能力超过65 W,阻断模式下漏热量小于2 W,"热导比"大于30,能够很好地实现"热开关"功能,确保了返回器所有设备的温度水平优于指标要求.     

Protein intrinsic disorder as a flexible armor and a weapon of HIV-1

Many proteins and protein regions are disordered in their native, biologically active states. These proteins/regions are abundant in different organisms and carry out important biological functions that complement the functional repertoire of ordered proteins. Viruses, with their highly compact genomes, small proteomes, and high adaptability for fast change in their biological and physical environment utilize many of the advantages of intrinsic disorder. In fact, viral proteins are generally rich in intrinsic disorder, and intrinsically disordered regions are commonly used by viruses to invade the host organisms, to hijack various host systems, and to help viruses in accommodation to their hostile habitats and to manage their economic usage of genetic material. In this review, we focus on the structural peculiarities of HIV-1 proteins, on the abundance of intrinsic disorder in viral proteins, and on the role of intrinsic disorder in their functions.     

Genome-wide copy number variation study associates metabotropic glutamate receptor gene networks with attention deficit hyperactivity disorder

Attention deficit hyperactivity disorder (ADHD) is a common, heritable neuropsychiatric disorder of unknown etiology. We performed a whole-genome copy number variation (CNV) study on 1,013 cases with ADHD and 4,105 healthy children of European ancestry using 550,000 SNPs. We evaluated statistically significant findings in multiple independent cohorts, with a total of 2,493 cases with ADHD and 9,222 controls of European ancestry, using matched platforms. CNVs affecting metabotropic glutamate receptor genes were enriched across all cohorts (P = 2.1 × 10(-9)). We saw GRM5 (encoding glutamate receptor, metabotropic 5) deletions in ten cases and one control (P = 1.36 × 10(-6)). We saw GRM7 deletions in six cases, and we saw GRM8 deletions in eight cases and no controls. GRM1 was duplicated in eight cases. We experimentally validated the observed variants using quantitative RT-PCR. A gene network analysis showed that genes interacting with the genes in the GRM family are enriched for CNVs in ～10% of the cases (P = 4.38 × 10(-10)) after correction for occurrence in the controls. We identified rare recurrent CNVs affecting glutamatergic neurotransmission genes that were overrepresented in multiple ADHD cohorts.     

模板法制备CexZr1-xO2及催化餐饮废油合成生物柴油

以松木为模板,使用模板法制备了不同铈锆含量的Ce_xZr_1-xO₂复合氧化物的催化剂,用于餐饮废油与甲醇进行酯交换反应合成生物柴油.采用BET、SEM对Ce_xZr_1-xO₂进行表征分析.研究不同制备方法、CeO₂的负载量和煅烧温度对催化剂活性的影响,以及不同的酯交换反应条件对生物柴油产率的影响.制备的Ce_xZr_1-xO₂具有松木的生物形态,并有助于催化剂形成多孔道结构.以Ce_xZr_1-xO₂为催化剂,考察甲醇和餐饮废油的酯交换反应.结果表明：当x=0.5,煅烧温度为600℃时,甲醇与餐饮废油物质的量比为60：1,催化剂用量（基于餐饮废油的质量）的质量分数为5%,反应温度为190℃,反应时间为6 h的反应条件下,酯交换反应的甲酯收率达到91.1%.